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Researchers reveal inherited genetic mutations associated with ovarian cancer risk

Previous research has established a link between genetic mutations in the BRCA1 and BRCA2 genes to an increased risk of developing ovarian, fallopian tube or peritoneal cancer in women.

11 Feb 2016

Boosting intrinsic growth programs can enhance axon regeneration of injured neurons

Damage to axons in the central nervous system (CNS) typically results in permanent functional deficits. Boosting intrinsic growth programs can dramatically augment the axon regeneration of injured neurons. If injured neurons can regenerate sufficient number of axons, the CNS may recover and overcome such functional deficits.

11 Feb 2016

UPMC uses simple gene test to personalize medications for patients undergoing heart catheterization

Patients who go to UPMC Presbyterian for heart catheterization and who receive a stent to treat clogged arteries are now being screened with a simple blood test to determine if they have a gene variant that makes them less likely to respond to a blood-thinning medication commonly prescribed after the procedure.

11 Feb 2016

Scientists propose use of mathematical models to find better treatment for bladder cancer

MIPT scientists together with their colleagues from St. Petersburg and Israel have analyzed more than 500 previously published scientific articles and proposed their own approach to the choice of methods used for the treatment of one of the most common cancers.

11 Feb 2016

Researchers identify genetic mutations that lower complications associated with diabetes

The most significant complications of diabetes include diabetic retinal disease, or retinopathy, and diabetic kidney disease, or nephropathy. Both involve damaged capillaries.

11 Feb 2016

Researchers use hydrogel to prevent stem cells and human embryos from differentiating

Unlike normal cells, stem cells are pluripotent -- they can become any cell type, which makes them powerful potential treatments for diseases such as diabetes, leukemia and age-related blindness. However, maintaining this versatility until the time is right is a major challenge.

11 Feb 2016

SBP researchers identify molecular switch that controls genes needed to repair skeletal muscle

Researchers at Sanford Burnham Prebys Medical Research Institute (SBP) have conclusively identified the protein complex that controls the genes needed to repair skeletal muscle.

11 Feb 2016

Kumamoto University researchers identify protein that limits severity of Alport syndrome

Researchers from Kumamoto University, Japan have identified a protein that limits the severity of Alport syndrome, a type of genetic kidney disease. The finding can provide clues that point toward new therapeutic approaches for Alport syndrome.

11 Feb 2016

New technique could help detect harmful PAMP molecules in certain processed foods

Our favourite foods could be made healthier thanks to a new technique developed by the University of Leicester which has identified harmful bacterial molecules in certain processed foods such as burgers and ready meals.

11 Feb 2016

Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

New research uncovers a cascade of reactions within nerve cells that relay sensations of pain associated with inflammation. The findings, which are published in the British Journal of Pharmacology, indicate that drugs designed to curb this pathway may help relieve inflammatory pain in sufferers.

11 Feb 2016

Neutrophils promote cardiac repair

Following an acute heart attack, immune cells called neutrophils coordinate an inflammatory response which can exacerbate the damage to the organ. Now researchers from Ludwig-Maximilians-Universitaet in Munich have shown that neutrophils also promote cardiac repair.

11 Feb 2016

Fasudil improves memory in rats, promotes degradation of toxic tau in the eyes of fruit flies

Could a kinase inhibitor some doctors prescribe to keep blood flowing after brain surgery be used to treat neurodegeneration? New research suggests it might be worth exploring the question.

10 Feb 2016

LMU researchers identify new drug target for atherosclerosis

The enzyme Dicer processes RNA transcripts, cutting them into short segments that regulate the synthesis of specific proteins. An Ludwig-Maximilians-Universitaet in Munich team has shown that Dicer promotes the development of atherosclerosis, thus identifying a new drug target.

10 Feb 2016

Helpful protein can change genetic sequence of normal cells and make mutations that cause cancers

Washington State University researchers have determined how a protein that helps cells fight viruses can also cause genetic mutations that lead to cancer.

10 Feb 2016

TxCell to update on recent achievements in cellular therapy market at leading forthcoming investor conferences

TxCell SA, a biotechnology company developing innovative, personalized cellular immunotherapies using regulatory T-cells to treat severe chronic inflammatory and autoimmune diseases, announces today that Stephane Boissel, CEO, TxCell and other senior management will either attend, present to, and meet investors at a number of leading forthcoming investor conferences.

10 Feb 2016

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

A first-ever interlaboratory study of four versions of a therapeutic protein drug—all manufactured from living cells—reports that an established analytical tool akin to magnetic resonance imaging reliably assessed the atomic structures of the biologically similar products, yielding the equivalent of a fingerprint for each.

10 Feb 2016

Muscle protein titin plays vital role in Frank-Starling mechanism

Researchers at Illinois Institute of Technology and Loyola University have discovered new clues in the 100-year-old mystery of the Frank-Starling law of the heart: What makes the heart contract more strongly at longer lengths given the same level of calcium activation?

10 Feb 2016

Diet containing unsaturated fats positively impacts weight loss and heart health markers

A new study published in the Journal of the American Heart Association found that a diet containing unsaturated fats, such as those found in walnuts and olive oil, has similar weight loss effects as a lower fat, higher-carbohydrate diet.

10 Feb 2016

Researchers sequence genetic blueprint of Lyme-disease-spreading tick

Researchers have sequenced the genetic blueprint of one of the most prolific pathogen-transmitting agents on the planet - the Lyme-disease-spreading tick (Ixodes scapularis) that bites humans. The findings could lead to advances in not only disrupting the tick's capacity to spread diseases but also in eradicating the pest.

10 Feb 2016

Barley can help reduce blood sugar levels and diabetes risk

A recent study from Lund University in Sweden shows that barley can rapidly improve people's health by reducing blood sugar levels and risk for diabetes. The secret lies in the special mixture of dietary fibres found in barley, which can also help reduce people's appetite and risk for cardiovascular disease.

10 Feb 2016

Medical Science News

Researchers reveal inherited genetic mutations associated with ovarian cancer risk

Boosting intrinsic growth programs can enhance axon regeneration of injured neurons

UPMC uses simple gene test to personalize medications for patients undergoing heart catheterization

Scientists propose use of mathematical models to find better treatment for bladder cancer

Researchers identify genetic mutations that lower complications associated with diabetes

Researchers use hydrogel to prevent stem cells and human embryos from differentiating

SBP researchers identify molecular switch that controls genes needed to repair skeletal muscle

Kumamoto University researchers identify protein that limits severity of Alport syndrome

New technique could help detect harmful PAMP molecules in certain processed foods

Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

Neutrophils promote cardiac repair

Fasudil improves memory in rats, promotes degradation of toxic tau in the eyes of fruit flies

LMU researchers identify new drug target for atherosclerosis

Helpful protein can change genetic sequence of normal cells and make mutations that cause cancers

TxCell to update on recent achievements in cellular therapy market at leading forthcoming investor conferences

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

Muscle protein titin plays vital role in Frank-Starling mechanism

Diet containing unsaturated fats positively impacts weight loss and heart health markers

Researchers sequence genetic blueprint of Lyme-disease-spreading tick

Barley can help reduce blood sugar levels and diabetes risk

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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