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New technique improves accuracy of CRISPR/Cas9 gene editing system

A new CRISPR/Cas9 technology developed by scientists at the University of Massachusetts Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.

19 Nov 2015

Role of biomarkers in drug development and regulatory decision making

Biomarkers in Medicine, a leading MEDLINE-indexed journal, has published a special focus issue exploring the increasingly important role of biomarkers in both drug development and regulatory decision making.

19 Nov 2015

Scientists, chefs explore ways to help people with neurologically-related taste impairments enjoy food again

Two women, seated at a table, told their stories in quiet tones. A group of chefs, some standing, others seated, leaned forward eagerly, clearly interested in what these two women had to say. They peppered the women with questions: did food taste better cold or hot? Was texture an issue? Did a glass of wine before dinner help or hurt the flavor experience? The women have taken chemotherapy for their cancer. One of them -- Gina Mullin -- will be taking chemotherapy every three weeks for the rest of her life. Both of them tell heartbreaking stories about a side effect of chemotherapy that gets swept under the rug: food tastes terrible.

19 Nov 2015

Sound deprivation causes irreversible damage to the inner ear

Massachusetts Eye and Ear investigators have shown that sound deprivation in adult mice causes irreversible damage to the inner ear. The findings, published in PLOS ONE, suggest that chronic conductive hearing loss, such as that caused by recurrent ear infections, leads to permanent hearing impairment if it remains untreated.

19 Nov 2015

Dartmouth study reveals the brain's visual pathways

A Dartmouth study reveals how the brain understands motion and still objects to help us navigate our complex visual world.

19 Nov 2015

IMB scientists unravel complex regulatory mechanism involved in brain development

Scientists at the Institute of Molecular Biology in Mainz have unraveled a complex regulatory mechanism that explains how a single gene can drive the formation of brain cells. The research, published in The EMBO Journal, is an important step towards a better understanding of how the brain develops. It also harbors potential for regenerative medicine.

19 Nov 2015

Houston Methodist invention named one of 100 most innovative technologies by R&D Magazine

R&D Magazine named the handheld single-cell pipette (hSCP), a Houston Methodist Research Institute invention, as one the 100 most innovative technologies and services of the past year.

19 Nov 2015

International task force aims to develop new approach to cancer prevention and treatment

Advancements in precision medicine have led to many new targeted cancer therapies for cancer patients. These treatments focus on using agents that target one or two genes that contribute to tumor development. The approach tends to be more effective against cancer cells and less toxic toward normal cells than standard chemotherapeutic regimens.

19 Nov 2015

ICGC announces availability of more genomic data on Amazon Web Services Cloud for cancer researchers

The International Cancer Genome Consortium announced today that 1,200 encrypted cancer whole genome sequences are now securely available on the Amazon Web Services (AWS) Cloud for access by cancer researchers worldwide.

19 Nov 2015

Potential treatment strategy for glycogen storage disease

Researchers from the Duke-NUS Graduate Medical School Singapore and Duke Medicine have identified a potential treatment strategy for an often-fatal inherited glycogen storage disease.

18 Nov 2015

Cell Therapy Catapult initiates construction for cell and gene therapy manufacturing centre

The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the official initiation of construction for its cell and gene therapy manufacturing centre.

18 Nov 2015

Duchenne muscular dystrophy could directly affect muscle stem cells

A new study from The Ottawa Hospital and the University of Ottawa is poised to completely change our understanding of Duchenne muscular dystrophy and pave the way for far more effective treatments.

18 Nov 2015

Serum phosphorus levels can help predict risk of ESRD in African Americans with CKD

An increase in serum phosphorus levels in African Americans with chronic kidney disease (CKD) is associated with faster progression to kidney failure, known as end-stage renal disease (ESRD), according to new research presented at ASN Kidney Week 2015 November 3-8 in San Diego, CA. Previously confirmed in primarily Caucasian populations, the Indiana University School of Medicine study confirms serum phosphorus is linked to ESRD risk in African Americans.

18 Nov 2015

Scientists identify mechanism that may help prostate cancer cells escape effects of cancer drugs

Advanced prostate cancer is a disease notoriously resistant to treatment. New research by scientists at Fred Hutchinson Cancer Research Center and the University of California, San Francisco sheds light on a new mode of drug resistance to emerging therapies in metastatic prostate cancer.

18 Nov 2015

IU researchers discover hormonal mechanism that links short winter days with increased aggression in females

Indiana University researchers have discovered a hormonal mechanism in hamsters that connects short winter days with increased aggression in females, and that it differs from the mechanism that controls this same response in males.

18 Nov 2015

Facebook can have both positive and negative effects on teens' stress hormone levels

Facebook can have positive and negative effects on teens levels of a stress hormone, say researchers at the University of Montreal and the Institut universitaire de santé mentale de Montréal. Led by Professor Sonia Lupien, the team found that having more than 300 Facebook friends increased teens' levels of cortisol.

18 Nov 2015

Scientists succeed in promoting regeneration of injured neurons in zebrafish by the use of light

The nervous system is built to last a lifetime, but diverse diseases or environmental insults can overpower the capacity of neurons to maintain function or to repair after trauma. A team led by Dr. Hernán López-Schier, head of the Research Unit Sensory Biology and Organogenesis at Helmholtz Zentrum München, now succeeded in promoting the repair of an injured neural circuit in zebrafish.

18 Nov 2015

NRL researchers to develop next generation of functional materials to map brain connections

Research biologists, chemists and theoreticians at the U.S. Naval Research Laboratory, are on pace to develop the next generation of functional materials that could enable the mapping of the complex neural connections in the brain. The ultimate goal is to better understand how the billions of neurons in the brain communicate with one another during normal brain function, or dysfunction, as result of injury or disease.

18 Nov 2015

Elite endurance athletes who eat few carbohydrates burn more fat during prolonged exercise

Elite endurance athletes who eat very few carbohydrates burned more than twice as much fat as high-carb athletes during maximum exertion and prolonged exercise in a new study - the highest fat-burning rates under these conditions ever seen by researchers.

18 Nov 2015

Scientists explain the evolutionary roots of language in the brain

A team led at Newcastle University, UK, has shed light on the evolutionary roots of language in the brain. Publishing in Nature Communications, the team led by Dr Ben Wilson and Professor Chris Petkov explain how using an imaging technique to explore the brain activity in humans and monkeys has identified the evolutionary origins of cognitive functions in the brain that underpin language and allow us to evaluate orderliness in sequences of sounds.

18 Nov 2015

Medical Science News

New technique improves accuracy of CRISPR/Cas9 gene editing system

Role of biomarkers in drug development and regulatory decision making

Scientists, chefs explore ways to help people with neurologically-related taste impairments enjoy food again

Sound deprivation causes irreversible damage to the inner ear

Dartmouth study reveals the brain's visual pathways

IMB scientists unravel complex regulatory mechanism involved in brain development

Houston Methodist invention named one of 100 most innovative technologies by R&D Magazine

International task force aims to develop new approach to cancer prevention and treatment

ICGC announces availability of more genomic data on Amazon Web Services Cloud for cancer researchers

Potential treatment strategy for glycogen storage disease

Cell Therapy Catapult initiates construction for cell and gene therapy manufacturing centre

Duchenne muscular dystrophy could directly affect muscle stem cells

Serum phosphorus levels can help predict risk of ESRD in African Americans with CKD

Scientists identify mechanism that may help prostate cancer cells escape effects of cancer drugs

IU researchers discover hormonal mechanism that links short winter days with increased aggression in females

Facebook can have both positive and negative effects on teens' stress hormone levels

Scientists succeed in promoting regeneration of injured neurons in zebrafish by the use of light

NRL researchers to develop next generation of functional materials to map brain connections

Elite endurance athletes who eat few carbohydrates burn more fat during prolonged exercise

Scientists explain the evolutionary roots of language in the brain

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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