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New study pinpoints complex genetic origins for autoimmune diseases

Scores of autoimmune diseases afflicting one in 12 Americans — ranging from type 1 diabetes, to multiple sclerosis (MS), to rheumatoid arthritis, to asthma — mysteriously cause the immune system to harm tissues within our own bodies. Now, a new study pinpoints the complex genetic origins for many of these diseases, a discovery that may lead to better diagnosis and ultimately to improved treatments.

30 Oct 2014

UCLA scientists find link between gigaxonin protein and HPV-positive head and neck cancers

UCLA scientists have discovered for the first time that a protein usually linked to rare neurological disorders is also associated with human papilloma virus (HPV) positive head and neck cancers. The protein was also shown to help improve the effectiveness of chemotherapy treatments, laying the groundwork for the development of more specialized therapies.

30 Oct 2014

Landmark study provides new insight into function of enzyme related to BRCA1 protein

A landmark study to be published in the October 30, 2014 print edition of the journal Nature provides new insight into the function of an enzyme related to the BRCA1 breast-cancer protein. The study by a team at Penn State University is the first to produce a detailed working image of an enzyme in the Polycomb Repressive Complex 1 (PRC1) -- a group that regulates cell development and is associated with many types of cancer.

30 Oct 2014

UCLA research could lead to simple saliva test for early diagnosis of deadly diseases

UCLA research could lead to a simple saliva test capable of diagnosing — at an early stage — diabetes and cancer, and perhaps neurological disorders and autoimmune diseases.

30 Oct 2014

Biology influences political ideology, find Virginia Tech scientists

Maggot infestations, rotting carcasses, unidentifiable gunk in the kitchen sink – how much your brain responds to disgusting images could predict whether you are liberal or conservative.

30 Oct 2014

New study reveals link between aristolochic acid and kidney cancer

A new study on a large cohort of kidney cancer patients in Europe sheds light on the genetic architecture of the disease -- and reveals an apparent link between exposure to aristolochic acid and incidence of kidney cancer, particularly in Romania.

29 Oct 2014

Genetic differences contribute to risk for autism

Small differences in as many as a thousand genes contribute to risk for autism, according to a study led by Mount Sinai researchers and the Autism Sequencing Consortium, and published today in the journal Nature.

29 Oct 2014

Researchers use DNA sequencing to uncover genes that heighten autism risk

In the largest study of its kind to date, researchers have used DNA sequencing to uncover dozens of genes that heighten the risk for autism. Joseph Buxbaum, Ph.D., Icahn School of Medicine at Mount Sinai, New York City, Mark Daly, Ph.D., Broad Institute of Harvard and MIT, and their colleagues examined more than 14,000 DNA samples from affected children, parents and unrelated people.

29 Oct 2014

Researchers find potential target for therapies to treat cocaine addiction

A study led by investigators from Massachusetts General Hospital and the Perelman School of Medicine at the University of Pennsylvania has identified a potential target for therapies to treat cocaine addiction.

29 Oct 2014

Study: New blood substitute may be safer than donor blood

A new blood substitute has been developed which could be a safer and more effective alternative to using donor blood.

29 Oct 2014

New international consortium to advance GPCR research for drug development

The generation of high-resolution pictures of hundreds of medically important proteins known as G-protein coupled receptors (GPCRs) will be the goal of an ambitious new international partnership. Called the GPCR Consortium, this non-profit initiative brings together major pharmaceutical companies and leading research institutes from three continents to advance GPCR research for drug development.

29 Oct 2014

Patient's gene profile influences effects of statins

The Montreal Heart Institute Research Centre is once again pushing the limits of knowledge in personalized medicine. A meta-analysis combining the results of several pharmacogenomic studies and involving over 40,000 research subjects now makes it possible to demonstrate a different response to statins according to the patient's gene profile.

29 Oct 2014

Study sheds light on the mystery of biological clock that controls fertility in women

Researchers at the University of Gothenburg have identified the biological clock that governs female fertility. The discovery represents a major contribution to research aimed at finding medical approaches to treating infertility in women.

29 Oct 2014

Rapamycin and dasatinib combination may be beneficial in treating breast cancer, say scientists

The uncontrolled growth of cancer cells arises from their ability to hijack the cell’s normal growth program and checkpoints. Usually after therapy, a second cancer-signaling pathway will open after the primary one shuts down — creating an ingenious escape route for the cancer cell to survive. The answer, say Case Western Reserve researchers, is to anticipate and block that back-up track by prescribing two drugs from the start.

29 Oct 2014

TSRI scientists discover signaling pathway that contribute to Huntington's disease

Scientists from the Florida campus of The Scripps Research Institute have uncovered a major contributor to Huntington's disease, a devastating progressive neurological condition that produces involuntary movements, emotional disturbance and cognitive impairment.

29 Oct 2014

Teen binge drinking effects may last a lifetime, suggests UMass Amherst study

Binge drinking can have lasting effects on brain pathways that are still developing during adolescence, say neuroscience researcher Heather N. Richardson and her colleagues at the University of Massachusetts Amherst and Louisiana State University.

29 Oct 2014

Same cell type can give rise to different gliomas

Glioma is a common name for serious brain tumours. Different types of glioma are usually diagnosed as separate diseases and have been considered to arise from different cell types in the brain.

29 Oct 2014

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

The classic description of game theory was described by the prisoner's dilemma, which is a situation in which two players have two options where the outcome depends on the simultaneous choice made by the other.

29 Oct 2014

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approximately four million disability-adjusted life years lost due to chronic illness and death each year.

28 Oct 2014

Olympus cellSens imaging software 1.12 offers new functions

Assisting researchers in gaining a deeper understanding of dynamic biological processes, the new cellSens imaging software (version 1.12) ensures the most efficient use of valuable time-lapse experiments and the latest microscopy hardware. Building on the capabilities introduced by Olympus with its unique Graphical Experiment Manager (GEM) interface, cellSens 1.12 allows the user to truly get in touch with their sample.

From Evident Corporation - Life Sciences 28 Oct 2014

Medical Science News

New study pinpoints complex genetic origins for autoimmune diseases

UCLA scientists find link between gigaxonin protein and HPV-positive head and neck cancers

Landmark study provides new insight into function of enzyme related to BRCA1 protein

UCLA research could lead to simple saliva test for early diagnosis of deadly diseases

Biology influences political ideology, find Virginia Tech scientists

New study reveals link between aristolochic acid and kidney cancer

Genetic differences contribute to risk for autism

Researchers use DNA sequencing to uncover genes that heighten autism risk

Researchers find potential target for therapies to treat cocaine addiction

Study: New blood substitute may be safer than donor blood

New international consortium to advance GPCR research for drug development

Patient's gene profile influences effects of statins

Study sheds light on the mystery of biological clock that controls fertility in women

Rapamycin and dasatinib combination may be beneficial in treating breast cancer, say scientists

TSRI scientists discover signaling pathway that contribute to Huntington's disease

Teen binge drinking effects may last a lifetime, suggests UMass Amherst study

Same cell type can give rise to different gliomas

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Olympus cellSens imaging software 1.12 offers new functions

Making Complex Cell Culture Easy and Efficient with AI

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

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