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Six research institutions awarded NIH grants to create database of human cellular responses

Building on a successful three-year pilot project, the National Institutes of Health has awarded more than $64 million to six research institutions to create a database of human cellular responses, the Library of Integrated Network-based Cellular Signatures.

15 Sep 2014

Scientists measure responses to rewards during nicotine withdrawal across species

Cigarette smoking is a leading cause of preventable death worldwide and is associated with approximately 440,000 deaths in the United States each year, according to the U.S. Centers for Disease Control and Prevention, but nearly 20 percent of the U.S. population continues to smoke cigarettes.

15 Sep 2014

Global study shows accuracy of RNA genomic sequencing techniques

Physicians envision a future in which genomic data from patients is heavily used to manage care - but experts have questioned the accuracy and reliability of these analyses. Now, a study by 150 researchers in 12 countries finds real strength and agreement across RNA genomic sequencing techniques and laboratories - as well as ways to improve what little variability exists to set a new high standard.

15 Sep 2014

New study measures neurodevelopment in schizophrenia

Schizophrenia is generally considered to be a disorder of brain development and it shares many risk factors, both genetic and environmental, with other neurodevelopmental disorders such as autism and intellectual disability.

15 Sep 2014

BGI-VPC Joint Research Laboratory to apply genome research to develop new cancer therapies

BGI, the world’s largest genomics organization, based in China, and The Vancouver Prostate Centre, a global leader in translational research in cancer, today announced the establishment of the BGI-VPC Joint Research Laboratory, a sequencing and translational research facility, to jointly discover and advance basic and translational programs in oncology, including personalized oncology.

15 Sep 2014

New antiseptic agent holds promise for treatment of periodontitis

The study, published in the journal Science and Technology of Advanced Materials, by Shinichi Arakawa and colleagues at Tokyo Medical and Dental University and Japan's National Institute of Advanced Industrial Science and Technology, evaluated the bactericidal activities of ozone nano-bubble water - also known as NBW3 - against the two main bacterial agents that cause periodontitis as well as its toxicity to human oral tissue cells.

15 Sep 2014

Gut hormone-drug combination therapy more effective at improving type 2 diabetes

Combined treatment with a drug that mimics the action of a gut hormone and basal insulin is more effective at improving blood sugar control than other anti-diabetic treatments, with similar rates of hypoglycaemia (dangerously low blood sugar levels) and greater weight loss, a systematic review and meta-analysis published in The Lancet shows.

15 Sep 2014

GILZ protein key to preventing bone loss, researchers report

A small protein named GILZ appears to protect against the bone loss that often accompanies arthritis and its treatment, researchers report.

15 Sep 2014

Brain structure 'significantly predictive' of individual risk attitudes

There is a link between our brain structure and our tolerance of risk, new research suggests.

15 Sep 2014

Researchers find learning and memory components of neurofibromatosis using zebrafish model

Using a zebrafish model of a human genetic disease called neurofibromatosis (NF1), a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches.

15 Sep 2014

Researchers report that dendritic cells can affect psoriasis

Different types of dendritic cells in human skin have assorted functions in the early and more advanced stages of psoriasis report researchers in the journal EMBO Molecular Medicine.

15 Sep 2014

UC Irvine study sheds light on cognitive losses

Brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences, according to UC Irvine neuroscientists Jennifer Czerniawski and John Guzowski.

15 Sep 2014

Postmenopausal women with diverse gut bacteria exhibit more favorable ratio of estrogen metabolites

Postmenopausal women with diverse gut bacteria exhibit a more favorable ratio of estrogen metabolites, which is associated with reduced risk for breast cancer, compared to women with less microbial variation, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

12 Sep 2014

New class of compounds protect brain cells from traumatic brain injury

A new class of compounds has now been shown to protect brain cells from the type of damage caused by blast-mediated traumatic brain injury (TBI).

12 Sep 2014

Human stem cells can be reset to their native undifferentiated state

Scientists at the Babraham Institute, in collaboration with colleagues at the Cambridge Stem Cell Institute and the European Bioinformatics Institute, have made a breakthrough in stem cell research. Their paper, published today in Cell, describes how human stem cells can be reverted back to non-specialised cells.

11 Sep 2014

Researchers discover new details of how autoantibodies destroy healthy cells in skin

University at Buffalo researchers and colleagues studying a rare, blistering disease have discovered new details of how autoantibodies destroy healthy cells in skin.

11 Sep 2014

Olympus launches objective lenses, enabling super-deep imaging of tissues, live-cell imaging and light sheet microscopy techniques

Dedicated to multiphoton excitation microscopy, Olympus introduces its XLPLN10XSVMP and XLSLPLN25XGMP objective lenses with an 8 mm working distance and support for a large range of refractive indices (RI). The objectives enable super-deep imaging of tissues treated with the latest clearing agents as well as live-cell imaging and light sheet microscopy techniques.

From Evident Corporation - Life Sciences 11 Sep 2014

Medical Science News

Six research institutions awarded NIH grants to create database of human cellular responses

Scientists measure responses to rewards during nicotine withdrawal across species

Global study shows accuracy of RNA genomic sequencing techniques

New study measures neurodevelopment in schizophrenia

BGI-VPC Joint Research Laboratory to apply genome research to develop new cancer therapies

New antiseptic agent holds promise for treatment of periodontitis

Gut hormone-drug combination therapy more effective at improving type 2 diabetes

GILZ protein key to preventing bone loss, researchers report

Brain structure 'significantly predictive' of individual risk attitudes

Researchers find learning and memory components of neurofibromatosis using zebrafish model

Researchers report that dendritic cells can affect psoriasis

UC Irvine study sheds light on cognitive losses

Postmenopausal women with diverse gut bacteria exhibit more favorable ratio of estrogen metabolites

New class of compounds protect brain cells from traumatic brain injury

Human stem cells can be reset to their native undifferentiated state

Researchers discover new details of how autoantibodies destroy healthy cells in skin

Olympus launches objective lenses, enabling super-deep imaging of tissues, live-cell imaging and light sheet microscopy techniques

Researchers hope to find new ways to combat age-related diseases

Research gives scientists new insight into evolution of gibbon genome

More research needed to prevent brains of sportspeople from injury

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

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