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Scientists discover new pathway to manipulate, maintain human ESCs in a "na-ve"

For years, researchers and patients have hoped that embryonic stem cells (ESCs)-capable of forming nearly any cell type in the body-could provide insight into numerous diseases perhaps even be used to treat them. Yet progress has been hampered by the inability to transfer research and tools from mouse ESC studies to their human counterparts, in part because human ESCs are "primed" and slightly less plastic than the mouse cells.

26 Jul 2014

Genetics involved with menarche may hold keys to preventing diabetes or osteoporosis in later life

A novel study shows that the age girls reach puberty is influenced by 'imprinted genes'-a subset of genes whose activity differs depending on which parent contributes the gene.

26 Jul 2014

XPro1595 drug can protect vulnerable neurons, reduce motor deficits in Parkinson's model

An experimental anti-inflammatory drug can protect vulnerable neurons and reduce motor deficits in a rat model of Parkinson's disease, researchers at Emory University School of Medicine have shown.

26 Jul 2014

New textbook on tissue engineering and artificial organ development

Ravi Birla, associate professor of biomedical engineering at the University of Houston, has written a new textbook on tissue engineering and artificial organ development.

26 Jul 2014

New way for development of barley with resistance to powdery mildew

New research at the University of Adelaide has opened the way for the development of new lines of barley with resistance to powdery mildew.

26 Jul 2014

Epigenetic switch can cause cancer, shows study

Cancer has long been thought to be primarily a genetic disease, but in recent decades scientists have come to believe that epigenetic changes - which don't change the DNA sequence but how it is 'read' - also play a role in cancer.

26 Jul 2014

Autophagy prevents accumulation of toxic proteins associated with type 2 diabetes

People with Type 2 diabetes have an excess of a protein called islet amyloid polypeptide, or IAPP, and the accumulation of this protein is linked to the loss of insulin-producing pancreatic beta cells.

25 Jul 2014

CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

Over half of patients being seen in the clinic for a diagnosed brain tumor have metastatic cancer, which has no treatment and detrimental outcomes in most cases.

25 Jul 2014

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found.

25 Jul 2014

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Millions of people in the United States have a circulatory problem of the legs called peripheral vascular disease. It can be painful and may even require surgery in serious cases. This disease can lead to severe skeletal muscle wasting and, in turn, limb amputation.

25 Jul 2014

Immunologic mechanism makes broadly neutralizing antibodies in people infected with HIV

Scientists at Duke Medicine have found an immunologic mechanism that makes broadly neutralizing antibodies in people who are HIV-1 infected.

25 Jul 2014

Discovery could lead to novel drugs to tackle melanoma

Skin Cancer cells work together to spread further and faster, according to a new study published in Cell Reports. The discovery could lead to new drugs to tackle melanoma, the most deadly form of skin cancer.

25 Jul 2014

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers at UC San Francisco (UCSF) have discovered that endostatin, a protein that once aroused intense interest as a possible cancer treatment, plays a key role in the stable functioning of the nervous system.

25 Jul 2014

Researchers working to develop new drugs for treating chronic inflammatory diseases

Science and industry are collaborating to develop future pharmaceuticals for treating chronic inflammatory diseases. The medicines will combat immunological processes that have gone wrong.

25 Jul 2014

Immune system play role in memory impairment associated with chronic epilepsy

Could the body's own immune system play a role in memory impairment and cognitive dysfunction associated with conditions like chronic epilepsy, Alzheimer's dementia and concussions? Cleveland Clinic researchers believe so, based on a study published online by PLOS ONE.

25 Jul 2014

New version of drug successfully treats lupus in mice

Expanding on his work with a new drug that successfully treated lupus in mice, a biomedical engineer at the University of Houston has received a $250,000 grant to expand his research to a new version of the drug in an effort to treat a wider range of autoimmune diseases.

25 Jul 2014

Medical Science News

Scientists discover new pathway to manipulate, maintain human ESCs in a "na-ve"

Genetics involved with menarche may hold keys to preventing diabetes or osteoporosis in later life

XPro1595 drug can protect vulnerable neurons, reduce motor deficits in Parkinson's model

New textbook on tissue engineering and artificial organ development

New way for development of barley with resistance to powdery mildew

Epigenetic switch can cause cancer, shows study

Autophagy prevents accumulation of toxic proteins associated with type 2 diabetes

CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Immunologic mechanism makes broadly neutralizing antibodies in people infected with HIV

Discovery could lead to novel drugs to tackle melanoma

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers working to develop new drugs for treating chronic inflammatory diseases

Immune system play role in memory impairment associated with chronic epilepsy

New version of drug successfully treats lupus in mice

Natural products from plants can protect skin against gamma radiation during radiotherapy

Effective way to fight against certain species of toxic grass fungus: moose saliva

Asia's first genetic test developed for identifying patients with corneal stromal dystrophy

Scientists one step closer to creating viable cell replacement therapy for multiple sclerosis patients

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

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