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Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

The natural DNA bases that form the letters of DNA are usually referred to as G, C, A, and T. Those are only the first letters of the chemical names. They’re often called nucleotides by their scientific name and all of them have in common a phosphate part, a sugar part and a nucleobase part.

21 Jul 2014

New York State DOH grants RPCI approval to begin genomic testing of cancer patients

The New York State Department of Health (DOH) has granted Roswell Park Cancer Institute (RPCI) approval to begin genomic testing of cancer patients using its OmniSeq TargetTM advanced molecular diagnostic laboratory test.

21 Jul 2014

Study: L-carnitine has neuroprotective effects on injured sciatic nerve of rats

Several studies have demonstrated that L-carnitine exhibits neuroprotective effects on injured sciatic nerve of rats with diabetes mellitus.

21 Jul 2014

A personalized approach for patients with ccRCC-related mutations

In an analysis of small molecules called metabolites used by the body to make fuel in normal and cancerous cells in human kidney tissue, a research team from the Perelman School of Medicine at the University of Pennsylvania identified an enzyme key to applying the brakes on tumor growth.

21 Jul 2014

IL-10 enhances positive benefits of transplanted allogenic SMCs to repair cardiac tissues after MI

The long-term, positive benefits of transplanted allogenic (other-donated) smooth muscle cells (SMCs) to repair cardiac tissues after myocardial infarction (MI) have been enhanced by the addition of interleukin 10 (IL-10) to the transplanted cells, report researchers in Canada.

21 Jul 2014

Sciatic nerve injury can cause differential expression of microRNAs in dorsal root ganglia

Slit-Robo GTPase-activating protein 3 contains a Rho GAP domain that regulates the activities of Rho family GTPases and affects actin polymerization, which influences dendrite elaboration, neurite outgrowth and axon guidance, contributing to neural regeneration.

21 Jul 2014

Scientist uses samples of beating heart tissue to test effect of drugs

A Coventry University scientist has developed a pioneering new way - using samples of beating heart tissue - to test the effect of drugs on the heart without using human or animal trials.

21 Jul 2014

Study provides evidence for intranasal nerve growth factor for repair of spinal cord injury

Nerve growth factor can be delivered to the brain by intranasal administration without risk for treatment of brain diseases.

21 Jul 2014

Growth hormone reduces liver fat in HIV-infected patients with excess abdominal fat

In a preliminary study, HIV-infected patients with excess abdominal fat who received the growth hormone-releasing hormone analog tesamorelin for 6 months experienced modest reductions in liver fat, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.

21 Jul 2014

Enhancing autophagy in pre-diabetic patients has potential to prevent onset of diabetes

Diabetes affects almost 400 million people worldwide. One of the hallmarks of this disease is a loss of pancreatic β cells, which secrete insulin. In many patients the reduction of β cells is associated an accumulation of a toxic form of a protein produced by β cells, known as islet amyloid polypeptide.

21 Jul 2014

Study: Dietary elimination is successful method of treatment for adults with EoE

Dietary elimination is a successful method of treatment for adults with eosinophilic esophagitis (EoE), according to a new study1 in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

21 Jul 2014

Researchers identify group of cells in brain that plays important role in Down syndrome

Researchers from UC Davis School of Medicine and Shriners Hospitals for Children - Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome.

21 Jul 2014

New material can extract atoms of rare or dangerous elements from air

Scientists at the University of Liverpool have successfully tested a material that can extract atoms of rare or dangerous elements such as radon from the air.

21 Jul 2014

Scientists reveal structure of protein involved in life and development of cancer

Scientists reveal the structure of one of the most important and complicated proteins in cell division - a fundamental process in life and the development of cancer - in research published in Nature today (Sunday).

21 Jul 2014

Marmoset's unique rapid reproductive system sheds new light on evolution and primate biology

A team of scientists from around the world led by Baylor College of Medicine and Washington University in St. Louis has completed the genome sequence of the common marmoset - the first sequence of a New World Monkey - providing new information about the marmoset's unique rapid reproductive system, physiology and growth, shedding new light on primate biology and evolution.

21 Jul 2014

Common genetic variation in gene may modify cardiovascular benefit of aspirin

Aspirin is the gold standard for antiplatelet therapy and a daily low-dose aspirin is widely prescribed for the prevention of cardiovascular disease.

21 Jul 2014

Study: Genetics plays major role in development of autism

Using new statistical tools, Carnegie Mellon University's Kathryn Roeder has led an international team of researchers to discover that most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches.

21 Jul 2014

Discovery presents new challenges for HIV eradication efforts

The most critical barrier for curing HIV-1 infection is the presence of the viral reservoir, the cells in which the HIV virus can lie dormant for many years and avoid elimination by antiretroviral drugs. Very little has been known about when and where the viral reservoir is established during acute HIV-1 infection, or the extent to which it is susceptible to early antiretroviral therapy (ART).

21 Jul 2014

Researchers develop new single-cell technique to study environmental effects on DNA

Researchers at the BBSRC-funded Babraham Institute, in collaboration with the Wellcome Trust Sanger Institute Single Cell Genomics Centre, have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents.

21 Jul 2014

Scientists make seminal breakthrough in understanding molecular basis of fibroadenoma

A multi-disciplinary team of scientists from the National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, and Singapore General Hospital have made a seminal breakthrough in understanding the molecular basis of fibroadenoma, one of the most common breast tumours diagnosed in women.

21 Jul 2014

Medical Science News

Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

New York State DOH grants RPCI approval to begin genomic testing of cancer patients

Study: L-carnitine has neuroprotective effects on injured sciatic nerve of rats

A personalized approach for patients with ccRCC-related mutations

IL-10 enhances positive benefits of transplanted allogenic SMCs to repair cardiac tissues after MI

Sciatic nerve injury can cause differential expression of microRNAs in dorsal root ganglia

Scientist uses samples of beating heart tissue to test effect of drugs

Study provides evidence for intranasal nerve growth factor for repair of spinal cord injury

Growth hormone reduces liver fat in HIV-infected patients with excess abdominal fat

Enhancing autophagy in pre-diabetic patients has potential to prevent onset of diabetes

Study: Dietary elimination is successful method of treatment for adults with EoE

Researchers identify group of cells in brain that plays important role in Down syndrome

New material can extract atoms of rare or dangerous elements from air

Scientists reveal structure of protein involved in life and development of cancer

Marmoset's unique rapid reproductive system sheds new light on evolution and primate biology

Common genetic variation in gene may modify cardiovascular benefit of aspirin

Study: Genetics plays major role in development of autism

Discovery presents new challenges for HIV eradication efforts

Researchers develop new single-cell technique to study environmental effects on DNA

Scientists make seminal breakthrough in understanding molecular basis of fibroadenoma

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

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