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PIONEER software breaks down barriers in protein-protein interaction research

Scientists from Cleveland Clinic and Cornell University have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication.

24 Oct 2024

Low-carb diet may improve beta-cell function in type 2 diabetes patients

This study shows a carbohydrate-restricted diet boosts β-cell function in type 2 diabetes, offering a sustainable approach to manage the disease effectively.

24 Oct 2024

Arthritis-style immunotherapy shows promise for heart failure

A study uncovers IL-1β signaling in cardiac fibrosis, highlighting distinct fibroblast populations and promising immunotherapy strategies for heart failure.

24 Oct 2024

Secure computing enables collaborative cancer research

The research project Federated Secure Computing, funded by the Stifterverband, handles cancer patient data analysis in the European health data space across national borders without sharing any actual data, utilizing the modern cryptographic method - secure multiparty computation. The European research team includes scientists from LMU Munich, Germany, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Italy, and cryptography experts from Cybernetica, Estonia.

24 Oct 2024

Researchers identify mechanism of immune suppression in ovarian cancer

Weill Cornell Medicine researchers have discovered a mechanism that ovarian tumors use to cripple immune cells and impede their attack—blocking the energy supply T cells depend on. The study, published Oct. 23 in Nature, points toward a promising new immunotherapy approach for ovarian cancer, which is notoriously aggressive and hard to treat.

24 Oct 2024

How your baby’s birth and environment can shape lifelong gut health

Early life factors, like birth mode and green environments, shape infant gut microbiota, with outdoor time becoming crucial in late infancy. Residential greenery impacts diversity only during early infancy.

24 Oct 2024

Tibetan women’s high-altitude adaptations drive greater reproductive success

Researchers uncover how specific genetic and cardiovascular traits give Tibetan women an edge in surviving and thriving at high altitudes, linking better oxygen delivery to more successful pregnancies.

23 Oct 2024

Deforestation drives a surge in malaria cases in the Amazon

Deforestation in the Brazilian Amazon is linked to a rise in malaria cases, with a 1% increase in deforestation leading to a 6.3% spike in cases the following month. This relationship is strongest in highly forested and indigenous areas.

23 Oct 2024

Repeated mRNA vaccinations enhance mucosal antibody production

During the COVID pandemic, many of us have received multiple mRNA vaccines. New work by researchers at the VIB-UGent Center for Inflammation Research, Ghent University, and University Hospital Ghent, among others, has found that such repeated vaccinations lead to the presence of mucosal antibodies, for example, inside the nose. Their work appears in Science Translational Medicine.

23 Oct 2024

New antibody platform targets evolving viruses

Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.

23 Oct 2024

3D-printed model created to mimic cancer metastasis

Scientists have created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells.

23 Oct 2024

Researchers create mini-brains to study autism and test new treatments

Using stem cells generated from patients with a rare and severe form of autism spectrum disorder and intellectual disability, Scripps Research scientists have grown personalized "mini-brains" (or organoids) to study the disorder in new detail.

23 Oct 2024

Poor sleep quality linked to increased brain aging in middle age

People in early middle age who have poor sleep quality, including having difficulty falling or staying asleep, have more signs of poor brain health in late middle age, according to a study published in the October 23, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Oct 2024

Study reveals innovative treatment for narcolepsy-related nightmares

A new Northwestern Medicine study has demonstrated a new way to treat narcolepsy-related nightmares.

23 Oct 2024

Urine RNA analysis shows promise for detecting genitourinary diseases

Early detection is critical when it comes to curing diseases like cancer, but not everyone has easy access to screening tools.

23 Oct 2024

Breakthrough research reveals neural basis of eating behavior

Speaking, singing, coughing, laughing, yelling, yawning, chewing-;we use our jaws for many purposes. Each action requires a complex coordination of muscles whose activity is managed by neurons in the brain.

23 Oct 2024

Immunotherapy may be an effective treatment strategy for heart failure

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy -; similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis -; also may be an effective treatment strategy for heart failure.

23 Oct 2024

Researchers discover how ovarian tumors cripple immune cells

Weill Cornell Medicine researchers have discovered a mechanism that ovarian tumors use to cripple immune cells and impede their attack-;blocking the energy supply T cells depend on.

23 Oct 2024

Multigene RNA signature enhances treatment strategies for triple negative breast cancer

Using a gene signature technique to tailor chemotherapy for patients with early triple negative breast cancer shows promise as a way to improve disease-free survival, finds a clinical trial published by The BMJ today.

23 Oct 2024

Maternal antibodies may hinder malaria vaccine effectiveness in infants

Maternal antibodies passed across the placenta can interfere with the response to the malaria vaccine, which would explain its lower efficacy in infants under five months of age, according to research led by the Barcelona Institute for Global Health (ISGlobal), in collaboration with seven African centers (CISM-Mozambique, IHI-Tanzania, CRUN-Burkina Faso, KHRC-Ghana, NNIMR-Ghana, CERMEL-Gabon, KEMRI-Kenya).

23 Oct 2024