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Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University) and Dr. Xuguang Du (College of Biological Sciences, China Agricultural University) and illustrated the key role of Mettl3 in CD8 T cell response during acute infection model.

29 Dec 2023

Microbial decoration enhances drug delivery specificity and safety

Announcing a new publication for Acta Materia Medica journal. Microorganisms are mostly distributed on the surface of our skin and intestines and have crucial roles in physiologic and metabolic processes, such as digestion and immunity, which are closely related to diseases.

29 Dec 2023

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

A new study shows thousands more patients diagnosed with colorectal and endometrial cancers could benefit from immunotherapy than are currently offered it.

29 Dec 2023

'Visual system' protein appears to be key for stabilizing the body's circadian rhythms

Scientists at the Johns Hopkins University School of Medicine and the National Institutes of Health have identified a protein in the visual system of mice that appears to be key for stabilizing the body's circadian rhythms by buffering the brain's response to light.

28 Dec 2023

GFH009 disrupts growth signals and triggers apoptosis in hematologic malignancies

A new research paper was published in Oncotarget's Volume 14 on December 20, 2023, entitled, "The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies."

28 Dec 2023

Angelica gigas extract emerges as a potential treatment for vascular disease

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction."

28 Dec 2023

$Lisocabtagene maraleucel: A cost-effective second-line treatment for relapsed/refractory DLBCL$

Lisocabtagene maraleucel: A cost-effective second-line treatment for relapsed/refractory DLBCL

Lisocabtagene maraleucel (liso-cel), a CAR T-cell therapy, is a cost effective second line treatment for relapsed and refractory (hard to treat) diffuse large B-cell lymphoma (r/r DLBCL), according to a study published today in Blood Advances.

28 Dec 2023

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

Brigham researchers' findings from next-generation sequencing suggest that revising current cancer care guidelines could allow approximately 6,000 more patients in the U.S. to benefit from immunotherapy treatment each year

28 Dec 2023

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at the first COVID-19 symptoms, due to the weakening of innate antiviral immunity, leading to delayed viral clearance and adverse outcomes in severe viral pneumonias.

28 Dec 2023

Plant-based fats and proteins shine in low-carb weight management

Low-carbohydrate diets comprised mostly of plant-based proteins and fats with healthy carbohydrates such as whole grains were associated with slower long-term weight gain than low-carbohydrate diets comprised mostly of animal proteins and fats with unhealthy carbohydrates like refined starches, according to a new study led by Harvard T.H. Chan School of Public Health.

27 Dec 2023

Your unique microbiome may be used to improve and personalize your future medical experience

Study explores the potential of microbiomes in personalized medicine, focusing on diagnostics, precision therapy, and the challenges in implementing microbiome-based interventions.

27 Dec 2023

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Research delves into the complex roles of neutrophils in inflammatory bowel disease (IBD), exploring their diverse functions and interactions with the gut microbiota and emphasizing the need for targeted therapies based on these insights.

27 Dec 2023

Common inflammation pathway turns anthrax toxin into killer

Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the cardiovascular system.

26 Dec 2023

Visual-motor illusion enhances motor performance and early-stage learning

Researchers from Tokyo Metropolitan University showed that visual aids which create the illusion of movement, like a screen placed in front of one's hand showing the hand move, can improve motor performance and the early stages of motor learning.

26 Dec 2023

AANEM to host the neuromuscular fellowship match again in 2024

The American Association of Neuromuscular &Electrodiagnostic Medicine (AANEM) is excited to host the neuromuscular (NM) fellowship match again in 2024.

26 Dec 2023

Gut microbiome diversity predicts cognitive function and brain structure in healthy children

Emerging evidence implicates the gut microbiome in cognitive outcomes and neurodevelopmental disorders, but the influence of gut microbial metabolism on typical neurodevelopment has not been explored in detail.

26 Dec 2023

Study: Cuddling during sleep comes at a cost, even for mice

If you’re having trouble sleeping, perhaps contact with a bedmate is causing the problem, say University of Michigan researchers.

26 Dec 2023

Citrus supplement may ease knee swelling and pain after surgery

For patients undergoing total knee arthroplasty (TKA), treatment with diosmin – a flavonoid supplement derived from citrus fruits –reduced swelling of the knee and leg and some measures of associated pain can be achieved, reports a clinical trial in The Journal of Bone & Joint Surgery.

22 Dec 2023

Brain injury markers found in the blood months after COVID-19 infection

A new study published today (22 December 2023) in Nature Communications details that markers of brain injury are present in the blood many months after COVID-19 infection, despite inflammation blood tests being normal.

22 Dec 2023

New family of polymers can kill bacteria without inducing antibiotic resistance

Antibiotic-resistant bacteria have become a rapidly growing threat to public health. Each year, they account for more than 2.8 million infections, according to the U.S. Centers for Disease Control and Prevention.

22 Dec 2023

Medical Science News

Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

Microbial decoration enhances drug delivery specificity and safety

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

'Visual system' protein appears to be key for stabilizing the body's circadian rhythms

GFH009 disrupts growth signals and triggers apoptosis in hematologic malignancies

Angelica gigas extract emerges as a potential treatment for vascular disease

Lisocabtagene maraleucel: A cost-effective second-line treatment for relapsed/refractory DLBCL

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Plant-based fats and proteins shine in low-carb weight management

Your unique microbiome may be used to improve and personalize your future medical experience

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Common inflammation pathway turns anthrax toxin into killer

Visual-motor illusion enhances motor performance and early-stage learning

AANEM to host the neuromuscular fellowship match again in 2024

Gut microbiome diversity predicts cognitive function and brain structure in healthy children

Study: Cuddling during sleep comes at a cost, even for mice

Citrus supplement may ease knee swelling and pain after surgery

Brain injury markers found in the blood months after COVID-19 infection

New family of polymers can kill bacteria without inducing antibiotic resistance

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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