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NEBioCalculator: New online tool offers support for molecular biology experiments

NEBioCalculator, a new online "conversions and calculations" tool developed by New England Biolabs, offers bench-side support for molecular biology experimental planning.

From New England Biolabs 29 Jan 2014

Biologists identify protein targets for next-generation of anti-HIV drugs

People infected with the Human Immunodeficiency Virus (HIV) can stave off the symptoms of AIDS thanks to drug cocktails that mainly target three enzymes produced by the virus, but resistant strains pop up periodically that threaten to thwart these drug combos.

29 Jan 2014

Study: Genetic mutations in titin gene can cause skeletal muscle disease

A University of Arizona doctoral candidate has shown for the first time that genetic mutations in the titin gene can cause skeletal muscle myopathy, a disease in which muscle fibers do not function properly, resulting in muscle weakness.

29 Jan 2014

New research finds similarity in organization of regions of brain in humans and monkeys

New research suggests a surprising degree of similarity in the organization of regions of the brain that control language and complex thought processes in humans and monkeys.

29 Jan 2014

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

In recent years, mutations in two metabolic enzymes, isocitrate dehydrogenase-1 and 2 (IDH1 and IDH2), have been identified in approximately 20 percent of all acute myeloid leukemias (AML). As a result, mutant IDH proteins have been proposed as attractive drug targets for this common form of adult leukemia.

29 Jan 2014

Phasefocus reports on new ptychography paper published in Nature Scientific Reports

Cell imaging often relies on synthetic or genetic fluorescent labels, to provide contrast which can be far from ideal for imaging cells in their in vivo state. We report on the biological application of a label-free, high contrast microscopy technique known as ptychography, in which the image producing step is transferred from the microscope lens to a high-speed phase retrieval algorithm.

From Phase Focus Limited 28 Jan 2014

BD announces commercial availability of CE-marked PAXgene Blood DNA Tube in Europe

BD, a leading global medical technology company, today announced the commercial availability of the CE-marked PAXgene Blood DNA Tube in Europe. The PAXgene Blood DNA Tube is the first blood collection tube designed specifically for in vitro diagnostic (IVD) genomic DNA testing. The product was developed by PreAnalytiX GmbH, a joint venture between BD and QIAGEN.

From BD (Becton, Dickinson and Company) 28 Jan 2014

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

In normal development, all cells turn off genes they don’t need, often by attaching a chemical methyl group to the DNA, a process called methylation. Historically, scientists believed methyl groups could only stick to a particular DNA sequence: a cytosine followed by a guanine, called CpG. But in recent years, they have been found on other sequences, and so-called non-CpG methylation has been found in stem cells, and in neurons in the brain.

28 Jan 2014

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

If the content of many a situation comedy, not to mention late-night TV advertisements, is to be believed, there's an epidemic of balding men, and an intense desire to fix their follicular deficiencies.

28 Jan 2014

Researchers create vaginal cream using silver nanoparticles to control transmition of HIV

The product has proven efficiency in lab tests, although clinical trials are yet to be performed. After discovering that silver nanoparticles are capable of blocking the entry of Human Immunodeficiency Virus (HIV) into the organism, a group of researchers from the University of Texas, in collaboration with Humberto Lara Villegas, specialist in nanoparticles and virology from the University of Monterrey, Mexico (UDEM), create a vaginal cream to control the transmition of the virus.

28 Jan 2014

Positive correlation between white matter quality and addition and multiplication proficiency

A new study led by Professor Bert De Smedt (Faculty of Psychology and Educational Sciences, KU Leuven) has found that healthy 12-year-olds who score well in addition and multiplication have higher-quality white matter tracts.

28 Jan 2014

New modular structures 'glued' with DNA to deliver cancer medications

A team of researchers at the University of Toronto has discovered a method of assembling "building blocks" of gold nanoparticles as the vehicle to deliver cancer medications or cancer-identifying markers directly into cancerous tumors.

28 Jan 2014

Researchers develop valid humanized model for facioscapulohumeral muscular dystrophy

Researchers at the Kennedy Krieger Institute recently announced study findings showing the successful development of a humanized preclinical model for facioscapulohumeral muscular dystrophy (FSHD), providing scientists with a much needed tool to accelerate novel therapeutic research and development.

28 Jan 2014

Temple University Hospital to test multilayer stent in patients suffering from aortic aneurysm

Temple University Hospital (TUH) could be among the first U.S.-based hospitals to test a new device known as a multilayer stent in patients suffering from aortic aneurysm, a condition characterized by the formation of a potentially life-threatening bulge in the aorta.

28 Jan 2014

Researchers discover protein required for growth of hair-like structures on cell surfaces

A team of researchers from Penn State University and the University of California has discovered a protein that is required for the growth of tiny, but critical, hair-like structures called cilia on cell surfaces.

28 Jan 2014

Study provides possible clue to high rate of preterm labor after human fetal surgery

As a fetal surgeon at UC San Francisco, Tippi MacKenzie, MD, has long known that conducting surgery on a fetus to correct a problems such as spina bifida often results in preterm labor and premature birth.

28 Jan 2014

Novel brain-scanning technique maps flow of visual information in brain with unique accuracy

Every time you open your eyes, visual information flows into your brain, which interprets what you're seeing. Now, for the first time, MIT neuroscientists have noninvasively mapped this flow of information in the human brain with unique accuracy, using a novel brain-scanning technique.

28 Jan 2014

Researchers discover unusually large bacteriophage that infects anthrax bacterium

From a zebra carcass on the plains of Namibia in Southern Africa, an international team of researchers has discovered a new, unusually large virus (or bacteriophage) that infects the bacterium that causes anthrax.

28 Jan 2014

Study to evaluate connections between brain networks and religious thought

Building on previous evidence showing that religious belief involves cognitive activity that can be mapped to specific brain regions, a new study has found that causal, directional connections between these brain networks can be linked to differences in religious thought.

28 Jan 2014

Silk and diamonds could provide novel technique for biological imaging, drug delivery

Silk and diamonds aren't just for ties and jewelry anymore. They're ingredients for a new kind of tiny glowing particle that could provide doctors and researchers with a novel technique for biological imaging and drug delivery.

28 Jan 2014

Medical Science News

NEBioCalculator: New online tool offers support for molecular biology experiments

Biologists identify protein targets for next-generation of anti-HIV drugs

Study: Genetic mutations in titin gene can cause skeletal muscle disease

New research finds similarity in organization of regions of brain in humans and monkeys

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

Phasefocus reports on new ptychography paper published in Nature Scientific Reports

BD announces commercial availability of CE-marked PAXgene Blood DNA Tube in Europe

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

Researchers create vaginal cream using silver nanoparticles to control transmition of HIV

Positive correlation between white matter quality and addition and multiplication proficiency

New modular structures 'glued' with DNA to deliver cancer medications

Researchers develop valid humanized model for facioscapulohumeral muscular dystrophy

Temple University Hospital to test multilayer stent in patients suffering from aortic aneurysm

Researchers discover protein required for growth of hair-like structures on cell surfaces

Study provides possible clue to high rate of preterm labor after human fetal surgery

Novel brain-scanning technique maps flow of visual information in brain with unique accuracy

Researchers discover unusually large bacteriophage that infects anthrax bacterium

Study to evaluate connections between brain networks and religious thought

Silk and diamonds could provide novel technique for biological imaging, drug delivery

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

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