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Researchers reveal mechanism behind persistent bacteria

The mechanism by which some bacteria are able to survive antibacterial treatment has been revealed for the first time by Hebrew University of Jerusalem researchers. Their work could pave the way for new ways to control such bacteria.

31 Dec 2013

Melatonin plays major role in pain transmission

Accumulating research indicates that melatonin has a major role in pain transmission and has an ultra-sensitizing effect. Dr. Fang Huang and colleagues from Sun Yat-sen University in China for the first time located the distribution of melatonin receptor 1 in the caudal spinal trigeminal nucleus.

31 Dec 2013

Study explains how nicotine exploits body's cellular machinery to promote addiction

A study in The Journal of General Physiology helps explain how nicotine exploits the body's cellular machinery to promote addiction. The findings could lead to new therapies to help people quit smoking.

30 Dec 2013

Study: Cholesterol levels linked to early signs of Alzheimer's disease in the brain

High levels of "good" cholesterol and low levels of "bad" cholesterol are correlated with lower levels of the amyloid plaque deposition in the brain that is a hallmark of Alzheimer's disease, in a pattern that mirrors the relationship between good and bad cholesterol in cardiovascular disease, UC Davis researchers have found.

30 Dec 2013

Researchers provide new insights into how common cold virus infects

On average, each of us catches a cold two to three times a year. However, how the common cold virus actually infects us is only partly understood. Researchers from the Max F. Perutz Laboratories of the Medical University of Vienna and the University of Vienna, in collaboration with two Spanish groups, have now provided new insights into this process.

30 Dec 2013

Research could pave way for more effective treatments for bacterial infections

30 Dec 2013

Ancient Peru healers drilled holes in the cranium for treatment

Cranial surgery is tricky business, even under 21st-century conditions (think aseptic environment, specialized surgical instruments and copious amounts of pain medication both during and afterward).

28 Dec 2013

Scientists obtain detailed molecular structure of member of Tet family of enzymes

Scientists have obtained the first detailed molecular structure of a member of the Tet family of enzymes.

28 Dec 2013

Combination of NGF microspheres and chitosan conduits exhibit better effects in repairing facial nerve injury

The chitosan molecule can promote nerve cell adherence and growth along the surface of the material. It can enhance the adherence and influx of Schwann cells, thus encouraging the growth of axons.

28 Dec 2013

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

We are fundamentally dependent on the presence of copper in the cells of the body. Copper is actually part of the body's energy conversion and protective mechanisms against oxygen radicals, as well as part of the immune system, and it also has great importance for the formation of e.g. hormones and neurotransmitters.

28 Dec 2013

Cancer immunotherapy named 2013 Breakthrough of the Year by journal Science

Detect. Destroy. Remember. The mantra of the immune system's relentless campaign against infectious invaders and the body's own abnormal cells finally is applying to cancer in meaningful ways.

28 Dec 2013

Unprecedented, atom-scale simulation of G protein-coupled receptor site's transformation

Roughly 40 percent of all medications act on cells' G protein-coupled receptors (GPCRs). One of these receptors, beta 2 adrenergic receptor site (B2AR), naturally transforms between two base configurations; knowing the precise location of each of approximately 4,000 atoms is crucial for ensuring a snug fit between it and the drug.

28 Dec 2013

Rho-associated protein kinase regulates hippocampal neurite growth, microtubule formation

Rho-associated protein kinase is an essential regulator of cytoskeletal dynamics during the process of neurite extension. However, whether Rho kinase regulates microtubule remodeling or the distribution of adhesive proteins to mediate neurite outgrowth remains unclear.

28 Dec 2013

Study shows beneficial effects of normobaric oxygen on cerebral ischemic injury

Normobaric oxygen has the rapid and non-invasive characteristics and may have therapeutic effects on ischemic/hypoxic disease.

28 Dec 2013

Stroke rehabilitation researchers report improvement in spatial neglect with prism adaptation therapy

Stroke rehabilitation researchers report improvement in spatial neglect with prism adaptation therapy. This new study supports behavioral classification of patients with spatial neglect as a valuable tool for assigning targeted, effective early rehabilitation.

27 Dec 2013

Researchers explore ways to overcome transplant rejection

Given that 10.5 % of patients who receive a transplant reject the new organ, researchers at the Center of Research and Advanced Studies of the National Polytechnic Institute (Cinvestav) are working in the design of a tool capable of preventing this problem.

27 Dec 2013

MitoQ antioxidant reverses MS-like disease in animal

Researchers at Oregon Health & Science University have discovered that an antioxidant designed more than a dozen years ago to fight damage within human cells significantly helps symptoms in mice that have a multiple sclerosis-like disease.

27 Dec 2013

Researchers study health consequences of RTE proliferation that occurs in aging tissues

The genomes of organisms from humans to corn are replete with "parasitic" strands of DNA that, when not suppressed, copy themselves and spread throughout the genome, potentially affecting health. Earlier this year Brown University researchers found that these "retrotransposable elements" were increasingly able to break free of the genome's control in cultures of human cells.

27 Dec 2013

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Substance P and calcitonin gene-related peptide are the main neuropeptides in peripheral nerve ganglia, which can anterogradely transmit nociceptive information to the central nervous system.

27 Dec 2013

Stem cell-based gene therapy shows long-term outcomes for treatment of genetic skin diseases

Stem cell-based gene therapy holds promise for the treatment of devastating genetic skin diseases, but the long-term clinical outcomes of this approach have been unclear.

27 Dec 2013

Medical Science News

Researchers reveal mechanism behind persistent bacteria

Melatonin plays major role in pain transmission

Study explains how nicotine exploits body's cellular machinery to promote addiction

Study: Cholesterol levels linked to early signs of Alzheimer's disease in the brain

Researchers provide new insights into how common cold virus infects

Research could pave way for more effective treatments for bacterial infections

Ancient Peru healers drilled holes in the cranium for treatment

Scientists obtain detailed molecular structure of member of Tet family of enzymes

Combination of NGF microspheres and chitosan conduits exhibit better effects in repairing facial nerve injury

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

Cancer immunotherapy named 2013 Breakthrough of the Year by journal Science

Unprecedented, atom-scale simulation of G protein-coupled receptor site's transformation

Rho-associated protein kinase regulates hippocampal neurite growth, microtubule formation

Study shows beneficial effects of normobaric oxygen on cerebral ischemic injury

Stroke rehabilitation researchers report improvement in spatial neglect with prism adaptation therapy

Researchers explore ways to overcome transplant rejection

MitoQ antioxidant reverses MS-like disease in animal

Researchers study health consequences of RTE proliferation that occurs in aging tissues

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Stem cell-based gene therapy shows long-term outcomes for treatment of genetic skin diseases

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

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