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Researchers explore how certain molecular signaling pathways control aging across all species

Fruit flies are notoriously short-lived but scientists interested in the biology of aging in all animals have begun to understand why some fruit flies live longer than others. They have documented a direct association between insulin and life span, for example, and have observed a tradeoff between prolific reproduction and longevity. A new study, which may have broad implications across species, ties those findings more closely together by tracing an insulin signaling cascade through to protein quality control in muscle tissue and shortened life span.

18 Nov 2013

Researchers develop novel system to image worm brain activity

A research team at Worcester Polytechnic Institute and The Rockefeller University in New York has developed a novel system to image brain activity in multiple awake and unconstrained worms. The technology, which makes it possible to study the genetics and neural circuitry associated with animal behavior, can also be used as a high-throughput screening tool for drug development targeting autism, anxiety, depression, schizophrenia, and other brain disorders.

18 Nov 2013

Study: New device helps people who lost vision due to blinding genetic disease

Research presented today at the 117th Annual Meeting of the American Academy of Ophthalmology shows promising data about a device that helps people who have lost their vision due to a blinding genetic disease to recognize common objects.

18 Nov 2013

Researchers develop more accurate way to calculate "bad" cholesterol

Johns Hopkins researchers have developed a more accurate way to calculate low-density lipoprotein (LDL) cholesterol, the so-called "bad" form of blood fat that can lead to hardening of the arteries and increase the risk of heart attack and stroke.

18 Nov 2013

Scientists describe interplay of four molecules that trigger, govern antibody production in immune cells

Australian scientists have described an exquisitely balanced interplay of four molecules that trigger and govern antibody production in immune cells. As well as being an important basic science discovery, it helps explain why people with mutations in any one of the associated genes cannot fight infection effectively, and develop rare and crippling immunodeficiency disorders.

18 Nov 2013

Researchers generate three-dimensional kidney structures from human stem cells

Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology.

18 Nov 2013

Scientists discover gene associated with high risk of severe childhood asthma.

An international scientific team has discovered a gene associated with a high risk of severe childhood asthma. The specific gene variant may be an actual cause of this form of asthma, a leading cause of hospitalization in young children.

17 Nov 2013

Mount Sinai biologist wins NIH Director's New Innovator Awards for High-Risk, High Reward Research

Arvin Dar, PhD, structural and chemical biologist in oncological sciences at the Icahn School of Medicine at Mount Sinai, is one of 41 national recipients of the prestigious National Institutes of Health (NIH) Director's New Innovator Awards for High-Risk, High Reward Research. The award will support Dar's research into Ras-dependent cancers, specifically investigating how to combat mutations in Ras, a protein implicated in at least one of every five cancers.

16 Nov 2013

Research shows superiority of whey protein

As science continues to support the role of protein in building and maintaining lean muscle, maintaining weight and aging healthy, consumers are embracing the important role of protein in the diet. But not all proteins are created equal and it turns out that protein quality really does matter.

16 Nov 2013

Heidelberg scientists identify protein motifs that influence gene silencing

Bioscientists at Heidelberg University have studied the function of certain proteins, known as Argonaute (Ago) proteins, in the process of gene regulation. They sought to understand why only the Ago2 protein is able to target and directly turn off genes in humans, while the closely related Ago3 protein is not.

16 Nov 2013

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

A protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells, according to new research out of the University of Minnesota. The findings could explain why nearly half of all patients infected with the AIDS virus experience some level of neurocognitive impairment.

16 Nov 2013

Researchers explain new function of 2 key molecules involved in tumor progression

Researchers from IMIM (Hospital del Mar Medical Research Institute) lead by Dr. Sandra Peir- have described a new function for two key molecules involved in tumor progression.

16 Nov 2013

Genome sequence data indicates that common species of malaria may evolve to become bigger threat

Provocative new research shows that the Plasmodium vivax parasite, responsible for nearly 20 million cases of malaria in 2010, may be "rapidly evolving" to overcome the natural resistance conferred by a blood type found in millions of Africans, scientists reported today at the annual meeting of the American Society of Tropical Medicine and Hygiene.

16 Nov 2013

Study finds fruit juices could potentially be good carriers of probiotics

Probiotics are often added to products in order provide additional nutritional benefits to the consumer, thus making them "functional foods." A new study in the Journal of Food Science, published by the Institute of Food Technologists (IFT), found that fruit juices could potentially be good carriers for two different kinds of probiotics.

16 Nov 2013

Carl-Philipp Heisenberg group detects mechanism in cell division relevant for closing wounds

Spreading of the epithelial cell layer is fundamental for epithelial closure and wound healing, as well as for embryonic development. The challenge presented here is that the cell layer needs to increase in surface area, but nevertheless maintain its integrity.

16 Nov 2013

Reengineered protein may lead to safer, more effective retroviral gene therapy

A fusion protein engineered by researchers at KU Leuven combining proteins active in HIV and Moloney murine leukaemia virus (MLV) replication may lead to safer, more effective retroviral gene therapy.

16 Nov 2013

Mediterranean sofrito linked with low incidence of cardiovascular effects

The Mediterranean sofrito, the typical tomato-based sauce that seasons many dishes, has a high concentration of polyphenols which are associated with a low incidence of cardiovascular effects.

16 Nov 2013

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

Skin provides a first line of defense against viruses, bacteria and parasites that might otherwise make people ill. When an injury breaks that barrier, a systematic chain of molecular signaling launches to close the wound and re-establish the skin's layer of protection.

16 Nov 2013

GoInformatics, TeselaGen form strategic partnership to offer cutting-edge biodesign automation tools

GoInformatics and TeselaGen have announced a strategic partnership to offer a state-of-the-art Biological Design Automation and Scientific Data Management platform. With a secure repository to collect, organize, and store research information, the integrated cloud-based platform will enable scientists advance their research at a much faster pace.

16 Nov 2013

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

The Joint Center for Cancer Precision Medicine, a collaborative initiative among Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, and the Broad Institute of MIT and Harvard, has been established to create "precision medicine treatment pathways" for patients with advanced cancers and to speed the development of personalized therapies.

16 Nov 2013

Medical Science News

Researchers explore how certain molecular signaling pathways control aging across all species

Researchers develop novel system to image worm brain activity

Study: New device helps people who lost vision due to blinding genetic disease

Researchers develop more accurate way to calculate "bad" cholesterol

Scientists describe interplay of four molecules that trigger, govern antibody production in immune cells

Researchers generate three-dimensional kidney structures from human stem cells

Scientists discover gene associated with high risk of severe childhood asthma.

Mount Sinai biologist wins NIH Director's New Innovator Awards for High-Risk, High Reward Research

Research shows superiority of whey protein

Heidelberg scientists identify protein motifs that influence gene silencing

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

Researchers explain new function of 2 key molecules involved in tumor progression

Genome sequence data indicates that common species of malaria may evolve to become bigger threat

Study finds fruit juices could potentially be good carriers of probiotics

Carl-Philipp Heisenberg group detects mechanism in cell division relevant for closing wounds

Reengineered protein may lead to safer, more effective retroviral gene therapy

Mediterranean sofrito linked with low incidence of cardiovascular effects

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

GoInformatics, TeselaGen form strategic partnership to offer cutting-edge biodesign automation tools

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

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