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Functional biomarker could help guide treatment of patients with BRAF-mutant melanomas

A functional biomarker that can predict whether BRAF-mutant melanomas respond to drugs targeting BRAF could help guide the treatment of patients with these cancers, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19 - 23.

23 Oct 2013

New MDx prototype platform can detect BRAF V600 mutations in 90 minutes

A new diagnostic platform to detect BRAF mutations in melanoma and other cancer types is faster and more accurate compared with the standard method currently used in clinics, and this could help accelerate diagnosis and treatment, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

23 Oct 2013

U of T researchers develop method to screen human stem cells

University of Toronto researchers have developed a method that can rapidly screen human stem cells and better control what they will turn into. The technology could have potential use in regenerative medicine and drug development. Findings are published in this week's issue of the journal Nature Methods.

23 Oct 2013

Number sense in infancy predicts mathematical abilities in childhood

Babies who are good at telling the difference between large and small groups of items even before learning how to count are more likely to do better with numbers in the future, according to new research from the Duke Institute for Brain Sciences.

23 Oct 2013

Study evaluates role of enteroviruses in human type 1 diabetes

Type 1 diabetes is a disease caused by the destruction of the insulin-producing cells in the pancreas. It is often diagnosed in childhood and requires life-long treatment with daily insulin injections. It is associated with an increased risk for long-term complications which decrease the quality of life and average life-expectancy.

23 Oct 2013

Climate change associated with increased mortality, especially during extremely hot periods

The increased temperatures caused by ongoing climate change in Stockholm, Sweden between 1980 and 2009 caused 300 more premature deaths than if the temperature increase did not take place.

23 Oct 2013

Clinical trial to investigate if vitamin D supplement helps prevent type 2 diabetes

Researchers have begun the first definitive, large-scale clinical trial to investigate if a vitamin D supplement helps prevent or delay type 2 diabetes in adults who have prediabetes, who are at high risk for developing type 2. Funded by the National Institutes of Health, the study is taking place at about 20 study sites across the United States.

23 Oct 2013

Illumina announces launch of TruGenome Undiagnosed Disease Test

Illumina, Inc. today announced the launch of its TruGenome Undiagnosed Disease Test provided by the CLIA-certified, CAP-accredited Illumina Clinical Services Laboratory.

From Illumina, Inc. 22 Oct 2013

Clinical trial to determine whether vitamin D helps prevent or delay development of type 2 diabetes

UT Southwestern Medical Center researchers are seeking 150 to 200 adults to take part in the local arm of a major national clinical trial that will investigate whether vitamin D helps prevent or delay development of type 2 diabetes.

22 Oct 2013

Study finds no evidence that stem cell therapy improves vision for children with ONH

A study performed at Children's Hospital Los Angeles found no evidence that stem cell therapy improves vision for children with optic nerve hypoplasia. Their results are reported in the Journal of the American Association for Pediatric Ophthalmology and Strabismus.

22 Oct 2013

Buck Institute finds link between ApoE4 and anti-aging protein targeted by resveratrol in red wine

he major genetic risk factor for Alzheimer's disease (AD), present in about two-thirds of people who develop the disease, is ApoE4, the cholesterol-carrying protein that about a quarter of us are born with. But one of the unsolved mysteries of AD is how ApoE4 causes the risk for the incurable, neurodegenerative disease.

22 Oct 2013

Learning mentally challenging skills may help improve memory in older people, says study

Seniors who step outside their comfort zones could be enhancing their memories beyond those who stick with what they know.

22 Oct 2013

Nanopharmaceutical drug shows promise for cancers that resist antiangiogenic drugs

The nanopharmaceutical drug CRLX101 is showing promise as a potential new treatment for cancers that develop resistance to antiangiogenic drugs and radiation therapy, according to clinical trial results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19 - 23.

22 Oct 2013

Research: Low levels of vitamin D appear to increase child's risk of anemia

Low levels of the "sunshine" vitamin D appear to increase a child's risk of anemia, according to new research led by investigators at the Johns Hopkins Children's Center. The study, published online Oct. 10 in the Journal of Pediatrics, is believed to be the first one to extensively explore the link between the two conditions in children.

22 Oct 2013

Study opens doors to novel treatments for aggressive brain cancer

Ludwig researchers have elucidated a key mechanism by which cancer cells change how they metabolize glucose to generate the energy and raw materials required to sustain runaway growth.

22 Oct 2013

CUMC develops new technique that uses patient's own cells to grow new hair

Researchers at Columbia University Medical Center (CUMC) have devised a hair restoration method that can generate new human hair growth, rather than simply redistribute hair from one part of the scalp to another.

22 Oct 2013

Personalis launches early access program to Personalis ACE Clinical Exome

Personalis, Inc., the leading provider of advanced medical exome and genome sequencing and interpretation services today announced the launch of an early access program to the Personalis ACE Clinical Exome, a single test that integrates enhanced exome sequencing with genome-wide structural variant detection to increase diagnostic yield.

21 Oct 2013

Medical Science News

Functional biomarker could help guide treatment of patients with BRAF-mutant melanomas

New MDx prototype platform can detect BRAF V600 mutations in 90 minutes

U of T researchers develop method to screen human stem cells

Number sense in infancy predicts mathematical abilities in childhood

Study evaluates role of enteroviruses in human type 1 diabetes

Climate change associated with increased mortality, especially during extremely hot periods

Clinical trial to investigate if vitamin D supplement helps prevent type 2 diabetes

Illumina announces launch of TruGenome Undiagnosed Disease Test

Clinical trial to determine whether vitamin D helps prevent or delay development of type 2 diabetes

Study finds no evidence that stem cell therapy improves vision for children with ONH

Buck Institute finds link between ApoE4 and anti-aging protein targeted by resveratrol in red wine

Learning mentally challenging skills may help improve memory in older people, says study

Nanopharmaceutical drug shows promise for cancers that resist antiangiogenic drugs

Research: Low levels of vitamin D appear to increase child's risk of anemia

Study opens doors to novel treatments for aggressive brain cancer

CUMC develops new technique that uses patient's own cells to grow new hair

Personalis launches early access program to Personalis ACE Clinical Exome

Research paper published by Scientific Reports details the efficacy of n3D's Apple iPhone app

UCLA study uncovers biological clock that may shed light on why our bodies age

New collaborative project aims to discover genes underlying rare genetic diseases

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

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