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Genomic instability in CFS is associated with less favorable outcome in patients with CaP

Detailed evaluation of a prostate cancer tumor biopsy may predict treatment outcomes for image-guided radiation therapy (IGRT) or surgery for prostate cancer, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 55th Annual Meeting.

27 Sep 2013

Scientists unravel secrets of mechanism that snips our genes

Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.

27 Sep 2013

New imaging technique reveals first 3D pictures of chromosome structure

A new method for visualising chromosomes is painting a truer picture of their shape, which is rarely like the X-shaped blob of DNA most of us are familiar with.

27 Sep 2013

Optic flow enables perception despite blur image

Blurred images that are unidentifiable as still pictures become understandable once the images are set in motion. That's because of a phenomenon called "optic flow"—which may be especially relevant as a source of visual information in people with low vision, reports a study 'With an Eye to Low Vision: Optic Flow Enables Perception Despite Image Blur' in the October issue of Optometry and Vision Science official journal of the American Academy of Optometry.

27 Sep 2013

Study indicates that RNA translation is dictated by translational hotspots

Protein synthesis in the extensions of nerve cells, called dendrites, underlies long-term memory formation in the brain, among other functions. "Thousands of messenger RNAs reside in dendrites, yet the dynamics of how multiple dendrite messenger RNAs translate into their final proteins remain elusive," says James Eberwine, PhD, professor of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, and co-director of the Penn Genome Frontiers Institute.

27 Sep 2013

Genes in mitochondria shape each person's risk for heart disease and diabetes

Genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's risk for heart disease and diabetes, according to a study published recently by researchers at the University of Alabama at Birmingham in the Biochemical Journal.

27 Sep 2013

Scientists discover critical regulator for directing pluripotent stem cells to make blood-forming stem cells

Stem cell scientists have moved one step closer to producing blood-forming stem cells in a Petri dish by identifying a key regulator controlling their formation in the early embryo, shows research published online today in Cell.

27 Sep 2013

Intestinal mucus potentially improves life of people suffering from inflammatory bowel disease

Researchers at Institut Hospital del Mar d'Investigacions M-diques (IMIM) in Barcelona, in collaboration with the Icahn School of Medicine at Mount Sinai in New York and other U.S. Institutions, have found that intestinal mucus not only acts as a physical barrier against commensal bacteria and dietary antigens, but also prevents the onset of inflammatory reactions against these agents.

27 Sep 2013

Folic acid deficiency may be associated with multi-generational impact on health

Folic acid deficiency can cause severe health problems in offspring, including spina bifida, heart defects and placental abnormalities. A study out today reveals that a mutation in a gene necessary for the metabolism of folic acid not only impacts the immediate offspring but can also have detrimental health effects on the next several generations.

27 Sep 2013

TSRI scientists discover process by which special immune cells in skin help heal wounds

Scientists at The Scripps Research Institute (TSRI) have discovered an important process by which special immune cells in the skin help heal wounds. They found that these skin-resident immune cells function as "first responders" to skin injuries in part by producing the molecule known as interleukin-17A (IL-17A), which wards off infection and promotes wound healing.

27 Sep 2013

Study shows certain brain cells play critical role in anorexia, bulimia, and binge eating disorder

Sixty years ago scientists could electrically stimulate a region of a mouse's brain causing the mouse to eat, whether hungry or not. Now researchers from UNC School of Medicine have pinpointed the precise cellular connections responsible for triggering that behavior.

27 Sep 2013

Scientists study genetic factors involved in complex diseases

Although heavily studied, the specific genetic causes of "complex diseases," a category of disorders which includes autism, diabetes and heart disease, are largely unknown due to byzantine genetic and environmental interactions.

27 Sep 2013

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

The mood changes of a 'Jekyll-and-Hyde' protein, which sometimes boosts tumour cell growth and at other times suppresses it, have been explained in a new study led by Oxford University researchers.

27 Sep 2013

Experiments with neutrons show antidepressant lithium accumulates strongly in white matter of the brain

At present lithium is most popular for its use in rechargeable batteries. But for decades now, lithium has also been used to treat various psychological diseases such as depressions, manias and bipolar disorders. But, the exact biological mode of action in certain brain regions has hardly been understood. It is well known that lithium lightens moods and reduces aggression potential.

27 Sep 2013

Research on bone-derived hormone could lead to new treatments for memory loss, depression

Researchers from Columbia University Medical Center (CUMC) have found that the skeleton, acting through the bone-derived hormone osteocalcin, exerts a powerful influence on prenatal brain development and cognitive functions such as learning, memory, anxiety, and depression in adult mice.

27 Sep 2013

Ampio Pharmaceuticals announces financing transaction of $25 million

Ampio Pharmaceuticals, Inc. (NYSE MKT: AMPE) today announced a financing transaction that will provide $25 million in gross proceeds to the Company. The financing is a registered direct placement of common stock of the Company.

26 Sep 2013

VolitionRx enters into distribution agreement with Active Motif for NuQ product line

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests for different types of cancer, today entered into an agreement with Active Motif, a leading provider of kits and reagents to enable epigenetics research.

26 Sep 2013

Pittcon to exhibit at BioConference Live’s “Cancer: Research, Discovery and Therapeutics” online-only event

Pittcon is pleased to announce it will be exhibiting at the next BioConference Live virtual event. BioConference Live, the largest producer of online-only conferences focused on life sciences, laboratory animal sciences and clinical diagnostics, has announced the upcoming “Cancer: Research, Discovery and Therapeutics” online-only conference.

26 Sep 2013

Researchers identify mutation in ITGA10 gene that causes chondrodysplasia in dog breeds

Professor Hannes Lohi's research group at the University of Helsinki and Folkhälsan Research Center has identified a mutation in ITGA10 gene, causing chondrodysplasia in two dog breeds, the Norwegian Elkhound and the Karelian Bear Dog.

26 Sep 2013

Study: Fruit and vegetable consumption reduces all-cause mortality

A European study analyzes the relationship between fruit and vegetable consumption and the risk of mortality. As previous research has already suggested, this study concludes that fruit and vegetable consumption reduces all-cause mortality, and especially cardiovascular disease mortality.

26 Sep 2013

Medical Science News

Genomic instability in CFS is associated with less favorable outcome in patients with CaP

Scientists unravel secrets of mechanism that snips our genes

New imaging technique reveals first 3D pictures of chromosome structure

Optic flow enables perception despite blur image

Study indicates that RNA translation is dictated by translational hotspots

Genes in mitochondria shape each person's risk for heart disease and diabetes

Scientists discover critical regulator for directing pluripotent stem cells to make blood-forming stem cells

Intestinal mucus potentially improves life of people suffering from inflammatory bowel disease

Folic acid deficiency may be associated with multi-generational impact on health

TSRI scientists discover process by which special immune cells in skin help heal wounds

Study shows certain brain cells play critical role in anorexia, bulimia, and binge eating disorder

Scientists study genetic factors involved in complex diseases

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

Experiments with neutrons show antidepressant lithium accumulates strongly in white matter of the brain

Research on bone-derived hormone could lead to new treatments for memory loss, depression

Ampio Pharmaceuticals announces financing transaction of $25 million

VolitionRx enters into distribution agreement with Active Motif for NuQ product line

Pittcon to exhibit at BioConference Live’s “Cancer: Research, Discovery and Therapeutics” online-only event

Researchers identify mutation in ITGA10 gene that causes chondrodysplasia in dog breeds

Study: Fruit and vegetable consumption reduces all-cause mortality

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

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