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Drug release of tramadol hydrochloride increases from 1.9 to 7.5 hours by adding Novozymes Biopharma’s Hyasis®

Novozymes Biopharma, part of Novozymes A/S, a world leader in bioinnovation, today announced the release of new findings concerning the effect of Bacillus-derived Hyaluronic Acid (HA) on the drug release of tramadol hydrochloride. The new research is to be presented as a scientific poster at the 2013 Controlled Release Society (CRS) annual meeting, July 21-24, Hawaii, USA.

22 Jul 2013

Bacillus-derived Hyaluronic acid from Novozymes Biopharma, Hyasis®, increases in vitro drug release time from under 10 minutes to approximately 15 hours

An investigation undertaken by Novozymes Biopharma DK has shown that when the corticosteroid dexamethasone is formulated in a cross-linked Hyaluronic acid (HA) hydrogel, the drug’s in vitro release time increases from under 10 minutes to approximately 15 hours. In addition, the in vivo half-life of dexamethasone is shown to plateau with stable dexamethasone concentration up to four hours after injection.

22 Jul 2013

CLAMP: A newly discovered protein that regulates genes

They say a good man is hard to find. Were it not for a newly discovered protein, the X chromosome of a male fruit fly could never be found by a gene-regulating complex that male flies need to develop and survive. And that case is just one example of what the new finding means. More generally, the research provides biologists with a model of how proteins that govern gene transcription find their targets on chromosomes, a process that's essential to healthy cell function and sometimes implicated in disease.

22 Jul 2013

Registration now open for Mushrooms and Health Summit

Registration is now open for the Mushrooms and Health Summit held at the Mayflower Renaissance hotel in Washington D.C. on September 9-10, 2013. The meeting is of interest to scientists, writers and researchers looking to learn and discuss the unique and comprehensive examination of the global research that links mushrooms to today's and future health issues.

22 Jul 2013

Study reveals that Hudson River polluted with antibiotic-resistant bacteria

The risk of catching some nasty germ in the Hudson River just started looking nastier. Disease-causing microbes have long been found swimming there, but now researchers have documented antibiotic-resistant strains in specific spots, from the Tappan Zee Bridge to lower Manhattan.

22 Jul 2013

Scientists find that lipocalin 2 protein disables macrophages in bacterial pneumonia

Macrophages, also known as scavenger cells, play an important role in defending against bacteria and pathogens by activating inflammatory processes. In cases of lung inflammation (pneumonia) caused by pneumococcal bacteria, this important immune response function is hampered and blocked by the protein lipocalin 2.

22 Jul 2013

New stem cell discovery may help scientists replace damaged organs

Stem-cell researchers at UC San Francisco have found a key role for a protein called BMI1 that may help scientists direct the development of tissues to replace damaged organs in the human body.

22 Jul 2013

Implications for treating some common food allergies

Food is an integral part of life; but, for some, it can be harmful. Allergic inflammation caused by inappropriate immune responses to some types of food has become a major public health issue. Over the past ten years, the prevalence of food allergies has increased by nearly 20 percent, affecting an estimated six million people in the U.S.

22 Jul 2013

Monash University researchers provide novel pathways to develop treatments for diseases

Monash University researchers have gained new insight into the early stages of our immune response, providing novel pathways to develop treatments for diseases from multiple sclerosis to cancer.

22 Jul 2013

Gladstone-led study finds underlying mechanisms behind Huntington's disease

Alzheimer's, Huntington's, Parkinson's. Names forever linked to what they represent: diseases that ravage the brain's neurons and leave entire regions to wither and die. These and other so-called neurodegenerative diseases are often associated with the buildup of toxic proteins that lead to the death of neurons.

22 Jul 2013

Quickly clearing out damaged proteins may help prevent neurodegenerative disorders: Study

Recycling is not only good for the environment, it's good for the brain. A study using rat cells indicates that quickly clearing out defective proteins in the brain may prevent loss of brain cells.

22 Jul 2013

Weeds derived from crop plant pose special challenges for modern farming

The evolutionary biologist Stephen Jay Gould once asked whether the living world would be different "if the tape were played twice." If there were a duplicate Earth evolving quietly beside ours, would we observe the emergence of creatures like ourselves and of plants and anaimals familiar to us, or would the cast of characters be entirely different?

22 Jul 2013

Study sheds light on how cells regenerate protective sheaths around nerve fibres in the brain

Multiple sclerosis treatments that repair damage to the brain could be developed thanks to new research.

22 Jul 2013

Vegetation may not protect people from ozone pollution, says new research

During heat waves - when ozone production rises - plants' ozone absorption is curtailed, leaving more pollution in the air, and costing an estimated 460 lives in the UK in the hot summer of 2006.

20 Jul 2013

ACC report helps clinicians optimize appropriate use of noninvasive vascular tests

A new report issued today by the American College of Cardiology (ACC) and developed in collaboration with 10 other leading professional societies provides detailed criteria to help clinicians optimize the appropriate use of certain noninvasive vascular tests when caring for patients with known or suspected disorders of the venous (veins) system.

20 Jul 2013

Structural properties have changed across bacterial families without putting limits on antibiotic resistance

Antibiotic-resistant bacteria have been emerging at an alarming rate. In some of the scariest of these pathogens, the mechanism responsible for the bacteria's ability to defeat antibiotics is a complex protein molecule embedded in the bacterial cell wall -- the enzyme β-lactamase.

20 Jul 2013

Medical Science News

Drug release of tramadol hydrochloride increases from 1.9 to 7.5 hours by adding Novozymes Biopharma’s Hyasis®

Bacillus-derived Hyaluronic acid from Novozymes Biopharma, Hyasis®, increases in vitro drug release time from under 10 minutes to approximately 15 hours

CLAMP: A newly discovered protein that regulates genes

Registration now open for Mushrooms and Health Summit

Study reveals that Hudson River polluted with antibiotic-resistant bacteria

Scientists find that lipocalin 2 protein disables macrophages in bacterial pneumonia

New stem cell discovery may help scientists replace damaged organs

Implications for treating some common food allergies

Monash University researchers provide novel pathways to develop treatments for diseases

Gladstone-led study finds underlying mechanisms behind Huntington's disease

Quickly clearing out damaged proteins may help prevent neurodegenerative disorders: Study

Weeds derived from crop plant pose special challenges for modern farming

Study sheds light on how cells regenerate protective sheaths around nerve fibres in the brain

Vegetation may not protect people from ozone pollution, says new research

ACC report helps clinicians optimize appropriate use of noninvasive vascular tests

Structural properties have changed across bacterial families without putting limits on antibiotic resistance

Listen-and-repeat singing method can improve foreign language learning

Researchers visualize live cell-to-cell communication pathways in bacteria

Brigham and Women's Hospital study examines sustained inattentional blindness in expert observers

CETSA helps scientists determine effectiveness of drugs in the body

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

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