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Researchers discover an important mechanism that regulates proteasome activity

Dysfunction of the ubiquitin-proteasome system (UPS) has been detected in many neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, and certain types of cancer. Such dysfunction is also believed to be related to some degenerative muscle diseases. Researchers at the University of Helsinki, Finland, have now discovered an important mechanism that regulates proteasome activity.

1 Jul 2013

Researchers find fear can increase or decrease ability to discriminate among sounds depending on context

Anyone who's ever heard a Beethoven sonata or a Beatles song knows how powerfully sound can affect our emotions. But it can work the other way as well - our emotions can actually affect how we hear and process sound.

1 Jul 2013

Protein in liver plays a crucial role in mice's pregnancy and human menstrual cycle

A protein first shown to function in the liver plays a crucial role in pregnancy in mice and has a key role in the human menstrual cycle, according to researchers at the University of Montreal. Mice that were genetically engineered not to produce the liver receptor homolog-1 (Lrh-1) molecule were unable to create the uterine conditions necessary for establishing and sustaining pregnancy, resulting in the formation of defective placentas.

1 Jul 2013

Scientists identify neuronal circuits in spinal cord control limb alternation during walking

Scientists at Karolinska Institutet in Sweden have identified the neuronal circuits in the spinal cord of mice that control the ability to produce the alternating movements of the legs during walking.

1 Jul 2013

Research: Systemic dose of dendritic cells prevent rejection in kidney transplantation

A single systemic dose of special immune cells prevented rejection for almost four months in a preclinical animal model of kidney transplantation, according to experts at the University of Pittsburgh School of Medicine.

1 Jul 2013

Tiny RNA molecules work as powerful regulators of immune response in mammals

A team led by scientists at The Scripps Research Institute (TSRI) has identified a family of tiny RNA molecules that work as powerful regulators of the immune response in mammals. Mice who lack these RNA molecules lose their normal infection-fighting ability, whereas mice that overproduce them develop a fatal autoimmune syndrome.

1 Jul 2013

Study shows autophagy blockers play a role in treatment of non-small-cell lung cancer

New research from Rutgers Cancer Institute of New Jersey, Princeton University and other collaborators suggests that inactivation of an essential gene responsible for the cell survival process known as autophagy can suppress the growth of non-small-cell lung cancer tumors and render them more benign.

1 Jul 2013

Biomolecular interactions of nanoparticles can improve drug development, optical sensors and more

In chemical reactions, left and right can make a big difference. A "left-handed" molecule of a particular chemical composition could be an effective drug, while its mirror-image "right-handed" counterpart could be completely inactive.

30 Jun 2013

Synthetic biology technology could lead to new antibiotics, modified protein-generators

Synthetic biology researchers at Northwestern University, working with partners at Harvard Medical School, have for the first time synthesized ribosomes -- cell structures responsible for generating all proteins and enzymes in our bodies -- from scratch in a test tube.

30 Jun 2013

Study shows lymphatic circulatory system may be intimately involved in vascular disorders

The often forgotten lymphatic circulatory system may be intimately involved in vascular disorders, according to a study by researchers from The University of Texas Health Science Center at Houston (UTHealth) and University of Michigan. Their research was reported recently in the Proceedings of the National Academy of Sciences.

30 Jun 2013

Researchers develop new drug delivery systems to treat cancer by blocking signaling receptor

A cardiac hormone signaling receptor abundantly expressed both in inflamed tissues and cancers appears to recruit stem cells that form the blood vessels needed to feed tumor growth, reports a new study by scientists at the University of South Florida Nanomedicine Research Center.

30 Jun 2013

Ecology, evolution of infectious diseases to be highlighted at ESA's annual meeting

West Nile virus, Lyme disease and hantavirus. All are infectious diseases spreading in animals and in people. Is human interaction with the environment somehow responsible for the increase in these diseases? The ecology and evolution of infectious diseases will be highlighted at two symposia at the Ecological Society of America's annual meeting, held from Aug. 5-9 in Minneapolis, Minn.

29 Jun 2013

Low doses of arsenic and estrogen can cause cancer in prostate cells, study finds

Science knows that arsenic and estrogen can cause cancer. At certain very low levels, the chemicals offer little to no threats to human health.

29 Jun 2013

Berkeley Lab scientists create atomic-scale structure of ribosome

This may look like a tangle of squiggly lines, but you're actually looking at a molecular machine called a ribosome. Its job is to translate DNA sequences into proteins, the workhorse compounds that sustain you and all living things.

29 Jun 2013

Study: Pluripotent stem cell line-derived neurons survive and respond to cues in the primate brain

A team of researchers from Rush University, Yale University, the University of Colorado and the St. Kitts Biomedical Research Foundation transplanted human embryonic stem cells into primate laboratory animals modeled with Parkinson's disease and found "robust survival" of the cells after six weeks and indications that the cells were "well integrated" into the host animals.

29 Jun 2013

Olfactory ensheathing cells treatment improves neurological function in SCI patients: Study

A team of researchers in Poland who treated three of six paraplegics with spinal cord injury using transplanted olfactory ensheathing cells found that the three treated patients showed neurological improvement and no adverse effects while the three control patients who did not receive transplants saw no improvement.

29 Jun 2013

$Higher levels of Omega-3 fatty acids may reduce risk for hip fractures in postmenopausal women$

Higher levels of Omega-3 fatty acids may reduce risk for hip fractures in postmenopausal women

Higher levels of omega-3 fatty acids in the blood may reduce the risk for hip fractures in postmenopausal women, recent research suggests.

28 Jun 2013

New approaches to regenerate insulin-producing cells for type I diabetes

They have also shown that any pancreatic β cells can be regenerated several times and that chemically-induced diabetes in mice can thus be "treated" repeatedly. The challenge for the researchers is now to show that these procedures can be applied to humans.

28 Jun 2013

Chromosomal deletion associated with changes in brain's white matter and delays language acquisition

A chromosomal deletion is associated with changes in the brain's white matter and delayed language acquisition in youngsters from Southeast Asia or with ancestral connections to the region, said an international consortium led by researchers at Baylor College of Medicine.

28 Jun 2013

Research shows food contaminants are responsible for metabolic changes in obese mice

In order to get a better understanding of these effects, researchers from the Inserm cardiovascular, metabolism, diabetology and nutrition unit introduced a "cocktail" of contaminants mixed with low doses of dioxin, PCB, bisphenol A and phtalates into the feeding of mice that had already been rendered obese by a high-fat diet.

28 Jun 2013

Medical Science News

Researchers discover an important mechanism that regulates proteasome activity

Researchers find fear can increase or decrease ability to discriminate among sounds depending on context

Protein in liver plays a crucial role in mice's pregnancy and human menstrual cycle

Scientists identify neuronal circuits in spinal cord control limb alternation during walking

Research: Systemic dose of dendritic cells prevent rejection in kidney transplantation

Tiny RNA molecules work as powerful regulators of immune response in mammals

Study shows autophagy blockers play a role in treatment of non-small-cell lung cancer

Biomolecular interactions of nanoparticles can improve drug development, optical sensors and more

Synthetic biology technology could lead to new antibiotics, modified protein-generators

Study shows lymphatic circulatory system may be intimately involved in vascular disorders

Researchers develop new drug delivery systems to treat cancer by blocking signaling receptor

Ecology, evolution of infectious diseases to be highlighted at ESA's annual meeting

Low doses of arsenic and estrogen can cause cancer in prostate cells, study finds

Berkeley Lab scientists create atomic-scale structure of ribosome

Study: Pluripotent stem cell line-derived neurons survive and respond to cues in the primate brain

Olfactory ensheathing cells treatment improves neurological function in SCI patients: Study

Higher levels of Omega-3 fatty acids may reduce risk for hip fractures in postmenopausal women

New approaches to regenerate insulin-producing cells for type I diabetes

Chromosomal deletion associated with changes in brain's white matter and delays language acquisition

Research shows food contaminants are responsible for metabolic changes in obese mice

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

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