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Self-propelled microrockets using stomach acid as fuel may help perform microsurgery

An advance in micromotor technology akin to the invention of cars that fuel themselves from the pavement or air, rather than gasoline or batteries, is opening the door to broad new medical and industrial uses for these tiny devices, scientists said here today. Their update on development of the motors - so small that thousands would fit inside this "o" - was part of the 245th National Meeting & Exposition of the American Chemical Society, the world's largest scientific society, being held here this week.

11 Apr 2013

Androgen receptors found to be a potential target in breast cancer

Estrogen and progesterone receptors, and the gene HER2 - these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: androgen receptors.

11 Apr 2013

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

Omeros Corporation today announced positive data in the most commonly used model for studying the clinical and pathological features of multiple sclerosis (MS), further advancing its development program of GPR17-targeting compounds for the treatment of MS. Compounds previously discovered by Omeros that inhibit GPR17, an orphan G protein-coupled receptor (GPCR) unlocked by Omeros, significantly improved function from experimental autoimmune encephalomyelitis (EAE) in mice.

11 Apr 2013

Modulation of cerebral endocannabinoid system may help treat Fragile X chromosome syndrome

Researchers at the University of the Basque Country (UPV/EHU) and the Achucarro neurosciences centre have discovered a new therapy for the fragile X chromosome syndrome. This new therapy proposes the modulation of the cerebral endocannabinoid system in order to ameliorate the symptoms of the disease.

11 Apr 2013

Gold nano-bullets to defeat cancer

Cutting edge research into an experimental therapy that deploys nano-particles of gold in the fight against cancer earned an Alberta high school student, 16, top national honours today in the 2013 "Sanofi BioGENEius Challenge Canada" (SBCC).

11 Apr 2013

OncoMed highlights progress of anti-cancer biologics at AACR annual meeting

OncoMed Pharmaceuticals, Inc., a clinical-stage company developing novel therapeutics that target cancer stem cells (CSCs), or tumor-initiating cells, today summarized new data highlighting the progress of OncoMed's pipeline of anti-cancer biologics presented this week in an oral presentation and five posters at the Annual Meeting of the American Association of Cancer Research in Washington, DC.

11 Apr 2013

Virginia Tech scientists provide new evidence that biofilms are at work in survival of Salmonella

Virginia Tech scientists have provided new evidence that biofilms - bacteria that adhere to surfaces and build protective coatings - are at work in the survival of the human pathogen Salmonella.

11 Apr 2013

Study demonstrates successful use of fat cells to support prolonged growth of human hematopoietic stem cells

One of the main obstacles that stands in the way of using human hematopoietic stem cells (hHSCs) to treat a variety of diseases is the difficulty growing them in culture—they quickly die or differentiate into other cell types. A series of experiments that demonstrate the successful use of fat cells as part of a feeder layer to support prolonged growth of hHSCs in culture is reported in an article in BioResearch Open Access, a bimonthly peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers.

11 Apr 2013

New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

Deep inside your brain, a legion of stem cells lies ready to turn into new brain and nerve cells whenever and wherever you need them most. While they wait, they keep themselves in a state of perpetual readiness - poised to become any type of nerve cell you might need as your cells age or get damaged.

11 Apr 2013

Study shows genetic variant reduces pain severity associated with sexual assault

One in five U.S. women are sexually assaulted in their lifetimes and more than half experience severe pain during the week following an attack.

11 Apr 2013

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Scientists at The Scripps Research Institute have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how to prevent it.

11 Apr 2013

Cellectis CanCELL cell lines enable drug positioning in cancer pathways

CanCELL cell lines are featuring gene knock-outs of the major cancer relevant oncogenes and tumor suppressor genes. This new product line answers identified market needs in oncology research and drug discovery.

11 Apr 2013

Study reports role of cytochrome c oxidase as prognostic marker in GBM patients' tumor tissues

Researchers may have discovered a more accurate way to predict how long patients with the deadliest form of brain cancer will live, according to an analysis by researchers from the University of Alabama at Birmingham published today in the journal PLOS ONE.

11 Apr 2013

New data on use of PBD dimers as warheads in ADCs presented at AACR annual meeting

Spirogen, a leading oncology-focused company developing DNA sequence targeted agents, and BioAtla LLC, a San Diego headquartered antibody therapeutics developer, today announced new data on the use of pyrrolobenzodiazepine (PBD) dimers as warheads in antibody drug conjugates (ADCs) at the annual meeting of the American Association for Cancer Research (AACR) in Washington, DC.

11 Apr 2013

SAGIC researchers aim to compile genetic, genomic and phenotypic data of sleep apnea patients

As more and more data indicate that sleep apnea is linked with cardiovascular disease, stroke, diabetes and even an increase in deaths related to car accidents, an international consortium spanning five continents is working together to unravel the genetic basis for the condition.

11 Apr 2013

Brain works from subconscious mental categories it creates based on experiences

Your brain knows it's time to cook when the stove is on, and the food and pots are out. When you rush away to calm a crying child, though, cooking is over and it's time to be a parent. Your brain processes and responds to these occurrences as distinct, unrelated events.

11 Apr 2013

Reduction in neurogenesis associated with loss of certain cognitive faculties

These results incentivise the development of targeted therapies enabling improved neurone production to alleviate cognitive decline in the elderly and reduce the cerebral lesions caused by radiotherapy.

11 Apr 2013

New research suggests feeling powerful may protect against consequences of stereotype threat

New research from social psychologists at Indiana University Bloomington suggests that feeling powerful might protect against the debilitating effects of negative stereotypes.

11 Apr 2013

People who practice sport have better cognitive performance, researchers say

New scientific evidence seems to confirm the famous Roman saying "Mens sana in corpore sano". Researchers from the University of Granada have demonstrated that people who normally practice sport have a better cognitive performance than those with bad physical health.

11 Apr 2013

First-in-humans study introduces next generation cell therapy for heart failure patients

Translating a Mayo Clinic stem-cell discovery, an international team has demonstrated that therapy with cardiopoietic (cardiogenically-instructed) or "smart" stem cells can improve heart health for people suffering from heart failure.

11 Apr 2013

Medical Science News

Self-propelled microrockets using stomach acid as fuel may help perform microsurgery

Androgen receptors found to be a potential target in breast cancer

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

Modulation of cerebral endocannabinoid system may help treat Fragile X chromosome syndrome

Gold nano-bullets to defeat cancer

OncoMed highlights progress of anti-cancer biologics at AACR annual meeting

Virginia Tech scientists provide new evidence that biofilms are at work in survival of Salmonella

Study demonstrates successful use of fat cells to support prolonged growth of human hematopoietic stem cells

New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

Study shows genetic variant reduces pain severity associated with sexual assault

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Cellectis CanCELL cell lines enable drug positioning in cancer pathways

Study reports role of cytochrome c oxidase as prognostic marker in GBM patients' tumor tissues

New data on use of PBD dimers as warheads in ADCs presented at AACR annual meeting

SAGIC researchers aim to compile genetic, genomic and phenotypic data of sleep apnea patients

Brain works from subconscious mental categories it creates based on experiences

Reduction in neurogenesis associated with loss of certain cognitive faculties

New research suggests feeling powerful may protect against consequences of stereotype threat

People who practice sport have better cognitive performance, researchers say

First-in-humans study introduces next generation cell therapy for heart failure patients

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The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

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