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Research findings shed light on how neurons translate sensory input into actions

New research by scientists at the University of Massachusetts Medical School shows at the single cell level how an external stimulus sets off a molecular chain reaction in the transparent roundworm C. elegans, a process in which a single neurotransmitter coordinates and times two separate actions.

3 Apr 2013

PARP inhibitors can be novel treatment strategy for cisplatin-resistant cancer

Poly (ADP-ribose) polymerase inhibitors may be a novel treatment strategy for patients with cancer that has become resistant to the commonly used chemotherapy drug cisplatin, according to data from a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research.

3 Apr 2013

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute have discovered that an imbalance between an enzyme called neutrophil elastase and its inhibitor causes inflammation, obesity, insulin resistance, and fatty liver disease.

3 Apr 2013

Report shows identical genetic mutations are shared among neurodevelopmental disorders

A paper published this month in the prestigious medical journal The Lancet Neurology suggests that a broad spectrum of developmental and psychiatric disorders, ranging from autism and intellectual disability to schizophrenia, should be conceptualized as different manifestations of a common underlying denominator, "developmental brain dysfunction," rather than completely independent conditions with distinct causes.

3 Apr 2013

Salk neuroscientist applauds launch of BRAIN Initiative

Salk neuroscientist Terrence J. Sejnowski joined President Barack Obama in Washington, D.C., on April 2, 2013, at the launch of the Brain Research through Advancing Innovative Neurotechnologies Initiative-a major Administration neuroscience effort that advances and builds upon collaborative scientific work by leading brain researchers such as Salk's own Sejnowski.

3 Apr 2013

RUB biologists report that vitamin P ensures survival of motor neurons in culture

Biologists from the Ruhr-Universit-t Bochum have explored how to protect neurons that control movements from dying off.

3 Apr 2013

Doctors give new hope for leukemia patients

Leukemia patients receive a bone marrow transplant, which allows them to build a "new" immune system. However, this immune system not only attacks cancer cells but healthy tissue too.

3 Apr 2013

Antibodies neutralize mosquito-transmitted chikungunya virus, researchers reveal

Researchers have learned the precise structure of the mosquito-transmitted chikungunya virus pathogen while it is bound to antibodies, showing how the infection is likely neutralized.

3 Apr 2013

Obama to announce initiative to map human brain

The New York Times reports that President Barack Obama will unveil a broad new research initiative Tuesday, starting with $100 million next year, to find ways to record and map human brain circuits.

3 Apr 2013

Kavli Foundation applauds launch of new brain research initiative

The Kavli Foundation applauds today's launch by President Obama of his Administration's ambitious research effort to understand the brain by deciphering the brain's activity that gives rise to our perceptions, our experiences and our consciousness.

3 Apr 2013

Researchers find association between melatonin, type 2 diabetes

With previous evidence suggesting that melatonin may have a role in glucose metabolism, researchers have found an independent association between decreased secretion of melatonin and an increased risk for the development of type 2 diabetes, according to a study in the April 3 issue of JAMA.

3 Apr 2013

CU Cancer Center researchers identify switch that regulates production of E-Cadherin

Prostate cancer doesn't kill in the prostate - it's only once the disease travels to bone, lung, liver, etc. that it turns fatal. Previous studies have shown that loss of the protein E-Cadherin is essential for this metastasis.

3 Apr 2013

UC Davis scientists find mechanism in metabolized omega-3 fatty acid that helps combat cancer

A team of UC Davis scientists has found that a product resulting from a metabolized omega-3 fatty acid helps combat cancer by cutting off the supply of oxygen and nutrients that fuel tumor growth and spread of the disease.

3 Apr 2013

Study shows cholesterol rafts can shepherd genetic payloads into cancer cells

DNA, siRNA and miRNA can reprogram cancer cells - that is, if these nucleic acids could cross through the cell membrane. A University of Colorado Cancer Center study published today in the journal Therapeutic Delivery shows that cholesterol "rafts" can shepherd genetic payloads into cancer cells.

3 Apr 2013

Scientists use multi-analyte approach to determine exposure to tobacco constituents of snus users

Scientists at British American Tobacco have used a multi-analyte approach to determine the level of exposure to tobacco constituents of snus users. The results show that, generally, less than a third of each constituent measured was extracted by consumers during use.

2 Apr 2013

Scientists say DHA-rich fish oil enhances B cell activity

Fish oil rich in DHA and EPA is widely believed to help prevent disease by reducing inflammation, but until now, scientists were not entirely sure about its immune enhancing effects. A new report appearing in the April 2013 issue of the Journal of Leukocyte Biology, helps provide clarity on this by showing that DHA-rich fish oil enhances B cell activity, a white blood cell, challenging the notion that fish oil is only immunosuppressive.

2 Apr 2013

Researchers develop new guidelines to treat recently diagnosed multiple myeloma patients

Researchers at Mayo Clinic Cancer Center have developed new guidelines to treat recently diagnosed multiple myeloma patients who are not participating in clinical trials. The guidelines give physicians practical, easy to follow recommendations for providing initial therapy, stem cell transplant and maintenance therapy.

2 Apr 2013

Discovery of new signalling pathway creates hope for hormone therapy resistance

A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant.

2 Apr 2013

New born neurons as a therapeutic strategy: an interview with Mi-Hyeon Jang, Mayo Clinic in Rochester, Minnesota

There are two regions in the brain that continue to produce new neurons well into adulthood. One of these regions is the hippocampus and as we converse this region is actively involved in memory formation, mood regulation and cognition.

2 Apr 2013

ShopSmart magazine's April issue features answers to common questions about Vitamin D

Vitamin D has been touted as the answer to all kinds of health problems, but many of these claims are overblown. The April 2013 issue of ShopSmart magazine, from Consumer Reports, features answers to some of the most common questions about Vitamin D and names the best from its tests of 32 products.

2 Apr 2013

Medical Science News

Research findings shed light on how neurons translate sensory input into actions

PARP inhibitors can be novel treatment strategy for cisplatin-resistant cancer

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Report shows identical genetic mutations are shared among neurodevelopmental disorders

Salk neuroscientist applauds launch of BRAIN Initiative

RUB biologists report that vitamin P ensures survival of motor neurons in culture

Doctors give new hope for leukemia patients

Antibodies neutralize mosquito-transmitted chikungunya virus, researchers reveal

Obama to announce initiative to map human brain

Kavli Foundation applauds launch of new brain research initiative

Researchers find association between melatonin, type 2 diabetes

CU Cancer Center researchers identify switch that regulates production of E-Cadherin

UC Davis scientists find mechanism in metabolized omega-3 fatty acid that helps combat cancer

Study shows cholesterol rafts can shepherd genetic payloads into cancer cells

Scientists use multi-analyte approach to determine exposure to tobacco constituents of snus users

Scientists say DHA-rich fish oil enhances B cell activity

Researchers develop new guidelines to treat recently diagnosed multiple myeloma patients

Discovery of new signalling pathway creates hope for hormone therapy resistance

New born neurons as a therapeutic strategy: an interview with Mi-Hyeon Jang, Mayo Clinic in Rochester, Minnesota

ShopSmart magazine's April issue features answers to common questions about Vitamin D

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