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Study examines how bacteria clog medical devices

A new study has exam-ined how bac-te-ria clog med-ical devices, and the result isn't pretty. The microbes join to cre-ate slimy rib-bons that tan-gle and trap other pass-ing bac-te-ria, cre-at-ing a full block-age in a star-tlingly short period of time.

3 Mar 2013

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

The removal of a genetic roadblock could improve the efficiency of converting adult cells into stem cells by 10 to 30 times, report scientists from The Methodist Hospital Research Institute and two other institutions in the latest issue of Cell.

3 Mar 2013

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

In an article published as the cover story of the March 2013 issue of Nature Chemical Biology, Lindsey James, PhD, research assistant professor in the lab of Stephen Frye, Fred Eshelman Distinguished Professor in the UNC School of Pharmacy and member of the UNC Lineberger Comprehensive Cancer Center, announced the discovery of a chemical probe that can be used to investigate the L3MBTL3 methyl-lysine reader domain.

3 Mar 2013

Researchers identify mechanisms that connect variety of diseases linked with inflammation

A study led by researchers at Boston University School of Medicine (BUSM) has identified epigenetic mechanisms that connect a variety of diseases associated with inflammation.

3 Mar 2013

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders. University of Michigan researchers have discovered that inhibiting a signaling pathway in some of the transplanted cells could prevent the most serious potential complications of the procedure, a conflict between the transplanted cells and the recipient's own tissue called graft-versus-host disease.

2 Mar 2013

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune response unable to kill off the tumour's cancerous cells.

2 Mar 2013

Significant link between defective viruses and increased rate of transmission of major disease

Defective viruses, thought for decades to be essentially garbage unrelated to the transmission of normal viruses, now appear able to play an important role in the spread of disease, new research by UCLA life scientists indicates.

2 Mar 2013

Combination of two environmental factors contributes to schizophrenia

The interplay between an infection during pregnancy and stress in puberty plays a key role in the development of schizophrenia, as behaviourists from ETH Zurich demonstrate in a mouse model. However, there is no need to panic.

2 Mar 2013

Book shows how free will works in the brain

A new theory of brain function by Peter Ulric Tse, a professor of cognitive neuroscience at Dartmouth College, suggests that free will is real and has a biophysical basis in the microscopic workings of our brain cells.

2 Mar 2013

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.

2 Mar 2013

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression of the immune system, but these therapies can leave patients vulnerable to infection.

2 Mar 2013

Researchers can now predict fear memory formation

Psychologists at the University of Amsterdam (UvA) have discovered that changes in patterns of brain activity during fearful experiences predict whether a long-term fear memory is formed. The research results have recently been published in the prestigious scientific journal Nature Neuroscience.

2 Mar 2013

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain access to oxygen and nutrients, necessitating an expansion of the cardiac vasculature.

2 Mar 2013

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.

2 Mar 2013

Study shows triple-negative breast cancer cells missing key enzyme

A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain - providing insight into potential therapeutic targets to treat the aggressive cancer.

2 Mar 2013

Study links grape seed and skin extracts with high-fat-diet-induced renal disease

New insight into grape seed extract as a therapeutic and preventative measure to fight obesity-induced kidney damage is presented in a new study. Grape seed and skin extract (GSSE) is known to contain powerful antioxidants.

1 Mar 2013

RNA interference identifies function of genes linked with cardiovascular disease

Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease.

1 Mar 2013

Researchers elucidate how Fgf8 is controlled by multiple regulatory elements in mammal embryos

During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in this process, controlling in particular the growth of the limbs and the formation of the different regions of the brain. Researchers at EMBL have elucidated how Fgf8 in mammal embryos is, itself, controlled by a series of multiple, interdependent regulatory elements.

1 Mar 2013

Amoxicillin effectiveness: an interview with Prof Paul Little, University of Southampton

Amoxicillin is a broad spectrum penicillin, and in the UK is one of the most frequently used antibiotics. It is commonly used either on its own or, where there are particular concerns about resistance, in combination as Co-amoxiclav (as Amoxicillin-clavulanic acid) which extends its anti-bacterial spectrum.

1 Mar 2013

Structural connectome maps reveal new details about agenesis of the corpus callosum

Combining hospital MRIs with the mathematical tool known as network analysis, a group of researchers at UC San Francisco and UC Berkeley have mapped the three-dimensional global connections within the brains of seven adults who have genetic malformations that leave them without the corpus callosum, which connects the left and right sides of the brain.

1 Mar 2013

Medical Science News

Study examines how bacteria clog medical devices

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

Researchers identify mechanisms that connect variety of diseases linked with inflammation

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

Significant link between defective viruses and increased rate of transmission of major disease

Combination of two environmental factors contributes to schizophrenia

Book shows how free will works in the brain

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

Researchers can now predict fear memory formation

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

Study shows triple-negative breast cancer cells missing key enzyme

Study links grape seed and skin extracts with high-fat-diet-induced renal disease

RNA interference identifies function of genes linked with cardiovascular disease

Researchers elucidate how Fgf8 is controlled by multiple regulatory elements in mammal embryos

Amoxicillin effectiveness: an interview with Prof Paul Little, University of Southampton

Structural connectome maps reveal new details about agenesis of the corpus callosum

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

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