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Article provides examples of how epigenetic drug treatments could be beneficial in treating cancers

A review article by researchers at Boston University School of Medicine (BUSM) proposes a new epigenetic hypothesis linked to tumor production and novel ideas about what causes progenitor cells to develop into cancer cells. Published in the February 2013 issue of Epigenomics, the article provides examples of how epigenetic drug treatments could be beneficial in treating cancers while also decreasing the likelihood of cancer relapse.

21 Feb 2013

BCHE gene variant predicts extent of plaque deposits in Alzheimer's

A study combining genetic data with brain imaging, designed to identify genes associated with the amyloid plaque deposits found in Alzheimer's disease patients, has not only identified the APOE gene -- long associated with development of Alzheimer's -- but has uncovered an association with a second gene, called BCHE.

21 Feb 2013

UCSD molecular biologist to receive Breakthrough Prize in Life Sciences

Napoleone Ferrara, MD, PhD, the molecular biologist credited with helping decipher how tumors grow and now senior deputy director for basic sciences at the University of California, San Diego Moores Cancer Center, was today named one of 11 recipients of the inaugural Breakthrough Prize in Life Sciences, which comes with a $3 million cash award.

21 Feb 2013

Dietary antioxidants may not protect against stroke and dementia

Contrary to other research, a new study found that the total level of antioxidants in people's diets is not related to their risk of developing stroke or dementia.

21 Feb 2013

NINDS to award TSRI scientist with $3.5M Jacob K. Javits Neuroscience Investigator Award

Ron Davis, PhD, chair of the Neuroscience Department on the Florida campus of The Scripps Research Institute, has been selected to receive a prestigious $3.5 million Jacob K. Javits Neuroscience Investigator Award for his work on the complex biology of memory formation and the disorders that disrupt it.

21 Feb 2013

Osteopontin plays a role in X-linked hypophosphatemia

Diagnosed in toddlers, X-linked hypophosphatemia (XLH) is the most common form of heritable rickets, in which soft bones bend and deform, and tooth abscesses develop because infections penetrate soft teeth that are not properly calcified. Researchers at McGill University and the Federal University of Sao Paulo have identified that osteopontin, a major bone and tooth substrate protein, plays a role in XLH. Their discovery may pave the way to effectively treating this rare disease.

21 Feb 2013

New bio-mimicking therapeutics could help treat skin wounds

In "before" and "after" photos from advertisements for wound-healing ointments, bandages and antibiotic creams, we see an injury transformed from an inflamed red gash to smooth and flawless skin. What we don't appreciate is the vital role that our own natural biomolecules play in the healing process, including their contribution to the growth of new cells and the development of new blood vessels that provide nutrients to those cells.

21 Feb 2013

Signaling pathway might determine genetic susceptibility for fetal alcohol spectrum disorder

Fetal alcohol syndrome is the leading preventable cause of developmental disorders in developed countries. And fetal alcohol spectrum disorder (FASD), a range of alcohol-related birth defects that includes fetal alcohol syndrome, is thought to affect as many as 1 in 100 children born in the United States.

21 Feb 2013

GCP could help lengthen life expectancy of certain prostate cancer patients

A natural, nontoxic product called genistein-combined polysaccharide, or GCP, which is commercially available in health stores, could help lengthen the life expectancy of certain prostate cancer patients, UC Davis researchers have found.

21 Feb 2013

Two research studies to examine factors related to early development of breast cancer

The Cancer Institute of New Jersey and its System Partner Meridian Health are working together on two research studies to examine factors related to the early development of breast cancer.

21 Feb 2013

Researchers uncover neurological basis of speech motor control

A team of researchers at UC San Francisco has uncovered the neurological basis of speech motor control, the complex coordinated activity of tiny brain regions that controls our lips, jaw, tongue and larynx as we speak.

21 Feb 2013

Four genetic variations may increase risk of colorectal cancer

An international research team co-led by cancer prevention researcher Ulrike "Riki" Peters, Ph.D., M.P.H., and biostatistician Hsu Li, Ph.D., at Fred Hutchinson Cancer Research Center has identified variations in four genes that are linked to an increased risk of colorectal cancer.

21 Feb 2013

Methylene blue inactivates molecular residues that promote bonding of tau proteins

The study published in "Angewandte Chemie" might help to work out strategies for developing potential drugs. As the team of scientist including Markus Zweckstetter and Eckhard Mandelkow report, methylene blue inactivates molecular residues that promote the bonding of tau proteins.

21 Feb 2013

Sleep-deprived people select greater portion sizes of energy-dense snacks and meals

New research from Uppsala University shows that sleep-deprived people select greater portion sizes of energy-dense snacks and meals than they do after one night of normal sleep. Poor sleep habits can therefore affect people's risk of becoming overweight in the long run. The findings are published in Psychoneuroendocrinology.

20 Feb 2013

Heart OMics in AGEing project receives European Commission grant

The HOMAGE (Heart OMics in AGEing) project, coordinated by the French National Institute of Health and Medical Research (INSERM), has been awarded a grant by the European Commission for a 6 year period.

20 Feb 2013

Study demonstrates function of newly discovered regulatory mechanism of myeloid cells in cancer

Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer.

20 Feb 2013

Resistant starch kills pre-cancerous cells and reduces inflammation

As the name suggests, you can't digest resistant starch so it ends up in the bowel in pretty much the same form it entered your mouth. As unlovely as that seems, once in the bowel this resistant starch does some important things, including decreasing bowel pH and transit time, and increasing the production of short-chain fatty acids. These effects promote the growth of good bugs while keeping bad bugs at bay.

20 Feb 2013

Study determines frequency of genetic variants linked to alcoholism for Spanish population

Research done at the UPV/EHU-University of the Basque Country has determined the frequency of genetic variants linked to alcoholism for the Spanish population, and its incidence not only in individuals with a high level of alcohol intake, but also in individuals with alcohol dependence.

20 Feb 2013

Healthy adults with shorter telomere length more likely to develop upper respiratory infection

Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely to develop experimentally-induced upper respiratory infection than participants with longer telomeres, according to results of preliminary research published in the February 20 issue of JAMA.

20 Feb 2013

Liposomes not capable of transporting themselves deep into the skin

Liposomes are small fat capsules, often added to beauty products. According to the beauty industry liposomes are capable of transporting active ingredients deep into the skin and release the active ingredients so that they can alter the skin-s structure by rejuvenating and smoothing the skin.

20 Feb 2013

Medical Science News

Article provides examples of how epigenetic drug treatments could be beneficial in treating cancers

BCHE gene variant predicts extent of plaque deposits in Alzheimer's

UCSD molecular biologist to receive Breakthrough Prize in Life Sciences

Dietary antioxidants may not protect against stroke and dementia

NINDS to award TSRI scientist with $3.5M Jacob K. Javits Neuroscience Investigator Award

Osteopontin plays a role in X-linked hypophosphatemia

New bio-mimicking therapeutics could help treat skin wounds

Signaling pathway might determine genetic susceptibility for fetal alcohol spectrum disorder

GCP could help lengthen life expectancy of certain prostate cancer patients

Two research studies to examine factors related to early development of breast cancer

Researchers uncover neurological basis of speech motor control

Four genetic variations may increase risk of colorectal cancer

Methylene blue inactivates molecular residues that promote bonding of tau proteins

Sleep-deprived people select greater portion sizes of energy-dense snacks and meals

Heart OMics in AGEing project receives European Commission grant

Study demonstrates function of newly discovered regulatory mechanism of myeloid cells in cancer

Resistant starch kills pre-cancerous cells and reduces inflammation

Study determines frequency of genetic variants linked to alcoholism for Spanish population

Healthy adults with shorter telomere length more likely to develop upper respiratory infection

Liposomes not capable of transporting themselves deep into the skin

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