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University of Sheffield experts recreate randomly distributed stem cell sticky spots

Randomly distributed sticky spots which are integral to the development of stem cells by maximising adhesion and acting as internal scaffolding have been artificially recreated by experts from the University of Sheffield for the first time.

14 Dec 2012

Meridian completes beta trials for two new illumigene molecular amplification tests

Meridian Bioscience, Inc. today announced that it has successfully completed beta trials for two new illumigene molecular amplification tests.

14 Dec 2012

MicroRNA-218 especially low in medulloblastoma

Between the blueprint of the genome and the products of its expression lie microRNAs, which can boost or lower the rate at which genes become stuff. In fact, many cancers use microRNA to magnify the expression of faulty genes or shrink the expression of helpful genes that would otherwise suppress tumors. A University of Colorado Cancer Center study published in the December issue of the Journal of Biological Chemistry shows that in medulloblastoma, a malignant brain tumor of children, microRNA-218 is especially low.

14 Dec 2012

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Scientists have identified a new mutation in the gene that causes the inherited disease known as Alpha-1 Antitrypsin Deficiency (Alpha-1), which affects roughly one in 2,500 people of European descent.

14 Dec 2012

Computer simulation can predict risk of irregular heart rhythms and sudden cardiac death

A computer model of the heart wall predicted risk of irregular heart rhythms and sudden cardiac death in patients, paving the way for the use of more complex cardiac models to calculate the consequences of genetic, lifestyle and other changes to the heart.

14 Dec 2012

Researchers discover two-faced group of cells at work in human colon cancer

Northwestern Medicine researchers have discovered a "two-faced" group of cells at work in human colon cancer, with opposing functions that can suppress or promote tumor growth. These cells are a subset of T-regulatory (Treg) cells, known to suppress immune responses in healthy individuals.

14 Dec 2012

Scientists discover FAIM molecule as potential biomarker for bone marrow cancer

Singapore scientists have identified FAIM, a molecule that typically prevents cell death, as a potential biomarker to identify an incurable form of cancer in the bone marrow.

14 Dec 2012

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They say the finding could lead to a new treatment for prostate cancers that are no longer controlled by hormone-blocking drugs.

14 Dec 2012

Arginase, IDO could hold clues to help 79 million Americans with prediabetes

Two enzymes that are elevated in prediabetes could hold clues to helping the 79 million Americans with the condition avoid serious vascular complications and maybe even identify those most at risk for full-blown diabetes, researchers say.

13 Dec 2012

UCL scientists discover more than 200 gene locations for Crohn's disease

More than two hundred gene locations have now been identified for the chronic bowel condition Crohn's Disease, in a study that analysed the entire human genome.

13 Dec 2012

Scientists isolate cancer stem cells that lead to growth of Wilms' tumours

Scientists have isolated cancer stem cells that lead to the growth of Wilms' tumours, a type of cancer typically found in the kidneys of young children. The researchers have used these cancer stem cells to test a new therapeutic approach that one day might be used to treat some of the more aggressive types of this disease.

13 Dec 2012

LED light instantly triggers or reverses depression-like behavior in rodents

A specific pattern of neuronal firing in a brain reward circuit instantly rendered mice vulnerable to depression-like behavior induced by acute severe stress, a study supported by the National Institutes of Health has found. When researchers used a high-tech method to mimic the pattern, previously resilient mice instantly succumbed to a depression-like syndrome of social withdrawal and reduced pleasure-seeking - they avoided other animals and lost their sweet tooth.

13 Dec 2012

Physical activity improves brain function in older generations

The physical benefits of regular exercise and remaining physically active, especially as we age, are well documented. However, it appears that it is not only the body which benefits from exercise, but the mind too. The evidence for this is published in a new review by Hayley Guiney and Liana Machado from the University of Otago, New Zealand, which focuses on the importance of physical activity in keeping and potentially improving cognitive function throughout life.

13 Dec 2012

China SFDA approves Veridex’s CellSearch test for women with metastatic breast cancer

Veridex, LLC today announced approval from the China State Food & Drug Administration (SFDA) for the CellSearch circulating tumor cell (CTC) test as an in vitro diagnostic for women with metastatic breast cancer.

13 Dec 2012

TU Darmstadt’s biosensor can diagnose African sleeping sickness before it breaks out

African sleeping sickness is an infectious disease that is widespread south of the Sahara Desert. Although the around sixty million people residing in tropical Africa run the risk of becoming infected with the disease every day, only around four million of them are monitored for the disease by disease-control authorities.

13 Dec 2012

New ESF strategic report identifies opportunities for research on human brain

A new strategic report, The Human Brain - From Cells to Society, Toward Better Mental Health in Europe, has been published today by the European Science Foundation (ESF). In a Europe where an estimated 38% of the population is affected by a disorder of the brain, it is becoming increasingly important to bring greater support to research in all areas of neuroscience.

13 Dec 2012

Scientists identify new antibiotic substances in Russian Brown frog's skin

Following up on an ancient Russian way of keeping milk from going sour - by putting a frog in the bucket of milk - scientists have identified a wealth of new antibiotic substances in the skin of the Russian Brown frog. The study appears in ACS' Journal of Proteome Research.

13 Dec 2012

Opioids already in the body can enhance malignant tendencies of human cancer cells

A study led by University of Chicago researcher Patrick A. Singleton, Ph.D. and published in the journal Anesthesiology has shown that, even without the addition of further opioids such as morphine, opioids already in the body can enhance the malignant tendencies of human cancer cells.

13 Dec 2012

Change of fatty diet can cause feelings like drug withdrawal and depression

Even before obesity occurs, eating fatty and sugary foods causes chemical changes in the brain, meaning that going on a diet might feel similar to going through drug withdrawal, according to a study published today by Dr. Stephanie Fulton of the University of Montreal's Faculty of Medicine and its affiliated CRCHUM Hospital Research Centre.

13 Dec 2012

Targeted micro-bubbles could help detect heart disease

Heart disease is a leading cause of death throughout the world. Doctors say that it is important to detect heart disease early before it becomes too serious. Now, researchers at the University of Missouri have found a way that they believe could help detect heart disease before it progresses too far as well as identify patients who are at risk for strokes.

13 Dec 2012

Medical Science News

University of Sheffield experts recreate randomly distributed stem cell sticky spots

Meridian completes beta trials for two new illumigene molecular amplification tests

MicroRNA-218 especially low in medulloblastoma

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Computer simulation can predict risk of irregular heart rhythms and sudden cardiac death

Researchers discover two-faced group of cells at work in human colon cancer

Scientists discover FAIM molecule as potential biomarker for bone marrow cancer

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Arginase, IDO could hold clues to help 79 million Americans with prediabetes

UCL scientists discover more than 200 gene locations for Crohn's disease

Scientists isolate cancer stem cells that lead to growth of Wilms' tumours

LED light instantly triggers or reverses depression-like behavior in rodents

Physical activity improves brain function in older generations

China SFDA approves Veridex’s CellSearch test for women with metastatic breast cancer

TU Darmstadt’s biosensor can diagnose African sleeping sickness before it breaks out

New ESF strategic report identifies opportunities for research on human brain

Scientists identify new antibiotic substances in Russian Brown frog's skin

Opioids already in the body can enhance malignant tendencies of human cancer cells

Change of fatty diet can cause feelings like drug withdrawal and depression

Targeted micro-bubbles could help detect heart disease

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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