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Researchers investigate GPER receptor as possible new drug target for breast cancer

Five-year breast cancer survival rates have improved dramatically over the past 50 years, but tumors can recur up to ten or more years after they are detected. When tumors recur, they are even more difficult to treat.

5 Dec 2012

Natural killer cell response detrimental to glioblastoma virotherapy

For the first time, researchers have demonstrated that the response of natural killer (NK) cells is detrimental to glioblastoma virotherapy, a novel way of treating malignant brain cancer by injecting a virus into the tumor.

5 Dec 2012

Combination of ketogenic diet and radiation therapy effectively treats malignant gliomas

A team of brain cancer researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has effectively treated brain tumor cells using a unique combination of diet and radiation therapy.

5 Dec 2012

Combining 5-fluorouracil and IL-1 beta inhibitor can improve effectiveness of chemotherapy

These results reveal how the immune system can then limit the effectiveness of some cancer chemotherapies. The researchers now intend to block the molecules responsible for negative immune system activation to increase the efficiency of chemotherapy. A clinical trial to test this hypothesis should begin very soon.

5 Dec 2012

Bioinformaticians use molecular simulations to explain specific step in HIV virion maturation

Bioinformaticians at IMIM (Hospital del Mar Medical Research Institute) and UPF (Pompeu Fabra University) have used molecular simulation techniques to explain a specific step in the maturation of the HIV virions, i.e., how newly formed inert virus particles become infectious, which is essential in understanding how the virus replicates.

5 Dec 2012

Dietary fish oil supplements could help heal bedsores

Chock-full of Omega-3 fatty acids and antioxidants, fish oil can help lower blood pressure, reduce inflammation in the skin and joints, and promote healthy fetal development. Now a Tel Aviv University researcher has found that it has a positive effect on bedsores, too.

5 Dec 2012

UC Berkeley professor wins Young Investigator Award by STEM CELLS journal

Dr Sanjay Kumar, MD, PhD has been named the winner of the Young Investigator Award by the journal STEM CELLS for leading research into the microenvironmental regulation of neural stem cells. The $10,000 prize is awarded annually to a young scientist whose paper has been judged to be of worldwide significance by a global jury.

5 Dec 2012

Mainz University neuroscientist professor receives ERC Advanced Grant

The European Research Council (ERC) has earmarked some EUR 2.5 million to fund research being conducted by neuroscientist Professor Dr. Robert Nitsch at the Mainz University Medical Center.

5 Dec 2012

New clues about B. burgdorferi could lead to novel strategy to reduce Lyme disease

New clues about the bacteria that cause Lyme disease could lead to a novel strategy to reduce infections, according to a study to be published in mBio-, the online open-access journal of the American Society for Microbiology, on December 4.

4 Dec 2012

Data from OncoSec Medical clinical studies to be presented at DNA Vaccines 2012 Conference

OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy and NeoPulse therapy to treat solid tumor cancers, announced it will be presenting at the DNA Vaccines 2012 Conference at the Loews Coronado Bay Resort in San Diego, California. OncoSec is a Silver Sponsor of the conference.

4 Dec 2012

Hebrew University researchers pave way for development of new approaches to cure malaria

More than a million people die each year of malaria caused by different strains of the Plasmodium parasite transmitted by the Anopheles mosquito. The medical world has yet to find an effective vaccine against the deadly parasite, which mainly affects pregnant women and children under the age of five. By figuring out how the most dangerous strain evades the watchful eye of the immune system, researchers from the Hebrew University of Jerusalem have now paved the way for the development of new approaches to cure this acute infection.

4 Dec 2012

Linagliptin may reduce brain damage following stroke in type 2 diabetic patients

In a study in mice, scientists at Karolinska Institutet in Sweden have discovered a new potential therapy that may reduce brain damage following stroke in type 2 diabetic patients. The suggested drug is already approved for the treatment of type 2 diabetes. However, the scientists hope that this new results, presented in the scientific journal Diabetes, also opens up the possibility to decrease brain injury after stroke in other patient groups with a high stroke risk.

4 Dec 2012

psi-GSH prevents neurodegeneration associated with Alzheimer's in mouse model

Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.

4 Dec 2012

New research finds bisphenol A in fetal liver tissues

New research from the University of Michigan School of Public Health found BPA, or bisphenol A, in fetal liver tissue, demonstrating that there is considerable exposure to the chemical during pregnancy.

4 Dec 2012

Researchers derive dopaminergic neurons from bone marrow stem cells in monkeys

Parkinson's disease is a degenerative disorder of the central nervous system that is characterized by tremors, rigidity, slowness of movement, and difficulty walking. It is caused by loss of the neurons that produce the neurotransmitter dopamine (known as dopaminergic neurons). One of the primary goals in Parkinson's disease research is to develop a replacement for dopaminergic neurons.

4 Dec 2012

New antibodies effective at preventing formation of toxic protein particles linked to Parkinson’s, AD

Antibodies developed by researchers at Rensselaer Polytechnic Institute are unusually effective at preventing the formation of toxic protein particles linked to Alzheimer's disease and Parkinson's disease, as well as Type 2 diabetes, according to a new study.

4 Dec 2012

Researchers describe role of calcium in ability of Yersinias to cause disease

A more than 50-year-old question has now been answered. Chemists and microbiologists at the Biological Chemistry Center at Umeå University in Sweden are now able to describe in detail the role of calcium in the ability of the plague bacterium Yersinias to cause disease.

4 Dec 2012

UI researchers develop neonatal piglet model to study micronutrient deficiencies

University of Illinois researchers have developed a model that uses neonatal piglets for studying infant brain development and its effect on learning and memory. To determine if the model is nutrient-sensitive, they have done some research on the effects of iron-deficient diets.

4 Dec 2012

Feeding probiotics to baby zebrafish accelerates their development into adulthood

Probiotics like those found in yogurt are not only good for people--they are also good for fish. A new study by scientists at the Institute of Marine and Environmental Technology found that feeding probiotics to baby zebrafish accelerated their development and increased their chances of survival into adulthood.

4 Dec 2012

Link between stress and brain activation in patients with seizure

A study reported here at the 66th American Epilepsy Society Annual Meeting has identified a significant difference in the brain response to stress in patients who believe stress is an important factor in their seizure control compared to patients who do not hold this belief.

4 Dec 2012

Medical Science News

Researchers investigate GPER receptor as possible new drug target for breast cancer

Natural killer cell response detrimental to glioblastoma virotherapy

Combination of ketogenic diet and radiation therapy effectively treats malignant gliomas

Combining 5-fluorouracil and IL-1 beta inhibitor can improve effectiveness of chemotherapy

Bioinformaticians use molecular simulations to explain specific step in HIV virion maturation

Dietary fish oil supplements could help heal bedsores

UC Berkeley professor wins Young Investigator Award by STEM CELLS journal

Mainz University neuroscientist professor receives ERC Advanced Grant

New clues about B. burgdorferi could lead to novel strategy to reduce Lyme disease

Data from OncoSec Medical clinical studies to be presented at DNA Vaccines 2012 Conference

Hebrew University researchers pave way for development of new approaches to cure malaria

Linagliptin may reduce brain damage following stroke in type 2 diabetic patients

psi-GSH prevents neurodegeneration associated with Alzheimer's in mouse model

New research finds bisphenol A in fetal liver tissues

Researchers derive dopaminergic neurons from bone marrow stem cells in monkeys

New antibodies effective at preventing formation of toxic protein particles linked to Parkinson’s, AD

Researchers describe role of calcium in ability of Yersinias to cause disease

UI researchers develop neonatal piglet model to study micronutrient deficiencies

Feeding probiotics to baby zebrafish accelerates their development into adulthood

Link between stress and brain activation in patients with seizure

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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