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Maternal cigarette smoking reduces reading accuracy in children

Yale School of Medicine researchers have found that children born to mothers who smoked more than one pack per day during pregnancy struggled on tests designed to measure how accurately a child reads aloud and comprehends what they read.

20 Nov 2012

Aradigm’s Lipoquin provides full protection in murine models of pneumonic plague

Scientists from the UK Defence Science and Technology Laboratory (Dstl) report, in a preliminary study, that they have demonstrated that a single dose of Aradigm Corporation's liposomal ciprofloxacin formulation Lipoquin administered 24 hours after exposure to a lethal dose of the bacterium Yersinia pestis provided full protection in a murine model of pneumonic plague.

20 Nov 2012

Scientists identify two genetic risk factors for sagittal craniosynostosis

Seattle Children's Research Institute, together with an international team of scientists and clinicians from 22 other institutions, have identified two genetic risk factors for the most common form of non-syndromic craniosynostosis, a birth defect in which the bony plates of an infant's skull prematurely fuse. The condition is known as sagittal craniosynostosis and often results in an abnormal head shape and facial features.

20 Nov 2012

IL-13 receptor system could play a major role in Parkinson's

Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed a key factor controlling damage to brain cells in a mouse model of Parkinson's disease.

20 Nov 2012

Researchers discover new cause of hydrocephalus

Researchers at the University of Iowa have discovered a new cause of hydrocephalus, a devastating neurological disorder that affects between one and three of every 1,000 babies born. Working in mice, the researchers identified a cell signaling defect, which disrupts immature brain cells involved in normal brain development.

20 Nov 2012

Researchers discover new gene for susceptibility to Alzheimer's disease

A large-scale international study involving French researchers from the Inserm-Institut Pasteur Lille-Universit- Lille Nord de France "Public health and molecular epidemiology of ageing-related diseases" joint research unit led by Philippe Amouyel, has just discovered a gene for susceptibility to a rare disease that causes susceptibility to a common one, Alzheimer's disease, providing evidence of the heterogeneous aetiology of Alzheimer's disease.

20 Nov 2012

KLF4 genetic factor prevents blood vessels from blockages

Researchers at Case Western Reserve University School of Medicine have identified a genetic factor that prevents blockages from forming in blood vessels, a discovery that could lead to new therapies for cardiovascular diseases.

20 Nov 2012

Boston and Cincinnati Children's Hospital to learn more about how autism develops

A network of five leading medical centers, led by Cincinnati Children's Hospital Medical Center and Boston Children's Hospital, has received a five-year, $12.5 million National Institutes of Health (NIH) grant to learn more about how autism develops.

20 Nov 2012

CFFT announces major expansion of research collaboration with Pfizer

Cystic Fibrosis Foundation Therapeutics Inc. (CFFT), the nonprofit drug discovery and development affiliate of the Cystic Fibrosis Foundation, today announced a major expansion of its research collaboration with Pfizer Inc. designed to discover new drugs to treat people with the most common mutation of CF, Delta F508.

20 Nov 2012

New fiber-optic device can deliver light to the brain in 3D

A new tool for neuroscientists delivers a thousand pinpricks of light to a chunk of gray matter smaller than a sugar cube. The new fiber-optic device, created by biologists and engineers at the Massachusetts Institute of Technology (MIT) in Cambridge, is the first tool that can deliver precise points of light to a 3-D section of living brain tissue. The work is a step forward for a relatively new but promising technique that uses gene therapy to turn individual brain cells on and off with light.

19 Nov 2012

Overexpression of BCL6 results in transformation of neural stem cells into cortical neurons

The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases.

19 Nov 2012

Four New York students named National Finalists in Siemens Competition

Months of dedication and hard work in science, technology, engineering and mathematics (STEM) paid off tonight for four students named National Finalists in the Siemens Competition in Math, Science & Technology, the nation's premier research competition.

19 Nov 2012

ReFIT algorithm improves speed and accuracy of neural prosthetics

When a paralyzed person imagines moving a limb, cells in the part of the brain that controls movement still activate as if trying to make the immobile limb work again. Despite neurological injury or disease that has severed the pathway between brain and muscle, the region where the signals originate remains intact and functional.

19 Nov 2012

New nanoparticle halts relapsing remitting multiple sclerosis in mouse model

In a breakthrough for nanotechnology and multiple sclerosis, a biodegradable nanoparticle turns out to be the perfect vehicle to stealthily deliver an antigen that tricks the immune system into stopping its attack on myelin and halt a model of relapsing remitting multiple sclerosis (MS) in mice, according to new Northwestern Medicine research.

19 Nov 2012

Induced-pluripotent stem cells not as genetically unstable as previously thought

Stanford University School of Medicine scientists have demonstrated, in a study conducted jointly with researchers at Yale University, that induced-pluripotent stem cells - the embryonic-stem-cell lookalikes whose discovery a few years ago won this year's Nobel Prize in medicine - are not as genetically unstable as was thought.

19 Nov 2012

NIH-funded scientists develop new treatment to combat autoimmune disorders in mouse model

In a mouse model of multiple sclerosis (MS), researchers funded by the National Institutes of Health have developed innovative technology to selectively inhibit the part of the immune system responsible for attacking myelin-the insulating material that encases nerve fibers and facilitates electrical communication between brain cells.

18 Nov 2012

Two genetic factors strongly associated with non-syndromic sagittal craniosynostosis

An international team of geneticists, pediatricians, surgeons and epidemiologists from 23 institutions across three continents has identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis ― premature closure of the bony plates of the skull.

18 Nov 2012

United States Pharmacopeial Convention to host Fifth Bioassay Workshop in Rockville

As a growing number of biologic drugs are treatments of choice for an expanding list of autoimmune disorders, inflammatory diseases, and certain cancers, bioassays play a critical role in establishing the functional integrity and potency of these products.

17 Nov 2012

Personality traits linked with individual's susceptibility to placebo effect from pain medicines

Personality traits might do more than help you win a popularity contest. According to new University of Michigan-led neuroscience research, co-authored by University of Maryland (UM) School of Dentistry Dean Christian S. Stohler, DMD, DrMedDent, such traits also might make you more likely to get pain relief from a placebo - a fake medicine.

17 Nov 2012

New way to stimulate transplanted human stem cell-derived neurons into a rodent hippocampus

Researchers and patients look forward to the day when stem cells might be used to replace dying brain cells in Alzheimer's disease and other neurodegenerative conditions. Scientists are currently able to make neurons and other brain cells from stem cells, but getting these neurons to properly function when transplanted to the host has proven to be more difficult.

17 Nov 2012

Medical Science News

Maternal cigarette smoking reduces reading accuracy in children

Aradigm’s Lipoquin provides full protection in murine models of pneumonic plague

Scientists identify two genetic risk factors for sagittal craniosynostosis

IL-13 receptor system could play a major role in Parkinson's

Researchers discover new cause of hydrocephalus

Researchers discover new gene for susceptibility to Alzheimer's disease

KLF4 genetic factor prevents blood vessels from blockages

Boston and Cincinnati Children's Hospital to learn more about how autism develops

CFFT announces major expansion of research collaboration with Pfizer

New fiber-optic device can deliver light to the brain in 3D

Overexpression of BCL6 results in transformation of neural stem cells into cortical neurons

Four New York students named National Finalists in Siemens Competition

ReFIT algorithm improves speed and accuracy of neural prosthetics

New nanoparticle halts relapsing remitting multiple sclerosis in mouse model

Induced-pluripotent stem cells not as genetically unstable as previously thought

NIH-funded scientists develop new treatment to combat autoimmune disorders in mouse model

Two genetic factors strongly associated with non-syndromic sagittal craniosynostosis

United States Pharmacopeial Convention to host Fifth Bioassay Workshop in Rockville

Personality traits linked with individual's susceptibility to placebo effect from pain medicines

New way to stimulate transplanted human stem cell-derived neurons into a rodent hippocampus

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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