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Complix to accelerate development of CPABs against intracellular disease targets

Complix announces that it has been awarded a €1.9 million grant (approximately USD$2.4 million) from the Flanders government through IWT (Agency for Innovation by Science and Technology in Flanders).

30 Oct 2012

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow nerve damage in patients with neurodegenerative diseases.

30 Oct 2012

Study identifies new prognostic biomarker and therapeutic target for adult B-ALL

New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target.

30 Oct 2012

IPSCs may be a viable source of patient-specific articular cartilage tissue

A team of Duke Medicine researchers has engineered cartilage from induced pluripotent stem cells that were successfully grown and sorted for use in tissue repair and studies into cartilage injury and osteoarthritis.

30 Oct 2012

IVF process negatively impacts women’s sexual relationships

An Indiana University study has found that women undergoing in-vitro fertilization report that the process of infertility treatment has many negative impacts on their sexual relationship with their partner. Little attention has been given to the sexual dynamics of couples as they navigate infertility and treatments such as IVF, despite the important role that sex plays in a couple's attempt to conceive a child.

30 Oct 2012

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

30 Oct 2012

Four transcription factor genes control processes related to heart and head muscle formation

A group of researchers in Israel, the United States and other nations have made important advances in the rapidly-expanding field of "regenerative medicine," outlining for the first time connections in genetic regulation that normally prevent birth defects in heart and facial muscles.

30 Oct 2012

Variation in size of red cell distribution width is linked with socioeconomic factors

It is well known that socioeconomic factors such as poverty and low education play a role in health, but new research released today at the American Public Health Association's 140th Annual Meeting in San Francisco, Calif., shows this association is also seen in biomarkers of the blood.

30 Oct 2012

C allele of rs1329650 may increase risk of both ADHD and smoking

A variation of a particular gene may link the behaviours typical of childhood attention hyperactivity disorder, or ADHD for short, and those associated with smoking, suggests research published online in the Archives of Disease in Childhood.

30 Oct 2012

Oxidative stress occurs in genetic models of alpha-1-antitrypsin deficiency

A team of researchers under the direction of Dr. Jeffrey Teckman in the Department of Pediatrics at St. Louis University, have demonstrated that oxidative stress occurs in a genetic model of alpha-1-antitrypsin deficiency.

30 Oct 2012

Nicotine exposure causes asthma in smoker's grandchildren

The dangers of smoking on smokers and their children are widely known but new research published in BioMed Central's open access journal BMC Medicine demonstrates that nicotine exposure also causes asthma in the smoker's grandchildren.

30 Oct 2012

Scientists discover β2-syntrophin protein as new prognosis marker for prostate cancer

Scientists have discovered a molecular 'tell' in laboratory experiments that could help doctors determine the severity of a patient's prostate cancer.

30 Oct 2012

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key "software" instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL's "software" is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets.

29 Oct 2012

Botanical treatment holds hope for triple-negative breast cancer

A unique formula made from medicinal mushrooms, traditional Chinese herbs and other natural ingredients inhibits aggressive, human triple-negative breast cancer and breast-to-lung metastasis in mice. This is the third peer-reviewed study to demonstrate the botanical formula's anticancer effects.

29 Oct 2012

Nano-reinforced plastics improve friction resistance of orthodontics

Brackets made from clear plastic polymer used in dental correction orthodontics have produced very good results in recent years, especially in relation to the improved esthetics when compared to metal brackets, but they do present certain problems of wear and tear within the mouth.

29 Oct 2012

Cellectis announces successful programming of immune system cells to kill cancer cells

Cellectis, the genome engineering specialist, has announced successfully programming cells from the immune system (T cells) to kill cancer cells. This technological breakthrough was revealed for the first time ever on Saturday, October 27th at the congress of the ESGCT (European Society of Gene & Cell Therapy) in Versailles, outside Paris.

29 Oct 2012

Researchers zero in on process by which stem cells maintain proper undifferentiated state

The ability of embryonic stem cells to differentiate into different types of cells with different functions is regulated and maintained by a complex series of chemical interactions, which are not well understood. Learning more about this process could prove useful for stem cell-based therapies down the road. New research from a team led by Carnegie's Yixian Zheng zeroes in on the process by which stem cells maintain their proper undifferentiated state.

29 Oct 2012

Improvements in rare cell isolation and common blood tests

At the Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS) to be held Oct. 28-Nov. 1, in Okinawa, Japan, University of Cincinnati researchers will present four papers, including one detailing improvements in rare cell isolation and one detailing improvements, in terms of cost and time, of common blood tests.

29 Oct 2012

Light-sensitive protein to study Parkinson's disease

Introducing a light-sensitive protein in transgenic nerve cells... transplanting nerve cells into the brains of laboratory animals... inserting an optic fibre in the brain and using it to light up the nerve cells and stimulate them into releasing more dopamine to combat Parkinson's disease...

29 Oct 2012

Precision receives U.S. patent allowance for DNE technology

Precision BioSciences, Inc., a leader in the field of genome engineering, today announced that the United States Patent and Trademark Office has issued a Notice of Allowance for U.S. Patent Application 13/457,041.

29 Oct 2012

Medical Science News

Complix to accelerate development of CPABs against intracellular disease targets

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

Study identifies new prognostic biomarker and therapeutic target for adult B-ALL

IPSCs may be a viable source of patient-specific articular cartilage tissue

IVF process negatively impacts women’s sexual relationships

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

Four transcription factor genes control processes related to heart and head muscle formation

Variation in size of red cell distribution width is linked with socioeconomic factors

C allele of rs1329650 may increase risk of both ADHD and smoking

Oxidative stress occurs in genetic models of alpha-1-antitrypsin deficiency

Nicotine exposure causes asthma in smoker's grandchildren

Scientists discover β2-syntrophin protein as new prognosis marker for prostate cancer

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

Botanical treatment holds hope for triple-negative breast cancer

Nano-reinforced plastics improve friction resistance of orthodontics

Cellectis announces successful programming of immune system cells to kill cancer cells

Researchers zero in on process by which stem cells maintain proper undifferentiated state

Improvements in rare cell isolation and common blood tests

Light-sensitive protein to study Parkinson's disease

Precision receives U.S. patent allowance for DNE technology

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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