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Study provides direct evidence for persistent activity in medial entorhinal cortex layer neurons

UCLA researchers have for the first time measured the activity of a brain region known to be involved in learning, memory and Alzheimer's disease during sleep. They discovered that this part of the brain behaves as if it's remembering something, even under anesthesia, a finding that counters conventional theories about memory consolidation during sleep.

8 Oct 2012

Researchers discover smallest and fastest-known RNA switches

A University of Michigan biophysical chemist and his colleagues have discovered the smallest and fastest-known molecular switches made of RNA, the chemical cousin of DNA. The researchers say these rare, fleeting structures are prime targets for the development of new antiviral and antibiotic drugs.

8 Oct 2012

NFKB1 gene variant may reduce risk of lung cancer

A variant in a gene involved with inflammation and the immune response is linked with a decreased risk of lung cancer. That is the finding of an analysis published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The results add to the growing body of literature implicating these processes in the development of lung cancer.

8 Oct 2012

Researchers discover 8 new loci associated with susceptibility to atopic dermatitis

Researchers at the RIKEN Center for Genomic Medicine (CGM) and their colleagues have identified 8 new loci associated with susceptibility to atopic dermatitis in the Japanese population.

8 Oct 2012

Researchers decipher how AP-1 gene regulator controls survival of liver tumor-initiating cells

Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible gene regulator, AP-1, controls the survival of liver tumor-initiating cells. These results, published in the online edition of Nature Cell Biology, could provide new preventive strategies and identify potentially targetable molecules to prevent liver cancer.

8 Oct 2012

Progenra’s USP7 and USP47 exert non-overlapping anticancer cell effects

Researchers at Progenra, Inc. announce the advanced online publication of the article "Selective Dual Inhibitors of the Cancer-related Deubiquitylating Proteases USP7 and USP47." The new article presents evidence of a therapeutic benefit resulting from dual inhibition of USP7 and a related enzyme, USP47.

8 Oct 2012

New insight into basis of opiate addiction

Chronic morphine exposure has the opposite effect on the brain compared to cocaine in mice, providing new insight into the basis of opiate addiction, according to Mount Sinai School of Medicine researchers.

8 Oct 2012

CytoDyn announces update on feline immunodeficiency virus therapeutic antibody program

CytoDyn Inc., a biotechnology company focused on the development of new therapies for combating infection with immune deficiency viruses, announced today that it is presenting an update on its Feline Immunodeficiency Virus (FIV) therapeutic antibody program at the 19th West Coast Retrovirus meeting in Palm Springs, California.

8 Oct 2012

FDA clears Fenwal's new plasma products

Fenwal Inc., a global leader specializing in separation technologies for blood and cell collection and therapy, announced today it has received clearance from the U.S. Food and Drug Administration for two new indications for collection of plasma products on the Fenwal Alyx and Amicus systems.

8 Oct 2012

New ways of how biological clock's neurons use electrical activity to keep behavioral rhythms in order

Biologists from New York University have uncovered new ways our biological clock's neurons use electrical activity to help keep behavioral rhythms in order. The findings, which appear in the journal Current Biology, also point to fresh directions for exploring sleep disorders and related afflictions.

6 Oct 2012

Researchers perfect map of vision in the brain based upon brain structure

Nearly 100 years after a British neurologist first mapped the blind spots caused by missile wounds to the brains of soldiers, Perelman School of Medicine researchers at the University of Pennsylvania have perfected his map using modern-day technology. Their results create a map of vision in the brain based upon an individual's brain structure, even for people who cannot see.

6 Oct 2012

Researchers identify mechanism that protects from developing uncontrollable fear

Researchers from the University of Exeter Medical School have for the first time identified the mechanism that protects us from developing uncontrollable fear.

6 Oct 2012

New light into evolution of human physiology and brain development

A skull fragment unearthed by anthropologists in Tanzania shows that our ancient ancestors were eating meat at least 1.5 million years ago, shedding new light into the evolution of human physiology and brain development.

6 Oct 2012

Social factors influence perceptual processing

Hate the Lakers? Do the Celtics make you want to hurl? Whether you like someone can affect how your brain processes their actions, according to new research from the Brain and Creativity Institute at USC.

6 Oct 2012

Gene-silencing mechanism may occur later in life and lead to cancer

There are some genes that are only activated in the very first days of an embryo's existence. Once they have accomplished their task, they are shut down forever, unlike most of our genes, which remain active throughout our lives. EPFL scientists have unveiled part of this strange mechanism. The same process, accidentally initiated later in life, could be responsible for many kinds of cancer.

6 Oct 2012

Study demonstrates efficacy of genotyping technology in identifying source of clinic infection outbreak

Researchers from East Carolina University used a new technique of genotyping to identify the source of a hematology clinic outbreak of Mycobacterium mucogenicum, a gram-positive, acid-fast bacteria found in tap water. This is the first outbreak of M. mucogenicum in an ambulatory care setting; five other outbreaks have been reported in hospital settings since 1995.

6 Oct 2012

Without B-Raf and C-Raf proteins mice's fur turns white

These proteins are required for melanocyte stem cell self-maintenance and, as such, correct pigmentation throughout the mice's life span. Without these two proteins, the mice's fur turns white. Their research is published in the review 'Cell Report' and paves the way for serious possibilities in terms of stopping the formation of melanomas, tumours that originate from melanocyte cells.

6 Oct 2012

NIH awards $2.1M grant to study possible ways to fight cancer

A professor with the University of Houston Cullen College of Engineering has won a $2.1 million grant to study the best ways to modify human immune cells to fight against cancer.

6 Oct 2012

Skin's outmost layer is the first line of defense against UV radiation

Reinhold Dauskardt, PhD, of Stanford's Department of Materials Science and Engineering has been studying skin for years. But when he sent his students to look for data on the mechanical properties of skin, they came back empty-handed. A lot was known about skin structure and disease, but few papers actually talked about its mechanical function - its ability to stretch and resist tension without tearing.

6 Oct 2012

BUSM leads genome-wide evaluation of genetic variants associated with Parkinson's disease

Boston University School of Medicine investigators have led the first genome-wide evaluation of genetic variants associated with Parkinson's disease (PD). The study, which is published online in PLOS ONE, points to the involvement of specific genes and alterations in their expression as influencing the risk for developing PD.

6 Oct 2012

Medical Science News

Study provides direct evidence for persistent activity in medial entorhinal cortex layer neurons

Researchers discover smallest and fastest-known RNA switches

NFKB1 gene variant may reduce risk of lung cancer

Researchers discover 8 new loci associated with susceptibility to atopic dermatitis

Researchers decipher how AP-1 gene regulator controls survival of liver tumor-initiating cells

Progenra’s USP7 and USP47 exert non-overlapping anticancer cell effects

New insight into basis of opiate addiction

CytoDyn announces update on feline immunodeficiency virus therapeutic antibody program

FDA clears Fenwal's new plasma products

New ways of how biological clock's neurons use electrical activity to keep behavioral rhythms in order

Researchers perfect map of vision in the brain based upon brain structure

Researchers identify mechanism that protects from developing uncontrollable fear

New light into evolution of human physiology and brain development

Social factors influence perceptual processing

Gene-silencing mechanism may occur later in life and lead to cancer

Study demonstrates efficacy of genotyping technology in identifying source of clinic infection outbreak

Without B-Raf and C-Raf proteins mice's fur turns white

NIH awards $2.1M grant to study possible ways to fight cancer

Skin's outmost layer is the first line of defense against UV radiation

BUSM leads genome-wide evaluation of genetic variants associated with Parkinson's disease

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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