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Small fragments of keratin protein in the eye play a key role in warding off pathogens

When it comes to germ-busting power, the eyes have it, according to a discovery by University of California, Berkeley, researchers that could lead to new, inexpensive antimicrobial drugs.

25 Sep 2012

Wiley announces publication of 6-volume Encyclopedia of Drug Metabolism and Interactions

Wiley is pleased to announce publication of the state-of-the-art, 6-volume Encyclopedia of Drug Metabolism and Interactions.

25 Sep 2012

UCLA/Pitt scientists uncover P. acnes virus with potential to kill zits

Watch out, acne. Doctors soon may have a new weapon against zits: a harmless virus living on our skin that naturally seeks out and kills the bacteria that cause pimples.

25 Sep 2012

Study uses white matter to study brain function

Most people equate "gray matter" with the brain and its higher functions, such as sensation and perception, but this is only one part of the anatomical puzzle inside our heads. Another cerebral component is the white matter, which makes up about half the brain by volume and serves as the communications network.

25 Sep 2012

Study unlocks secrets in bone marrow that could lead to improved treatments for colitis, Crohn's

Michigan State University researchers have unlocked secrets in bone marrow that could lead to improved treatments for colitis and Crohn's disease.

25 Sep 2012

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness in reversing memory loss in two animal models of Alzheimer's disease.

25 Sep 2012

New nanotechnology detects micrometastases in mouse models of breast cancer

Malignant cells that leave a primary tumor, travel the bloodstream and grow out of control in new locations cause the vast majority of cancer deaths. New nanotechnology developed at Case Western Reserve University detects these metastases in mouse models of breast cancer far earlier than current methods, a step toward earlier, life-saving diagnosis and treatment.

25 Sep 2012

Anti-androgen therapies may benefit bladder cancer patients

Bladder cancer patients whose tumors express high levels of the protein CD24 have worse prognoses than patients with lower CD24. A University of Colorado Cancer Center study published today in the Proceedings of the National Academy of Sciences shows that CD24 expression may depend on androgens - and that anti-androgen therapies like those currently used to treat prostate cancer may benefit bladder cancer patients.

25 Sep 2012

PAM50 potentially simplifies underlying breast tumor biology

On September 23, researchers published online in the journal Nature a study of the molecular biology of breast cancer, using the intrinsic subtypes as defined by the PAM50 gene signature as an organizing framework for analyzing genomic and proteomic aberrations. This landmark study both underscores the emergence of the intrinsic subtypes as a powerful taxonomy of breast cancer in research, and PAM50's role as the gold standard for categorizing breast cancer by subtype.

From NanoString Technologies 25 Sep 2012

Study tracks and compares brain growth in chimpanzee and human fetuses

Humans' superior brain size in comparison to their chimpanzee cousins traces all the way back to the womb. That's according to a study reported in the September 25 issue of Current Biology, a Cell Press publication, that is the first to track and compare brain growth in chimpanzee and human fetuses.

25 Sep 2012

Study on epigenetics link of PTSD and respiratory disease in 9/11 responders

The "Epigenetics Link of PTSD and Respiratory Disease in 9/11 Responders" study is the first to investigate the association between genetic changes and the development of both conditions in the 9/11 responder patient population. Approximately 500 patients treated at the LI-CCE for both conditions will be evaluated during the two-year study.

24 Sep 2012

Lasers manipulate neurons in worms' brains

In the quest to understand how the brain turns sensory input into behavior, Harvard scientists have crossed a major threshold. Using precisely-targeted lasers, researchers have been able to take over an animal's brain, instruct it to turn in any direction they choose, and even to implant false sensory information, fooling the animal into thinking food was nearby.

24 Sep 2012

Researchers identify gene linked to common cause of lower back pain

Researchers at King's College London have for the first time identified a gene linked to age-related degeneration of the intervertebral discs in the spine, a common cause of lower back pain.

24 Sep 2012

Conceptually novel mechanism for biological regulation of cell suicide

Death plays a big role in keeping things alive. Consider the tightly orchestrated suicide of cells--a phenomenon essential to everything from shaping an embryo to keeping it free of cancer later in life. When cells refuse to die, and instead multiply uncontrollably, they become what we call tumors. An intricate circuitry of biochemical reactions inside cells coordinates their self-sacrifice. Tracing that circuitry is, naturally, an important part of cancer research.

24 Sep 2012

Biologists unravel why some people infected with HIV have more virus

Biologists at UC San Diego have unraveled the anti-viral mechanism of a human gene that may explain why some people infected with HIV have much higher amounts of virus in their bloodstreams than others.

24 Sep 2012

Anesthetics and proteins: understanding the interactions

Spanish scientists at the University of the Basque Region and the University of La Rioja have combined mass-resolved electronic spectroscopy and ab initio calculations to model the interactions of anesthetics with proteins.

24 Sep 2012

NanoViricides’ oral FluCide dramatically improves survival in animals with H3N2 influenza A

NanoViricides, Inc. reported today that its oral FluCide drug candidates demonstrated dramatically improved survival in animals administered a lethal dose of the H3N2 influenza A virus.

24 Sep 2012

Cannabis Science commences CSTATI-1 preclinical studies in Squamous/BCCs, Kaposi's sarcoma

Cannabis Science, a pioneering U.S. Biotech Company developing pharmaceutical products for global public health challenges, is pleased to announce preclinical investigations being initiated in Europe for Squamous/Basal Cell carcinomas and Kaposi's sarcoma based on inhibition of carcinogenicity utilizing cannabinoids that have been demonstrated in recent studies to significantly affect tumor necrosis.

24 Sep 2012

PTEN inhibitor can trigger growth of small eggs

Researchers at the University of Gothenburg, Sweden, have discovered that a chemical can trigger the maturation of small eggs to healthy, mature eggs, a process that could give more women the chance of successful IVF treatment in the future. The results have been published in the revered journal PloS ONE.

24 Sep 2012

Molecular similarity between one sub-type of breast cancer and ovarian cancer

A team of scientists with The Cancer Genome Atlas program reports their genetic characterization of 800 breast tumors, including finding some of the genetic causes of the most common forms of breast cancer, providing clues for new therapeutic targets, and identifying a molecular similarity between one sub-type of breast cancer and ovarian cancer.

24 Sep 2012

Medical Science News

Small fragments of keratin protein in the eye play a key role in warding off pathogens

Wiley announces publication of 6-volume Encyclopedia of Drug Metabolism and Interactions

UCLA/Pitt scientists uncover P. acnes virus with potential to kill zits

Study uses white matter to study brain function

Study unlocks secrets in bone marrow that could lead to improved treatments for colitis, Crohn's

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

New nanotechnology detects micrometastases in mouse models of breast cancer

Anti-androgen therapies may benefit bladder cancer patients

PAM50 potentially simplifies underlying breast tumor biology

Study tracks and compares brain growth in chimpanzee and human fetuses

Study on epigenetics link of PTSD and respiratory disease in 9/11 responders

Lasers manipulate neurons in worms' brains

Researchers identify gene linked to common cause of lower back pain

Conceptually novel mechanism for biological regulation of cell suicide

Biologists unravel why some people infected with HIV have more virus

Anesthetics and proteins: understanding the interactions

NanoViricides’ oral FluCide dramatically improves survival in animals with H3N2 influenza A

Cannabis Science commences CSTATI-1 preclinical studies in Squamous/BCCs, Kaposi's sarcoma

PTEN inhibitor can trigger growth of small eggs

Molecular similarity between one sub-type of breast cancer and ovarian cancer

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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