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Experimental diabetes drug shows promise against Alzheimer's

A drug designed for diabetes sufferers could have the potential to treat neurodegenerative diseases like Alzheimer's, a study by scientists at the University of Ulster has revealed.

15 Sep 2012

A mysterious form of cell death uncovers prime suspect for new cancer drug development

A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.

15 Sep 2012

Genomes of lung cancer smokers have more mutations

Lung cancer patients with a history of smoking have 10 times more genetic mutations in their tumors than those with the disease who have never smoked, according to a new study from Washington University School of Medicine in St. Louis.

14 Sep 2012

Humans could learn from how plants handle stress

Humans could learn from how plants handle stress. Federica Brandizzi, Michigan State University plant biologist, is using a grant from the National Institutes of Health to study how plants overcome stress as they grow. These pathways used to overcome stress are a key to growth. Without them plants, and animals, would die.

14 Sep 2012

Scientists successfully reverse neuronal changes in autism

People with autism suffer from a pervasive developmental disorder of the brain that becomes evident in early childhood. Peter Scheiffele and Kaspar Vogt, Professors at the Biozentrum of the University of Basel, have identified a specific dysfunction in neuronal circuits that is caused by autism.

14 Sep 2012

Dual role of ghrelin in anxiety behavior is context-dependent

Ghrelin is a hormone released by the lining of the stomach that promotes feeding behavior. Decreasing ghrelin levels could potentially help combat obesity -- in fact, a vaccine that lowers ghrelin levels in order to reduce appetite is being studied as a treatment for obesity.

14 Sep 2012

Dynamic optical projection stereolithography can rapidly fabricate microscale 3D structures

Nanoengineers at the University of California, San Diego have developed a novel technology that can fabricate, in mere seconds, microscale three dimensional (3D) structures out of soft, biocompatible hydrogels.

14 Sep 2012

Researchers regenerate axons at spinal cord injury site

In a study at the University of California, San Diego and VA San Diego Healthcare, researchers were able to regenerate "an astonishing degree" of axonal growth at the site of severe spinal cord injury in rats.

14 Sep 2012

New links between ghrelin and brain cells involved in development of alcoholism

Researchers at The Scripps Research Institute have found new links between a protein that controls our urge to eat and brain cells involved in the development of alcoholism. The discovery points to new possibilities for designing drugs to treat alcoholism and other addictions.

14 Sep 2012

Researchers clone T-cell receptor that binds to antigens associated with prostate and breast cancer

Researchers at Uppsala University have cloned a T-cell receptor that binds to an antigen associated with prostate cancer and breast cancer. T cells that have been genetically equipped with this T-cell receptor have the ability to specifically kill prostate and breast cancer cells.

14 Sep 2012

UMass Amherst develops 'chemical nose' array to detect metastatic cancers

In the fight against cancer, knowing the enemy's exact identity is crucial for diagnosis and treatment, especially in metastatic cancers, those that spread between organs and tissues. Now chemists led by Vincent Rotello at the University of Massachusetts Amherst have developed a rapid, sensitive way to detect microscopic levels of many different metastatic cell types in living tissue. Findings appear in the current issue of the journal ACS Nano.

14 Sep 2012

HIF-1a protein of hypoxia creates CD24 overexpression in many tumors

It seems as if a tumor deprived of oxygen would shrink. However, numerous studies have shown that tumor hypoxia, in which portions of the tumor have significantly low oxygen concentrations, is in fact linked with more aggressive tumor behavior and poorer prognosis.

14 Sep 2012

Study: 172K polymorphism makes certain forms of HIV less resistant to drugs

The human immunodeficiency virus (HIV) can contain dozens of different mutations, called polymorphisms. In a recent study an international team of researchers, including MU scientists, found that one of those mutations, called 172K, made certain forms of the virus more susceptible to treatment. Soon, doctors will be able to use this knowledge to improve the drug regiment they prescribe to HIV-infected individuals.

14 Sep 2012

Scientists describe how DNA origami can enhance effect of cytostatics in cancer treatment

Scientists at Karolinska Institutet in Sweden describe in a new study how so-called DNA origami can enhance the effect of certain cytostatics used in the treatment of cancer. With the aid of modern nanotechnology, scientists can target drugs direct to the tumour while leaving surrounding healthy tissue untouched.

14 Sep 2012

Researchers hold new implications for pathogenesis of myotonic dystrophy

An important breakthrough could help in the fight against myotonic dystrophy. The discovery, recently published in the prestigious scientific journal Cell, results from an international collaboration between researchers at the IRCM, the Massachusetts Institute of Technology (MIT), the University of Southern California and Illumina.

13 Sep 2012

Treating elderly patients with elevated thyroid-stimulating hormone levels may be unnecessary

There is no evidence to link mildly elevated thyroid-stimulating hormone (TSH) levels to an increase in mortality among the elderly, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

13 Sep 2012

Changes in Troponin I protein can lead to cardiac muscle malfunction and precipitate heart failure

A new Johns Hopkins study has unraveled the changes in a key cardiac protein that can lead to heart muscle malfunction and precipitate heart failure.

13 Sep 2012

Pam2Cys nasal spray may be useful agent against pandemics and emerging viral strains

In an advance toward development of a nasal spray that protects against infection with influenza and spread of the disease, scientists are reporting identification of a substance that activates the first-line defense system against infection inside the nose. They describe effects of a synthetic form of a natural substance found in bacterial cell walls in ACS' journal Molecular Pharmaceutics.

13 Sep 2012

Sanford-Burnham professor to develop personalized models of inherited heart conditions

The California Institute for Regenerative Medicine (CIRM) has awarded a $1.58 million grant to Huei-Sheng Vincent Chen, Ph.D., associate professor at Sanford-Burnham Medical Research Institute (Sanford-Burnham). Chen's proposal was one of 28 new projects funded as part of CIRM's Basic Biology IV awards program, which supports basic research aimed at increasing our understanding of stem cells and how to work with them.

13 Sep 2012

ICREA researcher updates latest findings in applied epigenetics

The research team led by Manel Esteller, director of the Cancer Epigenetics and Biology Program at the Bellvitge Biomedical Research Institute (IDIBELL), professor of genetics at the University of Barcelona and ICREA researcher, has updated the latest findings in applied epigenetics in a review paper published in Nature Reviews Genetics.

13 Sep 2012

Medical Science News

Experimental diabetes drug shows promise against Alzheimer's

A mysterious form of cell death uncovers prime suspect for new cancer drug development

Genomes of lung cancer smokers have more mutations

Humans could learn from how plants handle stress

Scientists successfully reverse neuronal changes in autism

Dual role of ghrelin in anxiety behavior is context-dependent

Dynamic optical projection stereolithography can rapidly fabricate microscale 3D structures

Researchers regenerate axons at spinal cord injury site

New links between ghrelin and brain cells involved in development of alcoholism

Researchers clone T-cell receptor that binds to antigens associated with prostate and breast cancer

UMass Amherst develops 'chemical nose' array to detect metastatic cancers

HIF-1a protein of hypoxia creates CD24 overexpression in many tumors

Study: 172K polymorphism makes certain forms of HIV less resistant to drugs

Scientists describe how DNA origami can enhance effect of cytostatics in cancer treatment

Researchers hold new implications for pathogenesis of myotonic dystrophy

Treating elderly patients with elevated thyroid-stimulating hormone levels may be unnecessary

Changes in Troponin I protein can lead to cardiac muscle malfunction and precipitate heart failure

Pam2Cys nasal spray may be useful agent against pandemics and emerging viral strains

Sanford-Burnham professor to develop personalized models of inherited heart conditions

ICREA researcher updates latest findings in applied epigenetics

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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