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Researchers discover genetic cause of hereditary spastic ataxia

Researchers from the Guy Rouleau Laboratory affiliated with the CHUM Research Centre and the CHU-Sainte-Justine Research Centre have discovered the genetic cause of a rare disease reported only in patients originating from Newfoundland: hereditary spastic ataxia (HSA).

7 Sep 2012

Harvard experts create biocompatible hydrogel

A team of experts in mechanics, materials science, and tissue engineering at Harvard have created an extremely stretchy and tough gel that may pave the way to replacing damaged cartilage in human joints.

6 Sep 2012

JQ1 compound dramatically prevents sperm production in mice

Attention men: The day may be coming soon when you can take your own birth control pill with no side effects, according to a study done by a group of scientists that includes a Texas A&M University researcher.

6 Sep 2012

Ingenuity Systems, ShanghaiBio sign collaboration agreement

ShanghaiBio Corporation and Ingenuity Systems have signed a collaboration agreement enabling ShanghaiBio Corporation to extend its current lab service offering to include Ingenuity solutions for downstream analysis and interpretation of genomics data. ShanghaiBio Corporation will complement their sequencing, genotyping and gene expression lab services by creating a bundled solution with Ingenuity's applications, which combine analytics and biomedical content to help get actionable insights from experiments.

6 Sep 2012

Injecting capsule with heat-generating cells reduces abdominal and belly fat in mice

The injection of a tiny capsule containing heat-generating cells into the abdomens of mice led those animals to burn abdominal fat and initially lose about 20 percent of belly fat after 80 days of treatment.

6 Sep 2012

Scientists complete comprehensive map of genetic mutations linked to small cell lung cancers

Scientists have completed a comprehensive map of genetic mutations linked to an aggressive and lethal type of lung cancer.

6 Sep 2012

New approach can help researchers study genetic variations associated with disease

With the ability to sequence human genes comes an onslaught of raw material about the genetic characteristics that distinguish us, and wading through these reserves of data poses a major challenge for life scientists. Researchers at Roswell Park Cancer Institute (RPCI) and the Center for Human Genome Variation at Duke University Medical Center (DUMC) have developed an approach for analyzing data that can help researchers studying genetic factors in disease to quickly cull out relevant genetic patterns and identify variants that lead to particular disorders.

6 Sep 2012

Tampere University of Technology to construct human 3D neuronal structure

European Commission's Future and Emerging Technologies (FET) scheme has granted 4 M- to an international consortium aiming to construct a functional 3D neuronal structure mimicking the human brain. The project titled "Biomimicking the brain - towards 3D neuronal network dynamics" is planned to last for the period 1.7.2012.12.2014.

6 Sep 2012

Eliminating jnk3 enzyme leads to 90% reduction in Alzheimer's plaque-forming compounds

Scientists have found that eliminating an enzyme from mice with symptoms of Alzheimer's disease leads to a 90 percent reduction in the compounds responsible for formation of the plaques linked to Alzheimer's disease.

6 Sep 2012

Sleep disruptions may be among the first signs of Alzheimer's

Sleep disruptions may be among the earliest indicators of Alzheimer's disease, scientists at Washington University School of Medicine in St. Louis report Sept. 5 in Science Translational Medicine.

6 Sep 2012

Study sheds light on why women gain fat following menopause

A high-fat diet triggers chemical reactions in female mice that could explain why women are more likely than men to gain fat in the abdomen after eating excess saturated fat, new research suggests. The study also sheds light on why women gain fat following menopause.

6 Sep 2012

Researchers identify HIF2α gene mutation in cancer tumor cells

For the first time, a mutation in HIF2α, a specific group of genes known as transcription factors that is involved in red blood cell production and cell metabolism, has been identified in cancer tumor cells.

6 Sep 2012

Congressional champion for brain science research issues statement in response to $30M NFL grant

Congressman Chaka Fattah (D-PA), the Congressional champion for brain science research and author of the Fattah Neuroscience Initiative, issues this statement in response to today's $30 million grant by the National Football League to the Foundation for the National Institutes of Health.

6 Sep 2012

CSHL publishes genome-wide analysis of transcripts produced within human cells

Most people understand genes to be specific segments of DNA that determine traits or diseases that are inherited. Textbooks suggest that genes are copied into RNA molecules, which are then used as templates for making protein - the highly diverse set of molecules that act as building blocks and engines of our cells. The truth, it now appears, is not so simple.

6 Sep 2012

CHOP’s Center for Autism Research receives ACE grant to identify early signs of ASD

The Center for Autism Research at The Children's Hospital of Philadelphia (CHOP) announced today that it will continue its research to identify early signs of autism spectrum disorders (ASD) through a grant from the National Institutes of Health (NIH) Autism Centers of Excellence (ACE) research program.

6 Sep 2012

Book on basic stereology for biologists and neuroscientists

Stereological techniques allow biologists to create quantitative, three-dimensional descriptions of biological structures from two-dimensional images of tissue viewed under the microscope. For example, they can accurately estimate the size of a particular subcellular compartment, the total length of a mass of blood vessels, or the number of neurons or synapses in a particular region of the brain.

6 Sep 2012

Teenage brains being changed by the digital revolution

The digital revolution appears to be changing the adolescent brain to enable it to cope with constant technological stimulation, says visiting U.S. adolescent brain researcher Dr Jay Giedd.

6 Sep 2012

Janssen, ImmuNext partner to develop novel cancer therapeutics

ImmuNext, Inc., today announced that it has entered into an agreement with Janssen Biotech, Inc., focused on the development of novel therapeutics that modulate the immune system for the treatment of cancer.

6 Sep 2012

Scripps Florida designs new compound that shows promise against tremor ataxia syndrome

Scientists on the Florida campus of The Scripps Research Institute have designed a compound that shows promise as a potential therapy for one of the diseases closely linked to fragile X syndrome, a genetic condition that causes mental retardation, infertility, and memory impairment, and is the only known single-gene cause of autism.

6 Sep 2012

Akonni receives NSF's Phase 2 SBIR Grant to develop Lab-on-a-Film microarray

Akonni Biosystems, a life science tools / molecular diagnostics company that develops, manufactures, and plans to market molecular testing devices for diagnosing infectious diseases and human genetic disorders, announced today the receipt of a $498,780 Phase 2 SBIR Grant from the National Science Foundation (NSF).

6 Sep 2012

Medical Science News

Researchers discover genetic cause of hereditary spastic ataxia

Harvard experts create biocompatible hydrogel

JQ1 compound dramatically prevents sperm production in mice

Ingenuity Systems, ShanghaiBio sign collaboration agreement

Injecting capsule with heat-generating cells reduces abdominal and belly fat in mice

Scientists complete comprehensive map of genetic mutations linked to small cell lung cancers

New approach can help researchers study genetic variations associated with disease

Tampere University of Technology to construct human 3D neuronal structure

Eliminating jnk3 enzyme leads to 90% reduction in Alzheimer's plaque-forming compounds

Sleep disruptions may be among the first signs of Alzheimer's

Study sheds light on why women gain fat following menopause

Researchers identify HIF2α gene mutation in cancer tumor cells

Congressional champion for brain science research issues statement in response to $30M NFL grant

CSHL publishes genome-wide analysis of transcripts produced within human cells

CHOP’s Center for Autism Research receives ACE grant to identify early signs of ASD

Book on basic stereology for biologists and neuroscientists

Teenage brains being changed by the digital revolution

Janssen, ImmuNext partner to develop novel cancer therapeutics

Scripps Florida designs new compound that shows promise against tremor ataxia syndrome

Akonni receives NSF's Phase 2 SBIR Grant to develop Lab-on-a-Film microarray

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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