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Scientists establish genetic mouse model for primary ovarian insufficiency

Scientists have established a genetic mouse model for primary ovarian insufficiency (POI), a human condition in which women experience irregular menstrual cycles and reduced fertility, and early exposure to estrogen deficiency.

31 Aug 2012

S107 drug can prevent learning and memory deficits associated with stress-related disorders

Columbia University Medical Center (CUMC) researchers have identified a potential medical treatment for the cognitive effects of stress-related disorders, including post-traumatic stress disorder (PTSD).

31 Aug 2012

Type 2 diabetics with normoalbuminuria more likely to develop heart problems

In individuals with type 2 diabetes, any degree of measurable urinary protein excretion—even in what is considered the normal range—increases their risk of experiencing heart problems, according to a study appearing in an upcoming issue of new study in the Journal of the American Society of Nephrology (JASN).

31 Aug 2012

Weill Cornell Medical College receives three new research grants for translational blood cancer study

Weill Cornell Medical College has been awarded three new research grants from the Leukemia & Lymphoma Society totaling $1.8 million. The funds will support critically-needed translational research for blood cancers, accelerating promising discoveries from the laboratory to the patient's bedside.

31 Aug 2012

Healthy diets during infancy and early childhood can prevent obesity in future

Rats born to mothers fed high-fat diets but who get normal levels of fat in their diets right after birth avoid obesity and its related disorders as adults, according to new Johns Hopkins research.

31 Aug 2012

Soligenix’s RiVax induces greater ricin neutralizing antibody levels in humans

Soligenix, Inc., a development stage biopharmaceutical company, announced today the results of a Phase 1B clinical trial of an aluminum hydroxide (Alum) adjuvanted formulation of RiVax, designed to improve the immunogenicity of the vaccine.

31 Aug 2012

Researchers discover new immune response mechanism during infection

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a new "first response" mechanism that the immune system uses to respond to infection. The findings challenge the current understanding of immunity and could lead to new strategies for boosting effectiveness of all vaccines. The study, conducted in mice, published online today in the journal Immunity.

31 Aug 2012

Studies examine how PML gene regulates the fatty acid oxidation pathway

Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, highlight both the challenges and opportunities of genetic approaches to cancer treatment.

31 Aug 2012

Study explains how FPGS increases effectiveness of pemetrexed in mesothelioma patients

Previous studies have hypothesized that low levels of the enzyme thymidylate synthase (TS) likely mark patients who will benefit from the drug pemetrexed - but results have been inconclusive at best and at times contradictory. A University of Colorado Cancer Center study recently published in the Journal of Thoracic Oncology provides an explanation why: only in combination with high levels of a second enzyme, FPGS, does low TS predict response to pemetrexed in patients with malignant pleural mesothelioma.

31 Aug 2012

Scientists open new front against cause of sleeping sickness

Scientists of the Antwerp Institute of Tropical Medicine (ITG) opened a new front against the cause of sleeping sickness. This parasite is transmitted between humans by tsetse flies. The researchers learned a bacterium living in those flies how to produce antibodies against the parasite. Application in the field is still a long way of, but the technique shows quite some promise.

31 Aug 2012

Researchers discover how tamoxifen-resistant breast-cancer cells grow and proliferate

A study by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has discovered how tamoxifen-resistant breast-cancer cells grow and proliferate.

31 Aug 2012

Quest Diagnostics announces availability of TERC test for cervical cancer

Quest Diagnostics, the world's leading provider of diagnostic testing, information and services, today announced the availability of a new laboratory test that identifies molecular changes to cervical cells that increase the likelihood a woman may develop cervical cancer.

From Quest Diagnostics 31 Aug 2012

PD0325901 drug may hold potential to prevent neurofibromatosis 1 in children

A drug originally developed to stop cancerous tumors may hold the potential to prevent abnormal brain cell growth and learning disabilities in some children, if they can be diagnosed early enough, a new animal study suggests.

31 Aug 2012

Grb10 plays a crucial role in increasing muscle mass during development

Scientists have moved closer toward helping people grow big, strong muscles without needing to hit the weight room. Australian researchers have found that by blocking the function of a protein called Grb10 while mice were in the womb, they were considerably stronger and more muscular than their normal counterparts.

31 Aug 2012

DNA synthesis in the 3’ and 5’ direction possible using new template-directed method

When a cell divides, it passes on genetic information by producing copies of its DNA. Chemists have also learned to copy DNA. In the journal Angewandte Chemie, a German team has now introduced a new copying technique that uses a single strand of DNA as the “master copy”, like a cell, but does not require enzymes.

30 Aug 2012

Stowers investigators define factors that regulate size of cellular fat pools

As the national waistline expands, so do pools of intra-cellular fat known as lipid droplets. Although most of us wish our lipid droplets would vanish, they represent a cellular paradox: on the one hand droplets play beneficial roles by corralling fat into non-toxic organelles. On the other, oversized lipid droplets are associated with obesity and its associated health hazards.

30 Aug 2012

Strong neural communication between the hemispheres predicts math performance

A new study by researchers at UT Dallas' Center for Vital Longevity, Duke University, and the University of Michigan has found that the strength of communication between the left and right hemispheres of the brain predicts performance on basic arithmetic problems. The findings shed light on the neural basis of human math abilities and suggest a possible route to aiding those who suffer from dyscalculia-- an inability to understand and manipulate numbers.

30 Aug 2012

New York State Department of Health issues license to Veracyte's Afirma Gene Expression Classifier

Veracyte, Inc., a molecular diagnostics company pioneering the emerging field of molecular cytology, and Genzyme, a Sanofi company, today announced that the New York State Department of Health has issued a license enabling Veracyte's Afirma Gene Expression Classifier to be offered to patients in the state.

30 Aug 2012

MU medicinal chemists create more potent, efficient weapon against cancer

Legend has it that Ralph Waldo Emerson once said, "Build a better mousetrap, and the world will beat a path to your door." University of Missouri researchers are doing just that, but instead of building mousetraps, the scientists are targeting cancer drugs. In a new study, MU medicinal chemists have taken an existing drug that is being developed for use in fighting certain types of cancer, added a special structure to it, and created a more potent, efficient weapon against cancer.

30 Aug 2012

University of Adelaide researchers to produce better quality pasta with health properties

University of Adelaide researchers are working with colleagues in Italy to produce better quality pasta that also adds greater value to human health.

30 Aug 2012

Medical Science News

Scientists establish genetic mouse model for primary ovarian insufficiency

S107 drug can prevent learning and memory deficits associated with stress-related disorders

Type 2 diabetics with normoalbuminuria more likely to develop heart problems

Weill Cornell Medical College receives three new research grants for translational blood cancer study

Healthy diets during infancy and early childhood can prevent obesity in future

Soligenix’s RiVax induces greater ricin neutralizing antibody levels in humans

Researchers discover new immune response mechanism during infection

Studies examine how PML gene regulates the fatty acid oxidation pathway

Study explains how FPGS increases effectiveness of pemetrexed in mesothelioma patients

Scientists open new front against cause of sleeping sickness

Researchers discover how tamoxifen-resistant breast-cancer cells grow and proliferate

Quest Diagnostics announces availability of TERC test for cervical cancer

PD0325901 drug may hold potential to prevent neurofibromatosis 1 in children

Grb10 plays a crucial role in increasing muscle mass during development

DNA synthesis in the 3’ and 5’ direction possible using new template-directed method

Stowers investigators define factors that regulate size of cellular fat pools

Strong neural communication between the hemispheres predicts math performance

New York State Department of Health issues license to Veracyte's Afirma Gene Expression Classifier

MU medicinal chemists create more potent, efficient weapon against cancer

University of Adelaide researchers to produce better quality pasta with health properties

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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