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Addiction to morphine and heroin can be blocked via brain's immune response

In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.

15 Aug 2012

Novel device provides retina's neural code to restore normal vision

Two researchers at Weill Cornell Medical College have deciphered a mouse's retina's neural code and coupled this information to a novel prosthetic device to restore sight to blind mice.

15 Aug 2012

Blocking PHD2 oxygen sensor can render cancer treatments more effective

Researchers in Leuven (VIB/KU Leuven) have confirmed their hypothesis that normalizing blood vessels by blocking oxygen sensor PHD2 would make chemotherapy more effective.

15 Aug 2012

Study examines shared traits of cancer cells and bacteria

Experts agree that, more than ever before, modern wars will be fought in the cyber zone, targeting an enemy's communications technology to cause untold damage. Now a Tel Aviv University researcher is suggesting that the same tactics should be employed in the battle against one of the body's deadliest enemies - cancer.

15 Aug 2012

U of U researchers receive NIH grant to study cellular and molecular causes of blood clots

University of Utah Department of Medicine researchers have received $16 million from the National Institutes of Health (NIH) to set up a translational research center to study the cellular and molecular causes of blood clots, a serious threat to millions of people who have diabetes, are obese or have other metabolic disorders.

15 Aug 2012

Mindfulness meditation prevents feelings of loneliness

Many elderly people spend their last years alone. Spouses pass and children scatter. But being lonely is much more than a silent house and a lack of companionship. Over time, loneliness not only takes a toll on the psyche but can have a serious physical impact as well.

15 Aug 2012

Two papers may help identify gene variants that contribute to OCD or Tourette syndrome

Two papers that will appear in the journal Molecular Psychiatry, both receiving advance online release, may help identify gene variants that contribute to the risks of developing obsessive-compulsive disorder (OCD) or Tourette syndrome (TS). Both multi-institutional studies were led by Massachusetts General Hospital (MGH) investigators, and both are the first genome-wide association studies (GWAS) in the largest groups of individuals affected by the conditions.

15 Aug 2012

Combination of obatoclax and flavopiridol triggers multiple myeloma cell death

Researchers at Virginia Commonwealth University Massey Cancer Center are reporting promising results from laboratory and animal experiments involving a new combination therapy for multiple myeloma, the second most common form of blood cancer.

15 Aug 2012

CD4 T cells orchestrate inflammatory attack on the artery wall

Most people probably know that heart disease remains the nation's No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune system.

15 Aug 2012

Catechins may help reduce neurological complications linked to HIV

Current drug therapy for patients with HIV is unable to control the complete replication of the virus in the brain. The drugs therefore do not have any effect against the complications associated with neurocognitive impairment in patients with HIV. New research by Joseph Steiner and colleagues from Johns Hopkins University has discovered that a group of plant polyphenols known as catechins, which naturally occur in green tea and the seed of the cacao tree, may help in the prevention of these neurological complications.

15 Aug 2012

Study investigates ability of bifidobacteria to remove glycans from milk glycoproteins

A research team at the University of California, Davis, has found that important and resourceful bacteria in the baby microbiome can ferret out nourishment from a previously unknown source, possibly helping at-risk infants break down components of breast milk.

15 Aug 2012

Glioblastoma patients with modified PTEN have resistance to EGFR inhibitors

Despite years of research, glioblastoma, the most common and deadly brain cancer in adults, continues to outsmart treatments targeted to inhibit tumor growth.

15 Aug 2012

Scientists use supercomputers to reveal links between known risk factors and heart biology

About 25,000 Danes currently live with congenital heart defects. Both heredity and environment play a role for these malformations, but exactly how various risk factors influence the development of the heart during pregnancy has been a mystery until now.

15 Aug 2012

Cathepsins may attack one another instead of the bodily proteins

Researchers for the first time have shown that members of a family of enzymes known as cathepsins - which are implicated in many disease processes - may attack one another instead of the bodily proteins they normally degrade. Dubbed "cathepsin cannibalism," the phenomenon may help explain problems with drugs that have been developed to inhibit the effects of these powerful proteases.

15 Aug 2012

Protein folding: Nobel laureate Ahmed H. Zewail summarizes his insights

Living subjects are very complex systems and, at the same time, stunningly robust and accommodative. The secret of success are their proteins which build up the cells of the organisms, act as cleaners, messengers, transporter, motors, and fulfill much more jobs. How proteins are genetically coded and how their linear chains of amino acids are put together, is in principle well known.

14 Aug 2012

Schizophrenia and the immune system: an interview with Prof Cyndi Shannon Weickert

Schizophrenia is the most disabling disease impacting youth today. It impacts 1% of the total population and typically causes withdrawal from society, loss in IQ, disordered thought and speech, hallucinations and delusions.

14 Aug 2012

Portable aspiration system for disposal of liquid biological waste

The VACUSIP from INTEGRA provides an ideal benchtop solution for the safe aspiration and disposal of small volumes of liquid waste in clinical, molecular biology, biochemistry and microbiology labs.

From INTEGRA Biosciences 14 Aug 2012

Latrepiridine reduces level of at least two neurodegeneration-related proteins in mice

The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions.

14 Aug 2012

External stimulation impacts postnatal development of brain's white matter

A team at Children's National Medical Center has found that external stimulation has an impact on the postnatal development of a specific region of the brain. Published in Nature Neuroscience, the study used sensory deprivation to look at the growth and collection of NG2-expressing oligodendrocyte progenitor cells (NG2 cells) in the sensory cortex of the brain.

14 Aug 2012

Antisense therapy shows promise in treating toxoplasmosis

A targeted approach to treating toxoplasmosis, a parasitic disease, shows early promise in test-tube and animal studies, where it prevented the parasites from making selected proteins. When tested in newly infected mice, it reduced the number of viable parasites by more than 90 percent, researchers from the University of Chicago Medicine report in the Proceedings of the National Academy of Sciences.

14 Aug 2012

Medical Science News

Addiction to morphine and heroin can be blocked via brain's immune response

Novel device provides retina's neural code to restore normal vision

Blocking PHD2 oxygen sensor can render cancer treatments more effective

Study examines shared traits of cancer cells and bacteria

U of U researchers receive NIH grant to study cellular and molecular causes of blood clots

Mindfulness meditation prevents feelings of loneliness

Two papers may help identify gene variants that contribute to OCD or Tourette syndrome

Combination of obatoclax and flavopiridol triggers multiple myeloma cell death

CD4 T cells orchestrate inflammatory attack on the artery wall

Catechins may help reduce neurological complications linked to HIV

Study investigates ability of bifidobacteria to remove glycans from milk glycoproteins

Glioblastoma patients with modified PTEN have resistance to EGFR inhibitors

Scientists use supercomputers to reveal links between known risk factors and heart biology

Cathepsins may attack one another instead of the bodily proteins

Protein folding: Nobel laureate Ahmed H. Zewail summarizes his insights

Schizophrenia and the immune system: an interview with Prof Cyndi Shannon Weickert

Portable aspiration system for disposal of liquid biological waste

Latrepiridine reduces level of at least two neurodegeneration-related proteins in mice

External stimulation impacts postnatal development of brain's white matter

Antisense therapy shows promise in treating toxoplasmosis

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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