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WUSM receives NHLBI grant to study heart disease in patients with diabetes

Researchers at Washington University School of Medicine in St. Louis have received a $4.7 million grant from the National Heart, Lung, and Blood Institute to investigate heart disease in patients with diabetes.

14 Jul 2012

Obesity-fighting tissue in humans is actually not quite brown, says study

The calorie-burning and heat-generating brown fat found in full-grown humans is actually not quite brown; it's beige. So says a new study reported on July 12th in the journal Cell, a Cell Press publication, in which researchers fully characterize this promising obesity-fighting tissue in both mice and humans for the first time.

14 Jul 2012

Researchers identify potassium channel as an autoantibody target in MS

For the first time, scientists in Germany's multiple sclerosis competence network have been able to identify an antibody that bonds with the potassium channel KIR4.1.

14 Jul 2012

Researchers define interaction between two essential proteins that control inflammation

Researchers at the IRCM, led by geneticist Dr. Jacques Drouin, recently defined the interaction between two essential proteins that control inflammation.

14 Jul 2012

Five rare mutations in single gene increase chances of boys developing ASD

Researchers at Emory University School of Medicine have identified five rare mutations in a single gene that appear to increase the chances that a boy will develop an autism spectrum disorder (ASD).

13 Jul 2012

Scientists isolate new type of energy-burning fat cell

Scientists at Dana-Farber Cancer Institute have isolated a new type of energy-burning fat cell in adult humans which they say may have therapeutic potential for treating obesity.

13 Jul 2012

Discovery sheds light on why human body is unable to fight off HIV infection

University of Washington researchers have made a discovery that sheds light on why the human body is unable to adequately fight off HIV infection.

13 Jul 2012

UC Davis, CDC, Agilent and FDA partner to develop public database of foodborne pathogen genomes

The U.S. Food and Drug Administration (FDA), the University of California, Davis, Agilent Technologies Inc., and the Centers for Disease Control and Prevention (CDC) announced today a collaboration to create a public database of 100,000 foodborne pathogen genomes to help speed identification of bacteria responsible for foodborne outbreaks.

12 Jul 2012

Eisai, Verastem partner for next-generation of small molecule Wnt inhibitors

Verastem, Inc., a biopharmaceutical company focused on discovering and developing drugs to treat breast and other cancers by targeting cancer stem cells, announced a research collaboration with Eisai for the next-generation of small molecule Wnt inhibitors.

12 Jul 2012

Superorganism view of the human body

Amid the growing recognition that only a small fraction of the cells and genes in a typical human being are human, scientists are suggesting a revolutionary approach to developing new medicines and treatments to target both the human and non-human components of people. That's the topic of an article, which reviews work relating to this topic from almost 100 studies, in ACS' Journal of Proteome Research.

12 Jul 2012

PGC-1alpha and TFEB provide two new therapeutic targets for Huntington's disease

In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critical to clearing away misfolded proteins that accumulate and cause the progressive, deadly neurodegeneration of Huntington's disease.

12 Jul 2012

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

A research team in the United Kingdom has found that insulin-like growth factor (IGF1) impacts cell transplantation of photoreceptor precursors by manipulating the retinal recipient microenvironment, enabling better migration and integration of the cells into the adult mouse retina.

12 Jul 2012

SLU professor to study how antithrombin might prevent premature death from heart disease

Alireza "Ray" Rezaie, Ph.D., professor of biochemistry and molecular biology at Saint Louis University School of Medicine, has received a $1.52 million NIH grant to study how the key blood clotting inhibitor antithrombin might be exploited to prevent premature death from heart disease.

12 Jul 2012

Scientists assemble timeline of brain changes that lead to Alzheimer's

Scientists have assembled the most detailed chronology to date of the human brain's long, slow slide into full-blown Alzheimer's disease.

12 Jul 2012

Communication between brain and muscle cells is short-lived without LRP4 protein

Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues to ensure the conversation is robust.

12 Jul 2012

BGI, BioMed Central launch GigaScience journal

BGI, the world's largest genome sequencing institute, and their publishing partner BioMed Central, a leader in scientific data sharing, announce the launch of a new journal, GigaScience, which publishes large-scale biological research in a unique format.

12 Jul 2012

Researchers identify set of laboratory-based biomarkers that aid in diagnosis of schizophrenia

In the current online issue of PLoS ONE, researchers at the University of California, San Diego School of Medicine say they have identified a set of laboratory-based biomarkers that can be useful for understanding brain-based abnormalities in schizophrenia. The measurements, known as endophenotypes, could ultimately be a boon to clinicians who sometimes struggle to recognize and treat the complex and confounding mental disorder.

12 Jul 2012

Medical Science News

WUSM receives NHLBI grant to study heart disease in patients with diabetes

Obesity-fighting tissue in humans is actually not quite brown, says study

Researchers identify potassium channel as an autoantibody target in MS

Researchers define interaction between two essential proteins that control inflammation

Five rare mutations in single gene increase chances of boys developing ASD

Scientists isolate new type of energy-burning fat cell

Discovery sheds light on why human body is unable to fight off HIV infection

UC Davis, CDC, Agilent and FDA partner to develop public database of foodborne pathogen genomes

Eisai, Verastem partner for next-generation of small molecule Wnt inhibitors

Superorganism view of the human body

PGC-1alpha and TFEB provide two new therapeutic targets for Huntington's disease

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

SLU professor to study how antithrombin might prevent premature death from heart disease

Scientists assemble timeline of brain changes that lead to Alzheimer's

Communication between brain and muscle cells is short-lived without LRP4 protein

BGI, BioMed Central launch GigaScience journal

Researchers identify set of laboratory-based biomarkers that aid in diagnosis of schizophrenia

Cellular change also occurs in early-stage lung cancer, say researchers

TGen's customized procedure produces high amounts of exosomes for treatment of CKD

Eschar-derived cells may be used for tissue engineering

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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