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Scientists discover new signalling pathway that controls both obesity and atherosclerosis

A*STAR scientists from the Institute of Molecular and Cell Biology (IMCB) and the Singapore Bioimaging Consortium (SBIC) have discovered a new signalling pathway that controls both obesity and atherosclerosis.

6 Jul 2012

Scientists use antibody injections to rapidly reverse onset of Type I diabetes in mice

Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections maintained disease remission indefinitely without harming the immune system.

6 Jul 2012

Reprogramming asthma-promoting immune cells diminishes airway damage and inflammation

Reprogramming asthma-promoting immune cells in mice diminishes airway damage and inflammation, and could potentially lead to new treatments for people with asthma, researchers have found.

5 Jul 2012

Cancer Therapeutics announces validation and performance of CTx-294886 plus Avastin

Cancer Therapeutics, a company focused on translating cancer biology research into novel treatments for cancer, today announced the validation and performance of a new targeted drug, CTx-294886, in combination with Avastin (bevacizumab - Genentech/Roche) in a preclinical model of breast cancer.

5 Jul 2012

Scientists discover constant cloud of potent inflammatory molecules surrounding the monocytes

Scientists at the University of East Anglia (UEA) have discovered a 'constant cloud' of potent inflammatory molecules surrounding the cells responsible for diseases such as thickening of the arteries and rheumatoid arthritis.

5 Jul 2012

Study shows cells from different Parkinson’s patients have unique drug responses

Researchers have taken a step toward personalized medicine for Parkinson's disease, by investigating signs of the disease in patient-derived cells and testing how the cells respond to drug treatments.

5 Jul 2012

Eltrombopag can raise blood cell levels in some people with severe aplastic anemia

Eltrombopag, a drug that was designed to stimulate production of platelets from the bone marrow and thereby improve blood clotting, can raise blood cell levels in some people with severe aplastic anemia who have failed all standard therapies.

5 Jul 2012

Neighboring non-cancer cells may contribute to drug resistance

One of cancer's most frightening characteristics is its ability to return after treatment. In the case of many forms of cancer, including the skin cancer known as melanoma, tailored drugs can eradicate cancer cells in the lab, but often produce only partial, temporary responses in patients. One of the burning questions in the field of cancer research has been and remains: how does cancer evade drug treatment?

5 Jul 2012

Researchers use maternal blood sample to sequence genome of an unborn baby

Researchers at the Stanford University School of Medicine have for the first time sequenced the genome of an unborn baby using only a blood sample from the mother.

5 Jul 2012

Interfascicular matrix essential for tendon function

Tendon disorders cost the UK economy more than -7bn a year and now scientists at Queen Mary, University of London have identified a vital component of tendons which could help treat them.

5 Jul 2012

Lower pH reduces ability of ASL to kill bacteria in CF airways

The human airway is a pretty inhospitable place for microbes. There are numerous immune defense mechanisms poised to kill or remove inhaled bacteria before they can cause problems. But cystic fibrosis (CF) disrupts these defenses, leaving patients particularly susceptible to airway infection, which is the major cause of disease and death in CF.

5 Jul 2012

Scientists identify causative link between oncometabolite and onset of AML

A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme and the onset of acute myeloid leukemia (AML), one of the most common types of leukemia in adults.

5 Jul 2012

Alcoholic liver disease risk only ‘modestly’ affected by genetic factors

Research has suggested that environmental factors have a greater impact on the risk of alcoholic liver disease (ALD) than genetic predisposition.

5 Jul 2012

Strawberry extracts actively stimulate proteins that offer protection against cardiovascular disease

Strawberries, the traditional summer treat associated with Wimbledon could be serving up some unexpected health benefits.

4 Jul 2012

New research approach can help predict the 'tenability' of antibiotics

Research by Wageningen University, part of Wageningen UR, has shown that the development of bacteria with resistance against the antibiotic cefotaxime occurs more often and more predictably than was previously assumed. Bacterial populations were found to have many mutations that increase resistance and therefore have a negative effect on public health.

4 Jul 2012

The Jeffrey Epstein VI Foundation supports Genetic Initiative at CCFA

The Jeffrey Epstein VI Foundation, which actively supports science research, has given substantial support to the Crohn's and Colitis Foundation of America to continue its Genetic Initiative to find a cure for the diseases.

4 Jul 2012

UCLA Laboratory of Neuro Imaging to partner in new effort to combat Alzheimer's

Since 2004, UCLA's Laboratory of Neuro Imaging (LONI) has been responsible for receiving, organizing, archiving and disseminating the stream of data generated by the Alzheimer's Disease Neuroimaging Initiative (ADNI), an ambitious, worldwide effort by scientists to define the progression of Alzheimer's disease.

4 Jul 2012

Study examines how cells exploit gene sequences to cope with toxic stress

Toxic chemicals wreak havoc on cells, damaging DNA and other critical molecules. A new study from researchers at MIT and the University at Albany reveals how a molecular emergency-response system shifts the cell into damage-control mode and helps it survive such attacks by rapidly producing proteins that counteract the harm.

4 Jul 2012

Researchers identify mechanism responsible for inhibition of AMPK activity in the hypothalamus

In the complex chain of molecular events that underlie eating behaviors and body weight, the AMP-activated protein kinase (AMPK) enzyme has proven to be a critical link.

4 Jul 2012

Researcher discovers how West Nile virus breaks through the tough blood-brain barrier to CNS

Mosquitoes are buzzing once again, and with that comes the threat of West Nile virus. Tom Hobman, a researcher with the Li Ka Shing Institute of Virology in the Faculty of Medicine & Dentistry, is making every effort to put an end to this potentially serious infection.

4 Jul 2012

Medical Science News

Scientists discover new signalling pathway that controls both obesity and atherosclerosis

Scientists use antibody injections to rapidly reverse onset of Type I diabetes in mice

Reprogramming asthma-promoting immune cells diminishes airway damage and inflammation

Cancer Therapeutics announces validation and performance of CTx-294886 plus Avastin

Scientists discover constant cloud of potent inflammatory molecules surrounding the monocytes

Study shows cells from different Parkinson’s patients have unique drug responses

Eltrombopag can raise blood cell levels in some people with severe aplastic anemia

Neighboring non-cancer cells may contribute to drug resistance

Researchers use maternal blood sample to sequence genome of an unborn baby

Interfascicular matrix essential for tendon function

Lower pH reduces ability of ASL to kill bacteria in CF airways

Scientists identify causative link between oncometabolite and onset of AML

Alcoholic liver disease risk only ‘modestly’ affected by genetic factors

Strawberry extracts actively stimulate proteins that offer protection against cardiovascular disease

New research approach can help predict the 'tenability' of antibiotics

The Jeffrey Epstein VI Foundation supports Genetic Initiative at CCFA

UCLA Laboratory of Neuro Imaging to partner in new effort to combat Alzheimer's

Study examines how cells exploit gene sequences to cope with toxic stress

Researchers identify mechanism responsible for inhibition of AMPK activity in the hypothalamus

Researcher discovers how West Nile virus breaks through the tough blood-brain barrier to CNS

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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