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Agilent's microarrays used in landmark study on prenatal samples

Agilent Technologies Inc. today announced its microarrays were used in a landmark research study on prenatal samples. The three-year study was designed to evaluate the accuracy, efficacy and potential advantages of using microarray analysis as compared with conventional karyotyping. Agilent SurePrint CGH microarrays and analysis software were used for the majority sample cohort of 4,400 samples.

14 Feb 2012

People with Lynch syndrome face increased risks of breast and pancreatic cancers

A new prospective study of patients with Lynch syndrome - an inherited disorder of cancer susceptibility caused by mutations in specific DNA repair genes - provides the first strong evidence that people with Lynch syndrome face significantly increased risks of breast and pancreatic cancers.

14 Feb 2012

Compound makes imipenem 16 times more effective against antibiotic-resistant K. pneumoniae

North Carolina State University chemists have created a compound that makes existing antibiotics 16 times more effective against recently discovered antibiotic-resistant "superbugs."

14 Feb 2012

Researchers pinpoint source of Loeys-Dietz syndrome

A USC research team has pinpointed the source of a genetic disorder that causes life-threatening birth defects, which may allow doctors to quickly diagnose and better treat the disease.

14 Feb 2012

New software key for personalized cancer medicine

High-throughput DNA sequencing technologies are leading to a revolution in how clinicians diagnose and treat cancer. The molecular profiles of individual tumors are beginning to be used in the design of chemotherapeutic programs optimized for the treatment of individual patients.

14 Feb 2012

Pacific Biosciences releases major upgrade to PacBio RS system

Pacific Biosciences of California, Inc., provider of Single Molecule Real Time sequencing products, today announced it has released a major upgrade to its PacBio RS system, referred to as "C2", including new chemistry, enhanced SMRT Cells and upgraded software, which together provide customers with significant performance increases for DNA sequencing.

13 Feb 2012

Scientists test new 'therapeutic vaccine' against HIV on volunteers

Scientists from the Antwerp Institute of Tropical Medicine, Antwerp University Hospital and Antwerp University have tested a new 'therapeutic vaccine' against HIV on volunteers. The participants were so to say vaccinated with their own cells.

13 Feb 2012

Erasing neuronal memories may help control persistent pain

For some, the pain is so great that they can't even bear to have clothes touch their skin. For others, it means that every step is a deliberate and agonizing choice. Whether the pain is caused by arthritic joints, an injury to a nerve or a disease like fibromyalgia, research now suggests there are new solutions for those who suffer from chronic pain.

13 Feb 2012

Third patient dosed in Phase 1/2 SMD trial using RPE cells derived from hESCs

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today the dosing of third patient in its Phase 1/2 trial for Stargardt's macular dystrophy (SMD) using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (hESCs).

13 Feb 2012

Discovery of novel rearrangements and fusions supports role for NGS in treatment of cancer

Foundation Medicine, Inc., a molecular information company that brings comprehensive cancer gene analysis to routine clinical care, and Dana-Farber Cancer Institute today announced the Nature Medicine publication of results from their collaborative next-generation sequencing (NGS) study to assay cancer-relevant genes in 24 non-small cell lung cancer (NSCLC) and 40 colorectal cancer (CRC) cases.

13 Feb 2012

EU-funded 4DCellFate project to kick off today

Today European scientists are meeting to kick off the 4DCellFate project, funded by the European Commission under the FP7 program.

13 Feb 2012

Trevena commences TRV130 Phase I clinical trial for severe post-operative pain

Trevena, Inc., the leader in discovery and development of G-protein coupled receptor (GPCR) biased ligands, announced today the initiation of a Phase I clinical trial of TRV130, a novel candidate designed for the intravenous treatment of moderate-to-severe post-operative pain.

13 Feb 2012

Elevated levels of cell-free fetal DNA early in pregnancy do not predict preeclampsia

In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting -, in Dallas, Texas, researchers will report findings that indicate that elevated levels of cell-free DNA in the first trimester do not predict the subsequent development of preeclampsia.

13 Feb 2012

Study demonstrates dynamic genetic changes in ovarian cancers between diagnosis and recurrence

There is a need to analyze tumor specimens at the time of ovarian cancer recurrence, according to a new study published in Molecular Cancer Therapeutics.

13 Feb 2012

Early MSC transplantation can help repair neonatal brain damage

In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting -, in Dallas, Texas, researchers will report that early transplantation of human placenta-derived mesenchymal stem cells into the lateral ventricles of neonatal rats with birth-related brain damage is possible, and that the donor cells can survive and migrate in the recipient's brain.

13 Feb 2012

SAMHD1 protein cuts off raw material that HIV needs to create DNA and replicate

A protein that protects some of our immune cells from the most common and virulent form of HIV works by starving the virus of the molecular building blocks that it needs to replicate, according to research published online in Nature Immunology.

13 Feb 2012

Preterm birth interventions should be tailored for underlying risk factors and pathways

In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting -, in Dallas, Texas, researchers will report findings that indicate that preterm birth interventions should be tailored for underlying risk factors and pathways.

13 Feb 2012

Benefits of long-term Kineret therapy in people with NOMID

A new study shows that Kineret (anakinra), a medication approved for the treatment of rheumatoid arthritis, is effective in stopping the progression of organ damage in people with neonatal-onset multisystem inflammatory disease.

13 Feb 2012

New method can create scaffolds for tissue engineering applications

Researchers at Northwestern University have developed a new method for creating scaffolds for tissue engineering applications, providing an alternative that is more flexible and less time-intensive than current technology.

13 Feb 2012

Researchers discover a connection of peroxisomal protein import and receptor export

The group of Prof. Dr. Ralf Erdmann at the Ruhr-Universit-t Bochum discovered a connection of peroxisomal protein import and receptor export. In the Journal of Biological Chemistry, they disclosed that enzymes only get imported into certain cell organelles (peroxisomes) upon coupling of their import to the recycling of their transport protein.

13 Feb 2012

Medical Science News

Agilent's microarrays used in landmark study on prenatal samples

People with Lynch syndrome face increased risks of breast and pancreatic cancers

Compound makes imipenem 16 times more effective against antibiotic-resistant K. pneumoniae

Researchers pinpoint source of Loeys-Dietz syndrome

New software key for personalized cancer medicine

Pacific Biosciences releases major upgrade to PacBio RS system

Scientists test new 'therapeutic vaccine' against HIV on volunteers

Erasing neuronal memories may help control persistent pain

Third patient dosed in Phase 1/2 SMD trial using RPE cells derived from hESCs

Discovery of novel rearrangements and fusions supports role for NGS in treatment of cancer

EU-funded 4DCellFate project to kick off today

Trevena commences TRV130 Phase I clinical trial for severe post-operative pain

Elevated levels of cell-free fetal DNA early in pregnancy do not predict preeclampsia

Study demonstrates dynamic genetic changes in ovarian cancers between diagnosis and recurrence

Early MSC transplantation can help repair neonatal brain damage

SAMHD1 protein cuts off raw material that HIV needs to create DNA and replicate

Preterm birth interventions should be tailored for underlying risk factors and pathways

Benefits of long-term Kineret therapy in people with NOMID

New method can create scaffolds for tissue engineering applications

Researchers discover a connection of peroxisomal protein import and receptor export

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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