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Study on how Hedgehog signal defines cell-cell interaction receives $747,000 grant

While many researchers believe that the Hedgehog (Hh) signaling pathway, which transmits information to embryonic cells for proper development and is important for regeneration, may actually regulate cell-cell adhesion and segregation - there isn't any evidence.

16 Mar 2013

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies.

16 Mar 2013

Abiraterone's anti-androgenic properties may stop tumor growth of CRPC, says prize-winning Dutch study

As part of an EU-supported IMI-PREDECT consortium, a Dutch study showed that anti-androgenic properties of the drug abiraterone may provide an additional mechanism of action in blocking tumour growth of castration resistant prostate cancer (CRPC).

16 Mar 2013

Genetic score based on PCa risk-associated SNPs predicts prostate biopsy outcomes: Study

A genetic score based on PCa risk-associated single nucleotide polymorphisms is an independent predictor of prostate biopsy outcomes, suggest the results of a new study conducted by a group from the Department of Urology Huashan Hospital, Fudan University in Shanghai, China.

16 Mar 2013

Researchers identifiy elusive anti-cancer property of vitamin E

Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find. Many animal studies have suggested that vitamin E could prevent cancer, but human clinical trials following up on those findings have not shown the same benefits.

16 Mar 2013

Elevation of stress steroids in the brain speeds up Alzheimer disease

Why does chronic stress lead to increased risk for dementia? The answer may lie in the elevation of stress steroids that is seen in the brain during stress, Sara K. Bengtsson suggests in the thesis she is defending at Umeå University in Sweden on March 22nd.

16 Mar 2013

Discovery could lead to new target for treatment of cocaine addiction

Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug.

16 Mar 2013

Research: Decreased levels of vitamin D may influence smokers to develop tobacco-related cancer

New research appearing online today in Clinical Chemistry, the journal of AACC, shows that decreased levels of vitamin D may predispose smokers to developing tobacco-related cancer.

16 Mar 2013

Historical review provides lessons for control of plague

Today archaeologists unearthed a 'Black Death' grave in London, containing more than a dozen skeletons of people suspected to have died from the plague. The victims are thought to have died during the 14th century and archaeologists anticipate finding many more as they excavate the site.

16 Mar 2013

Alzheimer's research demonstrates cell-to-cell transmission of neurodegenerative proteins

Injecting synthetic tau fibrils into animal models induces Alzheimer's-like tau tangles and imitates the spread of tau pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania being presented at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013.

16 Mar 2013

MBL study of dragonfly prey detection wins 2012 Cozzarelli Prize for scientific excellence and originality

Paloma T. Gonzalez-Bellido, a postdoctoral scientist at the Marine Biological Laboratory and her colleagues have been awarded a 2012 Cozzarelli Prize by the editorial board of the Proceedings of the National Academy of Sciences.

16 Mar 2013

Scientists develop pig brain model to study human brain development

A mutual curiosity about patterns of growth and development in pig brains has brought two University of Illinois research groups together. Animal scientists Rod Johnson and Ryan Dilger have developed a model of the pig brain that they plan to use to answer important questions about human brain development.

16 Mar 2013

Research shows changes in mouse coat color were the result of nine mutations within a single gene

For deer mice living in the Nebraska Sandhills, color can literally be the difference between life and death. When they first colonized the region, the dark-coated mice stood out starkly against the light-colored, sandy soil, making them easy prey for predators.

15 Mar 2013

Previously unknown cell discovered in the urethra of mice

A recent study conducted by a group of German scientists revealed the presence of a previously unknown cell in the urethra of mice. These chemosensory cholinergic brush cells are in close contact to sensory neurons that express cholinergic receptors.

15 Mar 2013

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific for proteins on the outside of the virus, specifically the hemagglutinin protein.

15 Mar 2013

Brown fat cells protective against obesity and diabetes

Brown fat is a hot topic, pardon the pun. Brown fats cells, as opposed to white fat cells, make heat for the body, and are thought to have evolved to help mammals cope with the cold. But, their role in generating warmth might also be applied to coping with obesity and diabetes.

15 Mar 2013

New hunt for intrinsic mechanism linked to schizophrenia

Since the 1960s, psychiatrists have been hunting for substances made by the body that might accumulate in abnormally high levels to produce the symptoms associated with schizophrenia. In particular, there was a search for chemicals that might be related to the hallucinogens phencyclidine (PCP) or lysergic acid diethylamide (LSD), which could explain the emergence of psychotic symptoms in schizophrenia.

15 Mar 2013

Researchers show inhibiting brain's filter can boost performance for tasks

The brain's prefrontal cortex is thought to be the seat of cognitive control, working as a kind of filter that keeps irrelevant thoughts, perceptions and memories from interfering with a task at hand.

15 Mar 2013

Researchers identify enzymes that activate coronavirus for infection

Scientists all over the world are on a quest for an antidote since the first patient died from the new coronavirus in summer 2012. Infection Researchers from the German Primate Center have now identified enzymes that activate the virus for infection.

15 Mar 2013

Article explores benefits of innovative programs for personalized health care

Two innovative programs designed to improve the availability of emerging medical technologies that can help patients receive more effective, efficient and personalized health care are advanced in a commentary written by a team of scientists and policy experts, including seven from Arizona State University, and published today in Science Translational Medicine.

15 Mar 2013

Medical Science News

Study on how Hedgehog signal defines cell-cell interaction receives $747,000 grant

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Abiraterone's anti-androgenic properties may stop tumor growth of CRPC, says prize-winning Dutch study

Genetic score based on PCa risk-associated SNPs predicts prostate biopsy outcomes: Study

Researchers identifiy elusive anti-cancer property of vitamin E

Elevation of stress steroids in the brain speeds up Alzheimer disease

Discovery could lead to new target for treatment of cocaine addiction

Research: Decreased levels of vitamin D may influence smokers to develop tobacco-related cancer

Historical review provides lessons for control of plague

Alzheimer's research demonstrates cell-to-cell transmission of neurodegenerative proteins

MBL study of dragonfly prey detection wins 2012 Cozzarelli Prize for scientific excellence and originality

Scientists develop pig brain model to study human brain development

Research shows changes in mouse coat color were the result of nine mutations within a single gene

Previously unknown cell discovered in the urethra of mice

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Brown fat cells protective against obesity and diabetes

New hunt for intrinsic mechanism linked to schizophrenia

Researchers show inhibiting brain's filter can boost performance for tasks

Researchers identify enzymes that activate coronavirus for infection

Article explores benefits of innovative programs for personalized health care

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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