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UC Riverside to study molecular basis of hormonal regulation of mosquito reproduction

Female mosquitoes require energy for their egg development, which they acquire from vertebrate blood. But by sucking on blood, they become vectors of numerous disease pathogens of human and domestic animals. If the mechanisms that govern their egg production are better understood, novel approaches to controlling the reproduction and population of mosquitoes can be devised.

23 Mar 2012

Immediate skull reconstruction aggravates brain damage in TBI model

Immediate skull reconstruction following trauma that penetrates or creates an indentation in the skull can aggravate brain damage inflicted by the initial injury, a study by a University of South Florida research team reports.

23 Mar 2012

Scripps scientists generate synthetic memory trace

Scripps Research Institute scientists and their colleagues have successfully harnessed neurons in mouse brains, allowing them to at least partially control a specific memory. Though just an initial step, the researchers hope such work will eventually lead to better understanding of how memories form in the brain, and possibly even to ways to weaken harmful thoughts for those with conditions such as schizophrenia and post traumatic stress disorder.

23 Mar 2012

Prenatal PAH exposure can lead to behavioral problems in children

Mothers' exposure during pregnancy to a class of air pollutants called polycyclic aromatic hydrocarbons (PAH) can lead to behavioral problems in their children.

23 Mar 2012

TAS2R38 and CD36 gene may play a role in fat perception

While high-fat foods are thought to be of universal appeal, there is actually a lot of variation in the extent to which people like and consume fat. A new study in the March issue of the Journal of Food Science, published by the Institute of Food Technologists, reported that two specific genes, may play a role in some people's ability to taste and enjoy dietary fat.

23 Mar 2012

Researchers identify corin enzyme linked with pre-eclampsia

Researchers have identified an enzyme linked to pregnancy-induced hypertension - also known as pre-eclampsia - a pregnancy complication characterized by high blood pressure and swelling due to fluid retention. The findings could be used to better screen for - and treat - this condition.

23 Mar 2012

Scientists artificially derive brain stem cells from connective tissue of mice

These stem cells can reproduce and be converted into various types of brain cells. To date, only reprogramming in brain cells that were already fully developed or which had only a limited ability to divide was possible. The new reprogramming method presented by the Bonn scientists and submitted for publication in July 2011 now enables derivation of brain stem cells that are still immature and able to undergo practically unlimited division to be extracted from conventional body cells.

23 Mar 2012

Blocking PFKFB4 enzyme could prevent growth of prostate cancer cells

Cancer Research UK scientists have discovered how blocking a key enzyme, which helps convert glucose into energy, could provide a new way to kill prostate cancer cells, according to a study published in the journal Cancer Discovery.

23 Mar 2012

tAI could predict sensitivity to chemotherapy in patients with triple-negative breast cancer

Scientists have uncovered a marker of DNA damage that could predict who will respond to platinum-based chemotherapy drugs like cisplatin or carboplatin.

23 Mar 2012

Study provides important clue in type 1 diabetes

In type 1 diabetes (T1D), pancreatic beta cells die from a misguided autoimmune attack, but how and why that happens is still unclear. Now, JDRF-funded scientists from the Indiana University School of Medicine have found that a specific type of cellular stress takes place in pancreatic beta cells before the onset of T1D, and that this stress response in the beta cell may in fact help ignite the autoimmune attack.

23 Mar 2012

PFKFB4 gene leads to excessive growth of prostate cancer cells

Cancer cell metabolism may present a new target for therapy as scientists have uncovered a possible gene that leads to greater growth of prostate cancer cells.

23 Mar 2012

Verapamil drug may reverse diabetes-related death of pancreatic beta cells

A common high-blood-pressure medication appears to reverse the diabetes-related death of pancreatic beta cells, according to a University of Alabama at Birmingham study published today in the journal Diabetes.

23 Mar 2012

Study identifies abnormal brain gene expression patterns in autism

A study led by Eric Courchesne, PhD, director of the Autism Center of Excellence at the University of California, San Diego School of Medicine has, for the first time, identified in young autism patients genetic mechanisms involved in abnormal early brain development and overgrowth that occurs in the disorder. The findings suggest novel genetic and molecular targets that could lead to discoveries of new prevention strategies and treatment for the disorder.

23 Mar 2012

WCI technique uses MRS to detect oncometabolites

Researchers at Winship Cancer Institute have developed a technique for detecting an "oncometabolite", a chemical produced by some brain tumors' warped metabolism, via non-invasive imaging.

23 Mar 2012

Towards a more comprehensive view of brain-hand relationship

Research at Arizona State University and Columbia University to better understand the intricate sensory and cognitive connections between the brain and the hands has won support from the National Science Foundation. New discoveries about such connections could benefit people with neurological disorders such as Parkinson's disease and cerebral palsy, and those who need prosthetic hands.

22 Mar 2012

Biobanks should set rules for overall process of recognizing IFs and IRRs

Bioethicists at the Johns Hopkins Berman Institute of Bioethics are co-authors on a consensus article placing "significant responsibility" on biobanks to report individual research results (IRRs) and incidental findings (IFs) to the contributors of genetic material.

22 Mar 2012

A rare forum on stem cell biology, engineering and clinical translation

On March 23, during the 41st Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 36th Annual Meeting of the Canadian Association for Dental Research, a symposium titled "TMJ: Stem Cell Biology and Engineering toward Clinical Translation" will provide a rare forum for multidisciplinary discussion of the biology, engineering and clinical translation of fundamental discoveries towards novel clinical therapy.

22 Mar 2012

Reading Arabic is more challenging to the brain

Readers whose mother tongue is Arabic have more challenges reading in Arabic than native Hebrew or English speakers have reading their native languages, because the two halves of the brain divide the labor differently when the brain processes Arabic than when it processes Hebrew or English.

22 Mar 2012

Study uses Veridex CellSearch technology to capture CECs in MI patients

Veridex, LLC today announced the publication of a new, investigational study published this week in Science Translational Medicine that lays the foundation for research that may potentially result in a blood test to determine imminent risk of heart attack within high-risk populations.

22 Mar 2012

Study identifies ROS in the gaseous phase of cigarette smoke

A team of researchers led by A. K. Rajasekaran, PhD, Director of the Nemours Center for Childhood Cancer Research, has shown that a key protein involved in cell function and regulation is stopped by a substance present in cigarette smoke.

22 Mar 2012