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PNAS: Ras proteins bring tension to the phosphate chain

Proteins accelerate certain chemical reactions in cells by several orders of magnitude. The molecular mechanism by which the Ras protein accelerates the cleavage of the molecule GTP and thus slows cell growth is described by biophysicists at the Ruhr-Universit-t Bochum led by Prof. Dr. Klaus Gerwert in the Online Early Edition of the journal PNAS.

20 Sep 2012

NIH announces multiple awards to UCLA Center for Autism Research and Treatment

The National Institutes of Health, recognizing UCLA's preeminence in both research and clinical care for children with autism, has announced multiple awards to the university as part of the agency's Autism Centers of Excellence (ACE) research program.

20 Sep 2012

UK scientists make breakthrough in new method of brain tumour diagnosis

UK scientists have made a breakthrough in a new method of brain tumour diagnosis, offering hope to tens of thousands of people.

20 Sep 2012

Molecular disruptions in granule cells cause epileptic seizures in mice

Scientists have discovered the first direct evidence that a biological mechanism long suspected in epilepsy is capable of triggering brain seizures – opening the door for studies to seek improved treatments or even preventative therapies.

20 Sep 2012

Adults with autism have unreliable neural sensory responses to visual, auditory and touch

Autistic adults have unreliable neural sensory responses to visual, auditory, and touch stimuli, according to research published in the journal Neuron. This poor response reliability, the study's authors conclude, appears to be a fundamental neural characteristic of autism.

20 Sep 2012

Tel Aviv University researcher discovers homing device that draws cancer

The process of metastasis, by which cancer cells travel from a tumor site and proliferate at other sites in the body, is a serious threat to cancer patients. According to the National Cancer Institute, most recurrences of cancer are metastases rather than "new" cancers.

20 Sep 2012

Thermo Fisher Scientific announces opening of Molecular Biology Center of Excellence in Lithuania

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the official opening of its Molecular Biology Center of Excellence in Vilnius, Lithuania.

From Thermo Fisher Scientific Inc. 20 Sep 2012

PCA inhibits multiple pathways involved in development of diabetic nephropathy

Diabetic nephropathy is one of the most serious complications related to diabetes, often leading to end-stage kidney disease. Purple corn grown in Peru and Chile is a relative of blue corn, which is readily available in the U.S.

20 Sep 2012

RRM2 may be a facilitating factor in colorectal cancer and UV-induced DNA damage repair

Colorectal cancer (CRC) is the leading cause of cancer-related death worldwide. In addition, the incidence and mortality rates of colorectal cancer are on the rise. Recently, metabolic genes have received increasing and specific attention due to their potential role in carcinogenesis.

20 Sep 2012

Scientists identify unique molecular signature in iPSCs that show promise in regenerative medicine

Salk scientists have identified a unique molecular signature in induced pluripotent stem cells (iPSCs), "reprogrammed" cells that show great promise in regenerative medicine thanks to their ability to generate a range of body tissues.

20 Sep 2012

Endothelial colony-forming cells show promise against inflammatory bowel disease

New research shows that a special population of stem cells found in cord blood has the innate ability to migrate to the intestine and contribute to the cell population there, suggesting the cells' potential to treat inflammatory bowel disease (IBD).

20 Sep 2012

Study uncovers why some HIV-positive people take long time to progress to full-blown AIDS

One of the big mysteries of AIDS is why some HIV-positive people take more than a decade to progress to full-blown AIDS, if they progress at all.

20 Sep 2012

Obese adults with excess visceral fat, biomarkers of insulin resistance more likely to develop diabetes

Obese adults with excess visceral fat (fat located inside the abdominal cavity, around the body's internal organs) and biomarkers of insulin resistance had an associated increased risk for the development of type 2 diabetes mellitus, while obese individuals with higher amounts of total body fat and subcutaneous fat (underneath the skin) did not have this increased risk, according to a study in the September 19 issue of JAMA, and theme issue on obesity.

20 Sep 2012

Complete story behind connection between XMRV virus and prostate cancer

A once-promising discovery linking prostate cancer to an obscure retrovirus derived from mice was the result of an inadvertent laboratory contamination, a forensic analysis of tissue samples and lab experiments - some dating back nearly a decade - has confirmed.

20 Sep 2012

APR-246 can restore function of defective p53 and activate apoptosis in cancer cells

The p53 gene plays a key role in the prevention of cancer, by blocking cell growth and triggering programmed cell death or apoptosis. If, however, p53 has mutated and become defective, the cancer cells can acquire the ability to evade apoptosis and become more resistant to therapy.

20 Sep 2012

Study finds links between antibodies for multiple oral bacteria and risk of pancreatic cancer

A new study finds significant associations between antibodies for multiple oral bacteria and the risk of pancreatic cancer, adding support for the emerging idea that the ostensibly distant medical conditions are related.

19 Sep 2012

Music underlies the ability to acquire language

Contrary to the prevailing theories that music and language are cognitively separate or that music is a byproduct of language, theorists at Rice University's Shepherd School of Music and the University of Maryland, College Park (UMCP) advocate that music underlies the ability to acquire language.

19 Sep 2012

Hereditary blood disorder found in South-East Asia, South-West Pacific could offer clues for malaria vaccine

"A team of international scientists has found that a type of hereditary disorder in some communities in South-East Asia and the South-West Pacific protects its sufferers from malaria, a finding that could drive future vaccine design," SciDev.Net reports.

19 Sep 2012

Scientists discover bone abnormalities in rats undergoing chronic lack of sleep

Scientists at the Medical College of Wisconsin, in a team led by Carol Everson, Ph.D., professor of neurology, cell biology, neurobiology and anatomy, have discovered abnormalities in bone and bone marrow in rats undergoing chronic lack of sleep. They discovered abnormalities in serum markers of bone metabolism in sleep-deprived rats, which led them to conduct direct measurements of bone parameters; this time in rats experiencing recurrent sleep restriction during a large portion of their young adulthood.

19 Sep 2012

Researchers identify 21 proteins that specifically bind to ataxin-1

Misfolded proteins can cause various neurodegenerative diseases such as spinocerebellar ataxias (SCAs) or Huntington's disease, which are characterized by a progressive loss of neurons in the brain. Researchers of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, together with their colleagues of the Universit- Paris Diderot, Paris, France, have now identified 21 proteins that specifically bind to a protein called ataxin-1.

19 Sep 2012

Medical Science News

PNAS: Ras proteins bring tension to the phosphate chain

NIH announces multiple awards to UCLA Center for Autism Research and Treatment

UK scientists make breakthrough in new method of brain tumour diagnosis

Molecular disruptions in granule cells cause epileptic seizures in mice

Adults with autism have unreliable neural sensory responses to visual, auditory and touch

Tel Aviv University researcher discovers homing device that draws cancer

Thermo Fisher Scientific announces opening of Molecular Biology Center of Excellence in Lithuania

PCA inhibits multiple pathways involved in development of diabetic nephropathy

RRM2 may be a facilitating factor in colorectal cancer and UV-induced DNA damage repair

Scientists identify unique molecular signature in iPSCs that show promise in regenerative medicine

Endothelial colony-forming cells show promise against inflammatory bowel disease

Study uncovers why some HIV-positive people take long time to progress to full-blown AIDS

Obese adults with excess visceral fat, biomarkers of insulin resistance more likely to develop diabetes

Complete story behind connection between XMRV virus and prostate cancer

APR-246 can restore function of defective p53 and activate apoptosis in cancer cells

Study finds links between antibodies for multiple oral bacteria and risk of pancreatic cancer

Music underlies the ability to acquire language

Hereditary blood disorder found in South-East Asia, South-West Pacific could offer clues for malaria vaccine

Scientists discover bone abnormalities in rats undergoing chronic lack of sleep

Researchers identify 21 proteins that specifically bind to ataxin-1

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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