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New protein in the fruit fly eye may shed light on neurodegenerative diseases

Researchers at the University of Wisconsin-Madison and collaborators have discovered a powerful new protein in the eye of the fruit fly that may shed light on blinding diseases and other sensory problems in humans.

18 Nov 2011

Researchers discover new class of antimalarial compounds

Researchers have discovered a group of chemical compounds that might one day be developed into drugs that can treat malaria infection in both the liver and the bloodstream.

18 Nov 2011

Dendrimers can capture circulating tumor cells in blood by biomimicry

The removal of rare tumor cells circulating in the blood might be possible with the use of biomolecules bound to dendrimers, highly branched synthetic polymers, which could efficiently sift and capture the diseased cells, according to new research at the University of Illinois at Chicago.

18 Nov 2011

Simple roundworm may serve as ideal skin wound healing lab model

The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body's response to healing skin wounds, a serious problem in diabetics and the elderly.

18 Nov 2011

Blocking CaM kinase may help prevent cardiac rupture

For people who initially survive a heart attack, a significant cause of death in the next few days is cardiac rupture -- literally, bursting of the heart wall. A new study by University of Iowa researchers pinpoints a single protein as the key player in the biochemical cascade that leads to cardiac rupture.

18 Nov 2011

AHA honors Gladstone scientist with Katz award for cardiovascular research

Li Qian, PhD, has won the Louis N. and Arnold M. Katz Basic Science Research Prize for Young Investigators from the American Heart Association (AHA), marking the first time in the prestigious award's history that a Gladstone Institutes researcher has been the recipient.

18 Nov 2011

World's fastest program to examine interactions between molecules

Creating new, improved pharmaceuticals is sometimes very similar to cracking the code of a combination lock. If you have the wrong numbers, the lock won't open. Even worse, you don't know if your numbers are close to the actual code or way off the mark. The only solution is to simply guess a new combination and try again.

18 Nov 2011

First study to describe transporter system that bacteria use to ensure their survival

Bacteria responsible for middle ear infections, pink eye and sinusitis protect themselves from further immune attack by transporting molecules meant to destroy them away from their inner membrane target, according to a study from Nationwide Children's Hospital.

18 Nov 2011

Study demonstrates how DISC1 variants affect brain development

Significant progress has been made in understanding the genetic risk factors underlying psychiatric disease. Recent studies have identified common genetic mutations conferring modest risk and rare variants comprising significant risk. One example of a rare cause of psychiatric disorders is the Disrupted in Schizophrenia-1 (DISC1) gene, first identified in a large Scottish pedigree displaying schizophrenia, bipolar disorder and depression.

18 Nov 2011

MU scientist examines how enzymes influence immune system's ability to fight infection

The influenza virus remains a worldwide threat to humans, causing an average of 36,000 deaths and 200,000 hospitalizations each year in the United States alone. As health care professionals prepare for another flu season, a University of Missouri scientist is studying how two enzymes could be used to stop the virus in its tracks.

18 Nov 2011

InDevR introduces ampliPHOX system for microbiological analysis

InDevR, a Boulder-based biotechnology company that develops advanced life science instrumentation and assays for analysis of viruses and other microorganisms, announced today the launch revolutionary new technology for microbiological analysis.

18 Nov 2011

Researchers use baker's yeast to gain insight into chromosome separation process

Researchers at the Stowers Institute for Medical Research used, ironically enough, the single-celled organism Saccharomyces cerevisiae -- commonly known as baker's yeast -- to gain new insight into the process by which chromosomes are physically segregated during cell division.

18 Nov 2011

Chloroquine-chemotherapy combination holds potential for metastatic breast cancer treatment

An anti-malaria drug used for more than 60 years is now being studied for use in breast cancer patients whose disease has not responded to traditional chemotherapy treatment.

18 Nov 2011

Scientists discover family of chemical compounds that could prevent malaria

A international team led by scientists from the Genomics Institute of the Novartis Research Foundation (GNF) and The Scripps Research Institute has discovered a family of chemical compounds that could lead to a new generation of antimalarial drugs capable of not only alleviating symptoms but also preventing the deadly disease.

17 Nov 2011