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Researchers discover unexpected mode of action for vaccine adjuvant alum

The teams of Doctor Christophe Desmet and Professor Fabrice Bureau, of the Laboratory of Cellular and Molecular Physiology within the University of Liège's GIGA-Research centre, and of Professor Ken Ishii at the University of Osaka in Japan have just discovered an unexpected mode of action for the vaccine adjuvant alum.

18 Jul 2011

Landmark study may help prevent permanent brain injury in fighters

The Cleveland Clinic Lou Ruvo Center for Brain Health has launched a landmark study with professional fighters that will help determine whether magnetic resonance imaging (MRI) of the brain, along with other tests, can detect subtle changes in brain health that correlate with impaired thinking and functioning.

18 Jul 2011

Viral toxin causes release of serotonin leading to vomiting

It is well known that viruses like rotavirus and norovirus are behind the majority of stomach infections. But it was unclear how vomiting developed, and the treatments available were oral fluid replacement and intravenous drips to prevent dehydration of the body.

18 Jul 2011

Scientists use two methods to manipulate disease-causing mutations in stem cells

Using two distinct methods, Whitehead Institute researchers have successfully and consistently manipulated targeted genes in both human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells.

16 Jul 2011

Grape seed polyphenols may help prevent Alzheimer's disease

Researchers at Mount Sinai School of Medicine have found that grape seed polyphenols—a natural antioxidant—may help prevent the development or delay the progression of Alzheimer's disease.

16 Jul 2011

Autism Speaks honors Scripps Research scientist with Weatherstone Fellowship

Autism Speaks, the nation's largest autism science and advocacy group, has awarded a two-year Dennis Weatherstone Pre-Doctoral Fellowship to Kristopher Nazor of The Scripps Research Institute.

16 Jul 2011

New study confirms key risk factors for heavy drinking among adolescents

A low level of response (LR) to alcohol is one of several genetically influenced characteristics that may increase an individual's risk for heavy drinking and alcohol problems. A new study has confirmed key elements of a LR-based model of risk through examination of a large sample of adolescent boys and girls in the United Kingdom, moving beyond smaller U.S.-based samples and to younger subjects.

16 Jul 2011

Propranolol can block brain from retrieving cocaine-associated memories

New discoveries by researchers at the University of Wisconsin-Milwaukee (UWM) offer potential for development of a first-ever pharmacological treatment for cocaine addiction.

16 Jul 2011

Research: 17 genetic mutations linked to colon cancer formation

Researchers at UT Southwestern Medical Center say there are at least 70 genetic mutations involved in the formation of colon cancer, far more than scientists previously thought.

16 Jul 2011

USC researcher maps human brain that generates empathy

According to a new study from USC, even failing to possess a full complement of limbs will not stop your brain from understanding what it is like for someone else to experience pain in one of them. It may, however, change the way your brain does so.

16 Jul 2011

Retinal cells require vitamin C to function properly

Nerve cells in the eye require vitamin C in order to function properly - a surprising discovery that may mean vitamin C is required elsewhere in the brain for its proper functioning, according to a study by scientists at Oregon Health & Science University recently published in the Journal of Neuroscience.

16 Jul 2011

Female teens more vulnerable to negative effects of binge drinking

Binge or "heavy episodic" drinking is prevalent during adolescence, raising concerns about alcohol's effects on crucial neuromaturational processes during this developmental period.

16 Jul 2011

New DNA sequencer will provide deeper insight into gene regulation

The Berlin Institute for Medical Systems Biology (BIMSB) of the Max Delbr-ck Center for Molecular Medicine (MDC) in Berlin, Germany, will be the first academic research institution in Continental Europe to acquire a novel DNA sequencer enabling the sequencing of single DNA molecules in real time.

16 Jul 2011

Researchers discover new gene mutation associated with Parkinson's

Researchers have discovered a new gene mutation they say causes Parkinson's disease. The mutation was identified in a large Swiss family with Parkinson's disease, using advanced DNA sequencing technology.

16 Jul 2011

Stored red blood cells lose ability to release key anti-adhesive molecule

Donated red blood cells lose a key feature that diminishes their lifesaving power the longer they have been stored, according to researchers at Duke University Medical Center.

16 Jul 2011

Researchers discover new gene linked to intellectual disability

A gene linked to intellectual disability was found in a study involving the Centre for Addiction and Mental Health (CAMH) - a discovery that was greatly accelerated by international collaboration and new genetic sequencing technology, which is now being used at CAMH.

15 Jul 2011

Implantable fuel cells may obtain energy from blood sugar and oxygen

Implants that obtain their energy from blood sugar and oxygen: Dr. Sven Kerzenmacher at the Department of Microsystems Engineering (IMTEK) of the University of Freiburg is researching the development of biological fuel cells with the goal of finding an inexhaustible source of power in the human body. He has been awarded the 2011 FAM Research Prize for his dissertation by the Forum for Applied Microsystems Technology (FAM).

15 Jul 2011

Genome Research publishes studies utilizing emerging Collaborative Cross mouse strains

The Collaborative Cross represents a large collection of new inbred mouse strains created by the mouse genetics community aimed at revolutionizing the study of complex genetic traits and diseases. Derived from classical inbred strains and wild-derived strains, the CC captures nearly 90% of known genetic variation in laboratory mice, far surpassing more commonly used inbred strains.

15 Jul 2011

Methods and trends in evaluation of cancer risk

The development of almost all cancer is influenced by environmental factors, argues Dr Günter Obe and co-editors in their new title Cancer Risk Evaluation: Methods and Trends. However, while some environmental factors, such as smoking or ionizing radiation, puts the vast majority of humans at risk regardless of their genetic background, many other risk factors such as hazardous working conditions, increase the cancer risk for smaller groups of the population and are often dependent on additional factors as well as an individual's genetics.

15 Jul 2011

Scientists analyze structural changes in calcium channels caused by Timothy-mutation

The human genome encodes 243 voltage-gated ion channels. Mutations in calcium channels can cause severe inherited diseases such as migraine, night blindness, autism spectrum disorders and Timothy syndrome, which leads to severe cardiovascular disorders.

15 Jul 2011