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Elite controllers' T cells resist HIV-1 infection by selective upregulation of protein p21

In the years since the AIDS epidemic began, it has become clear that there is substantial variation in the way that individuals respond to HIV infection. Although most progress quickly from initial infection to immunodeficiency, a small subset survive for long periods without developing symptoms.

16 Mar 2011

NIH awards TriLink $100,000 Phase I SBIR Grant to develop Hot Start approach for Ligase Chain Reaction

TriLink BioTechnologies, Inc. was recently awarded a Phase I SBIR Grant of approximately $100,000 by the National Institutes of Health to develop a Hot Start approach for Ligase Chain Reaction (LCR). Hot Start LCR will employ chemically modified ligation components containing thermolabile protecting groups to eliminate common performance problems seen in LCR, such as false-positive signals and non-specificity.

16 Mar 2011

Experimental vaccine against human norovirus generates strong, safe immune response in mice

Scientists have shown that an experimental vaccine against the human norovirus - the bug behind about 90 percent of highly contagious nonbacterial illnesses that cause diarrhea and vomiting - can generate a strong immune response in mice without appearing to cause the animals any harm.

16 Mar 2011

Genomatix launches service model for NGS data analysis

The growing amount of data created by today's high throughput DNA sequencing technology presents a major challenge to scientists around the globe. How to handle the staggering amount of data, and, more importantly, how to answer the biological questions that initiated the experiment?

16 Mar 2011

Backscattering interferometry can precisely measure membrane protein interactions

A new laser technique has demonstrated that it can measure the interactions between proteins tangled in a cell's membrane and a variety of other biological molecules. These extremely difficult measurements can aid the process of drug discovery.

16 Mar 2011

Malaria drug shrinks, slows resistant pancreatic tumors

Dana-Farber Cancer Institute scientists report they have shrunk or slowed the growth of notoriously resistant pancreatic tumors in mice, using a drug routinely prescribed for malaria and rheumatoid arthritis.

16 Mar 2011

Protein folding may aid in developing new therapies for brain diseases

Misfold an origami swan and the worst that happens is you wind up with an ugly paper duckling. Misfold one of the vital proteins in your body - each of which must be folded in a particular way to perform its function - and the result can be a debilitating neurodegenerative disease such as Alzheimer's or Huntington's.

16 Mar 2011

Insight into Lyme disease

Researchers recently developed novel diagnostic tools able to distinguish between the various strains of bacteria responsible for causing Lyme disease. For more than a decade, only one strain of B. burgdorferi had been sequenced, and although that helped research efforts, it was not sufficient to understand the relationship between geographic variations in strains and disease characteristics.

16 Mar 2011

Anti-cancer drug loaded microcarriers successfully guided to targeted area in the liver

Soon, drug delivery that precisely targets cancerous cells without exposing the healthy surrounding tissue to the medication's toxic effects will no longer be an oncologist's dream but a medical reality, thanks to the work of Professor Sylvain Martel, Director of the Nanorobotics Laboratory at Polytechnique Montr-al.

16 Mar 2011

Manchester research offers hope for congenital hyperinsulinism treatment

University of Manchester scientists have led an international team to discover new treatments for a rare and potentially lethal childhood disease that is the clinical opposite of diabetes mellitus.

16 Mar 2011

Researchers identify genetic cause of magnesium deficiency

Researchers and scientists of the Charité - Universitätsmedizin Berlin, in cooperation with the Max Delbrück Center for Molecular Medicine, and colleagues from the Netherlands, Belgium, Switzerland and the Czech Republic have succeeded in identifying a genetic cause of magnesium deficiency.

16 Mar 2011

BRAF gene defect leads to pilocytic astrocytoma in children

Pilocytic astrocytoma, the most common brain tumor in children, is usually slow-growing and benign. However, surgeons often cannot completely remove the diffusely growing tumor.

16 Mar 2011

Researchers discover molecular switch for insulin secretion

Johns Hopkins researchers believe they have uncovered the molecular switch for the secretion of insulin — the hormone that regulates blood sugar — providing for the first time an explanation of this process.

16 Mar 2011

March of Dimes to honor fragile X syndrome researcher with Lifetime Achievement award

A world-renowned fragile X syndrome researcher, who was the first to identify the long-sought genetic abnormality responsible for this disorder, will be honored by the March of Dimes.

16 Mar 2011

Study investigates physiological changes within brain due to Prozac treatment

Selective serotonin reuptake inhibitors (SSRI) such as Prozac are regularly used to treat severe anxiety and depression. They work by immediately increasing the amount of serotonin in the brain and by causing long term changes in brain function. However it can take weeks of treatment before a patient feels any effect and both beneficial effects and side effects can persist after treatment is stopped.

16 Mar 2011

Study underscores need for monitoring vitamin D levels in all cirrhosis patients

Vitamin D deficiency is a well reported complication in chronic cholestatic liver disease such as primary biliary cirrhosis. While the prevalence and treatment of this deficiency has been addressed in many articles over the last decades, little is known of the vitamin D status in alcoholic liver cirrhosis.

16 Mar 2011

Enzo Life Sciences introduces ELISA system to detect SMN protein

Enzo Biochem, Inc. and the Spinal Muscular Atrophy Foundation today announced that Enzo's wholly owned subsidiary, Enzo Life Sciences Inc., has launched a unique immunoassay system which can be used for the identification and detection of Survival Motor Neuron protein.

16 Mar 2011

XTIO2 presents XTI 360 ANTI-GERM SYSTEM to 83rd Academy Award-nominees

XTIO2 INC. (XTI) presented the 83rd Academy® Award-nominees with the XTI ANTI-GERM / ANTI-VOC / ANTI-ALLERGY SYSTEM, consisting of XTI 360™ Nanocoating and XTI™ Nano-Facemask. It is the world's most effective preventive measure and the best defense against germs transmitted via air and contact surfaces.

15 Mar 2011

Ingenuity announces new features to support RNA-Seq workflows, microRNA research in IPA

Ingenuity Systems, a leading provider of information and analytics solutions for life science researchers, today announced new features to support RNA-Sequencing workflows and microRNA research in IPA.

15 Mar 2011

Researchers discover new key component in lung cancer spread

Researchers discovered a new, key component in the spread of lung cancer as well as a likely way to block it with drugs now in clinical trial. The study was published today (Monday, March 14) in the Journal of Clinical Investigation.

15 Mar 2011

Medical Science News

Elite controllers' T cells resist HIV-1 infection by selective upregulation of protein p21

NIH awards TriLink $100,000 Phase I SBIR Grant to develop Hot Start approach for Ligase Chain Reaction

Experimental vaccine against human norovirus generates strong, safe immune response in mice

Genomatix launches service model for NGS data analysis

Backscattering interferometry can precisely measure membrane protein interactions

Malaria drug shrinks, slows resistant pancreatic tumors

Protein folding may aid in developing new therapies for brain diseases

Insight into Lyme disease

Anti-cancer drug loaded microcarriers successfully guided to targeted area in the liver

Manchester research offers hope for congenital hyperinsulinism treatment

Researchers identify genetic cause of magnesium deficiency

BRAF gene defect leads to pilocytic astrocytoma in children

Researchers discover molecular switch for insulin secretion

March of Dimes to honor fragile X syndrome researcher with Lifetime Achievement award

Study investigates physiological changes within brain due to Prozac treatment

Study underscores need for monitoring vitamin D levels in all cirrhosis patients

Enzo Life Sciences introduces ELISA system to detect SMN protein

XTIO2 presents XTI 360 ANTI-GERM SYSTEM to 83rd Academy Award-nominees

Ingenuity announces new features to support RNA-Seq workflows, microRNA research in IPA

Researchers discover new key component in lung cancer spread

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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