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First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

Neena Singh, MD, PhD and colleagues at Case Western Reserve University School of Medicine have identified the first disease-specific biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a universally fatal, degenerative brain disease for which there is no cure. sCJD is one of the causes of dementia and typically leads to death within a year of disease onset.

10 Mar 2011

CRT, ICR sign deal with ZoBio to discover and develop cancer drugs

Cancer Research Technology and The Institute of Cancer Research have signed a deal with Dutch drug discovery company, ZoBio BV, to discover and develop drugs to block a DNA repair target which may play a role in cancer cell survival.

10 Mar 2011

Immunologists identify key cell component that triggers allergic responses to cat dander

A breakthrough by scientists at The University of Nottingham could provide hope for any allergy sufferers who have ever had to choose between their health and their household pet.

10 Mar 2011

Researchers pinpoint a protein responsible for fat storage in the body

Scientists have shed light on why some people are apple-shaped and others are pear-shaped.

10 Mar 2011

Study finds synapses between retinal ganglion cells and starburst amacrine cells distributed asymmetrically

The sensory cells in the retina of the mammalian eye convert light stimuli into electrical signals and transmit them via downstream interneurons to the retinal ganglion cells which, in turn, forward them to the brain. The interneurons are connected to each other in such a way that the individual ganglion cells receive visual information from a circular area of the visual field known as the receptive field.

10 Mar 2011

ITCs in vegetables appear to target and block p53 gene linked with cancer

Scientists are reporting discovery of a potential biochemical basis for the apparent cancer-fighting ability of broccoli and its veggie cousins. They found for the first time that certain substances in the vegetables appear to target and block a defective gene associated with cancer.

10 Mar 2011

Study reveals flexibility of neuronal processes underlying conscious perception

Our brains process many more stimuli than we become aware of. Often images enter our brain without being noticed: visual information is being processed, but does not reach consciousness, that is, we do not have an impression of it. Then, what is the difference between conscious and unconscious perception, and can both forms of perception be changed through practice?

10 Mar 2011

CUBN gene mutation linked with albuminuria in individuals with or without diabetes

A team of researchers from the United States and Europe has identified a single genetic mutation in the CUBN gene that is associated with albuminuria both with and without diabetes. Albuminuria is a condition caused by the leaking of the protein albumin into the urine, which is an indication of kidney disease.

9 Mar 2011

Predictability can improve multitasking

Researchers from Rice University and Georgia Institute of Technology have found support for the theory that the brain has three concentric layers of working memory where it stores readily available items. Memory researchers have long debated whether there are two or three layers and what the capacity and function of each layer is.

9 Mar 2011

KineMed extends collaboration with BMY to identify and characterize Alzheimer's biomarkers

KineMed, Inc. announced today the extension of its collaboration with Bristol-Myers Squibb in the area of Alzheimer's disease and other neurodegenerative conditions.

9 Mar 2011

Atherotech announces Sponsorship Agreement with NLA

Aiming to boost advanced lipoprotein testing in lipid education and management, Atherotech Diagnostics Lab announces its Sponsorship Agreement with the National Lipid Association.

9 Mar 2011

Vermillion's CA125 positive preliminary data against ovarian tumors presented at WCSGO

Vermillion, a molecular diagnostics company, today announced the presentation of positive preliminary data from its collaboration with Johns Hopkins University School of Medicine to identify biomarkers that improve on the specificity of CA125 for the identification of malignant ovarian tumors.

9 Mar 2011

Research shows how tubercle bacterium manages to survive inside body's macrophage cells

Tuberculosis kills two million people each year and is once again gaining ground also in Sweden and other Western countries. Researchers at Linköping University in Sweden are now presenting new findings that show how the tubercle bacterium manages to survive inside the body's macrophage cells in order eventually to blow them up and spread their infection.

9 Mar 2011

RainDance, 454 Life Sciences collaborate to launch core ADME gene screening research panel

RainDance Technologies, Inc., and 454 Life Sciences, a Roche Company, today announced a collaboration for the development and commercialization of a targeted next-generation sequencing (NGS) solution for the simple and cost-effective investigation of drug absorption, distribution, metabolism, and excretion (ADME).

9 Mar 2011

MabCure presents ovarian cancer diagnostic blood test study results at SGO meeting

Biotechnology company MabCure, Inc. is presenting the results of its recently completed study on the diagnosis of ovarian cancer utilizing its proprietary monoclonal antibodies at the annual meeting of the Society of Gynecological Oncologists.

9 Mar 2011

Variation in exposure to sunlight may affect sensitivity of individuals to drugs

A study from the Swedish medical university Karolinska Institutet has shown that the body's ability to break down medicines may be closely related to exposure to sunlight, and thus may vary with the seasons.

9 Mar 2011

Study supports DNA mismatch repair test for bowel cancer

Bowel cancer patients whose tumors contain defects in specific DNA repair systems are much less likely to experience tumour recurrence post surgery, results from a major clinical study have demonstrated.

9 Mar 2011

Wound Repair and Regeneration publishes positive findings from CXM's Matrix Phase 2b clinical study

Cardium Therapeutics today announced the publication of positive findings from the Company's Matrix Phase 2b clinical study.

9 Mar 2011

Right-handers biased to choosing their right hands

The vast majority of humans - over 90% - prefer to use their right hand for most skilled tasks. For decades, researchers have been trying to understand why this asymmetry exists. Why, with our two cerebral hemispheres and motor cortices, are we not equally skilled with both hands?

9 Mar 2011

Batman puts some POW! into physiology studies

What do you have when you line up a martial artist, acrobatic gymnast, police officer, firefighter, NASCAR driver, and NFL running back? "Watson," the IBM super-computer that recently routed humanity's best on Jeopardy might have guessed the answer was "the Village People," to which host Alex Trebek could have replied, "Sorry. The answer we were looking for is 'Batman'." At least that is the correct answer for physiologist E. Paul Zehr.

9 Mar 2011

Medical Science News

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

CRT, ICR sign deal with ZoBio to discover and develop cancer drugs

Immunologists identify key cell component that triggers allergic responses to cat dander

Researchers pinpoint a protein responsible for fat storage in the body

Study finds synapses between retinal ganglion cells and starburst amacrine cells distributed asymmetrically

ITCs in vegetables appear to target and block p53 gene linked with cancer

Study reveals flexibility of neuronal processes underlying conscious perception

CUBN gene mutation linked with albuminuria in individuals with or without diabetes

Predictability can improve multitasking

KineMed extends collaboration with BMY to identify and characterize Alzheimer's biomarkers

Atherotech announces Sponsorship Agreement with NLA

Vermillion's CA125 positive preliminary data against ovarian tumors presented at WCSGO

Research shows how tubercle bacterium manages to survive inside body's macrophage cells

RainDance, 454 Life Sciences collaborate to launch core ADME gene screening research panel

MabCure presents ovarian cancer diagnostic blood test study results at SGO meeting

Variation in exposure to sunlight may affect sensitivity of individuals to drugs

Study supports DNA mismatch repair test for bowel cancer

Wound Repair and Regeneration publishes positive findings from CXM's Matrix Phase 2b clinical study

Right-handers biased to choosing their right hands

Batman puts some POW! into physiology studies

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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