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Genetic variants determine severity of HCV-related graft disease and antiviral treatment response

German researchers have found a significant association of IL28B genotypes to interferon-based antiviral treatment outcome, and to graft inflammation caused by hepatitis C virus (HCV). The study determined that the presence of G-allele serves as a marker for severe HCV-induced graft inflammation, as well as a predictor for unsuccessful treatment.

3 Mar 2011

FADD protein discovery can lead to better cancer and autoimmune disease drugs

Reporting in Nature, scientists from Thomas Jefferson University have determined that a single protein called FADD controls multiple cell death pathways, a discovery that could lead to better, more targeted autoimmune disease and cancer drugs.

3 Mar 2011

Turmeric may be 'the right spice' to fight colon cancer

Turmeric, a bright yellow spice from south Asia belonging to the ginger family, is the main ingredient in curries - and ancient wisdom suggests that it's also good for your health. Taking this wisdom to the laboratory, Tel Aviv University researchers have discovered that turmeric's active ingredient called curcumin amplifies the therapeutic activity of highly toxic anti-inflammatory drugs used to fight colon cancer when used at high doses.

3 Mar 2011

Scientists provide new insight into mechanisms controlling programmed cell death pathways

Work led by St. Jude Children's Research Hospital investigators provides fresh insight into mechanisms controlling programmed cell death pathways and offers new targets in the fight against cancer and virus-infected cells

3 Mar 2011

Protein serum amyloid A could be a potential diagnostic biomarker for lung cancer

Scientists are reporting discovery of a protein in the blood of lung cancer patients that could be used in a test for the disease - difficult to diagnose in its earliest and most treatable stages - and to develop drugs that stop lung cancer from spreading. Their study appears in ACS's Journal of Proteome Research.

3 Mar 2011

Osiris completes patient enrollment in Prochymal Phase 2 trial to treat heart attack

Osiris Therapeutics, Inc., today announced that it has successfully completed enrollment in a Phase 2 clinical trial evaluating Prochymal, an adult mesenchymal stem cell therapy, in patients experiencing their first heart attack.

3 Mar 2011

Tobacco smoking leads to less activity in the 'executive center' of brain

Tobacco smoking is the leading preventable cause of death and disease in the U.S., with more than 400,000 deaths each year attributable to smoking or its consequences. And yet teens still smoke. Indeed, smoking usually begins in the teen years, and approximately 80 percent of adult smokers became hooked by the time they were 18. Meanwhile, teens who don't take up smoking usually never do.

3 Mar 2011

New microfluidic device may help clinicians to improve cancer therapy

Manipulation of cells by a new microfluidic device may help clinicians improve a promising cancer therapy that harnesses the body's own immune cells to fight such diseases as metastatic melanoma, non-Hodgkin's lymphoma, chronic lymphocytic leukemia and neuroblastoma.

3 Mar 2011

Promising new way to lower cholesterol production

A promising new way to inhibit cholesterol production in the body has been discovered, one that may yield treatments as effective as existing medications but with fewer side-effects.

3 Mar 2011

New study: Lower potassium levels may help explain racial disparity in type 2 diabetes

Lower potassium levels in the blood may help explain why African-Americans are twice as likely to be diagnosed with type 2 diabetes as whites, according to a new study by Johns Hopkins researchers.

3 Mar 2011

ASU receives W. M. Keck $1 million grant to build next-generation 3D imaging microscope

The W. M. Keck Foundation has awarded Arizona State University a $1 million grant to the team of scientists led by Deirdre Meldrum, Ph.D., at the Biodesign Institute.

2 Mar 2011

Scientists discover specific type of human cell to treat spinal cord injuries

For the first time, scientists discovered that a specific type of human cell, generated from stem cells and transplanted into spinal cord injured rats, provide tremendous benefit, not only repairing damage to the nervous system but helping the animals regain locomotor function as well.

2 Mar 2011

Study identifies key gene mutation responsible for type 2 diabetes in nearly 10% of patients

A multinational study has identified a key gene mutation responsible for type 2 diabetes in nearly 10 percent of patients of white European ancestry.

2 Mar 2011

Common fungus might serve as therapeutic agent for plant and human health

Researchers have come closer to understanding how a common fungus "makes its living in the soil," which could lead to its possible "career change" as a therapeutic agent for plant and human health.

2 Mar 2011

FDA clears Meridian's illumigene C. difficile molecular amplification test

Meridian Bioscience, Inc., Cincinnati, Ohio today announced that it has received clearance from the U.S. Food and Drug Administration for a new pediatric claim for its illumigene C. difficile molecular amplification test. C. difficile is a bacterium that is frequently associated with antibiotic therapy often causing diarrhea and, in severe cases, a life-threatening inflammation of the colon.

2 Mar 2011

Cellastim and Optiferrin enable development of xeno-free and blood product-free expansion media

A recent study demonstrated that Cellastim and Optiferrin deliver superior xeno-free and animal-free solutions for primary cell and stem cell expansion media.

2 Mar 2011

Research: Blocking two cell DNA repair routes at once can provide new way to treat bowel cancer

Cancer Research UK-funded scientists have discovered that blocking two cell DNA repair routes at once could provide a completely new way to treat bowel cancer and potentially other cancers, according to research published in Cancer Research, today.

2 Mar 2011

Cord Blood America purchases all UCB samples and related lab equipment from RGI

Cord Blood America, Inc., the umbilical cord blood stem cell preservation company, focused on bringing the life saving potential of cord blood stem cells to families nationwide and internationally, announced today that it has purchased all the umbilical cord blood samples and the related laboratory equipment from Reproductive Genetics Institute, Inc., based in Chicago, Illinois.

2 Mar 2011

WARFARIN study to explore impact of genetic testing on individualized dosing

Iverson Genetic Diagnostics, Inc. announced today that the WARFARIN Study was initiated in major hospital systems nationwide to assess the utility of genetic testing to determine a personalized warfarin dose for individual patients to reduce their risk of serious bleeding or clotting events.

2 Mar 2011

Self-perception of the body linked with general self-esteem

Low self-esteem is associated with a greater risk of mental health problems such as eating disorders and depression. From a public health perspective, it is important for staff in various health-related professions to know about self-esteem. However, there is a vast difference between the research-based knowledge on self-esteem and the simplified popular psychology theories that are disseminated through books and motivational talks, reveals research from the University of Gothenburg.

2 Mar 2011

Medical Science News

Genetic variants determine severity of HCV-related graft disease and antiviral treatment response

FADD protein discovery can lead to better cancer and autoimmune disease drugs

Turmeric may be 'the right spice' to fight colon cancer

Scientists provide new insight into mechanisms controlling programmed cell death pathways

Protein serum amyloid A could be a potential diagnostic biomarker for lung cancer

Osiris completes patient enrollment in Prochymal Phase 2 trial to treat heart attack

Tobacco smoking leads to less activity in the 'executive center' of brain

New microfluidic device may help clinicians to improve cancer therapy

Promising new way to lower cholesterol production

New study: Lower potassium levels may help explain racial disparity in type 2 diabetes

ASU receives W. M. Keck $1 million grant to build next-generation 3D imaging microscope

Scientists discover specific type of human cell to treat spinal cord injuries

Study identifies key gene mutation responsible for type 2 diabetes in nearly 10% of patients

Common fungus might serve as therapeutic agent for plant and human health

FDA clears Meridian's illumigene C. difficile molecular amplification test

Cellastim and Optiferrin enable development of xeno-free and blood product-free expansion media

Research: Blocking two cell DNA repair routes at once can provide new way to treat bowel cancer

Cord Blood America purchases all UCB samples and related lab equipment from RGI

WARFARIN study to explore impact of genetic testing on individualized dosing

Self-perception of the body linked with general self-esteem

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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