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U.S.-Chile collaborate to study new long-acting local anesthetic derived from algae

A U.S.-Chile collaboration is bringing surgical patients closer to having a long-acting local anesthetic. In a randomized, double-blind trial, patients given neosaxitoxin, a new local anesthetic derived from algae, had significantly less postoperative pain and recovered about two days sooner than those given the commonly used local anesthetic bupivacaine.

25 Feb 2011

New study discloses mechanism controlling Rb2/p130 gene expression in lung cancer cells

Despite innumerable studies on lung cancer, many aspects of the disease have yet to be understood, including the role played by the retinoblastoma-related protein Rb2/p130 in the evolution of the disease.

25 Feb 2011

Discovery highlights unexpected role for killer protein in 'autophagy'

Scientists at Trinity College Dublin have made an important discovery concerning how fledgling cancer cells self-destruct, which has the potential of impacting on future cancer therapies. The Trinity research group, led by Smurfit Professor of Medical Genetics, Professor Seamus Martin and funded by Science Foundation Ireland, has just published their findings in the internationally renowned journal, Molecular Cell.

25 Feb 2011

Stallergenes inaugurates new pollen-production factory

On 20 January, Stallergenes, the leading company worldwide in sublingual immunotherapy treatments for respiratory allergies, inaugurated its new pollen-production site in Amilly (Loiret department).

25 Feb 2011

Researchers explain genetic differences that distinguish early-transmitting HIVs-viruses

A new finding from scientists at the National Institutes of Health could help efforts to design vaccines and other prevention tools to block HIV in the early stages of sexual transmission, before infection takes hold. Researchers at the NIH National Institute of Allergy and Infectious Diseases have helped explain genetic differences that can distinguish some early-transmitting HIVs-viruses found in an infected individual within the first month after infection-from forms of HIV isolated later in infection.

25 Feb 2011

Journal of Clinical Virology publishes positive outcome from CMX001 treatment against AdV infection

Chimerix, Inc., a pharmaceutical company developing orally-available antiviral therapeutics, today announced the publication of the first reported case in which adenovirus infection was successfully eradicated following treatment with its broad-spectrum antiviral drug, CMX001.

25 Feb 2011

Meditation leads to stronger mind-body connection than dancing

The body is a dancer's instrument, but is it attuned to the mind? A new study from the University of California, Berkeley, suggests that professional ballet and modern dancers are not as emotionally in sync with their bodies as are people who regularly practice meditation.

25 Feb 2011

Evolutionary changes may have influenced metabolism and increased risk of diabetes

Researchers at the University of California, San Diego School of Medicine and Rady Children's Hospital-San Diego say an evolutionary gene mutation that occurred in human millions of years ago and our subsequent inability to produce a specific kind of sugar molecule appears to make people more vulnerable to developing type 2 diabetes, especially if they're overweight.

25 Feb 2011

Research sheds new light on problem of insulin resistance in type 2 diabetes

A research team, led by La Jolla Institute scientist Joel Linden, Ph.D., has shed new light on the problem of insulin resistance, and identified the key participants in a molecular pathway that holds therapeutic promise for reducing the severity of type 2 diabetes.

25 Feb 2011

Study demonstrates ability of cobas HPV Test to detect HPV-16, HPV-18 genotypes linked to cervical cancer

Roche announced that a study published online today in the American Journal of Clinical Pathology demonstrated the ability of the cobas HPV Test to individually detect HPV-16 and HPV-18, two of the highest risk HPV genotypes causing 70 percent of cervical cancer cases.

From Roche Sequencing and Life Science 25 Feb 2011

Researchers capture complexities of breast cancer tumours to improve treatment, diagnostics

Breast cancer can develop very differently in different women. Researchers in Norway are improving breast cancer diagnostics and treatment by identifying the various tumour types. The objective is to find out as much as possible about the various tumour types so that each patient can receive precisely the right treatment at the right time.

25 Feb 2011

Radioactive tracing agent can identify tumor-draining sentinel nodes in breast cancer, melanoma patients

Researchers say a new kind of tracing agent is more accurate than current methods in helping identify tumor-draining sentinel lymph nodes in breast cancer and melanoma patients. That's the finding in a new study that appears in the online version of the Annals of Surgical Oncology.

25 Feb 2011

More than one way to silence gene activity

There's more than one way to silence gene activity, according to a Michigan State University researcher.

25 Feb 2011

Simpler method of making water-soluble short protein chains with spiral structures

Researchers have developed a simple method of making short protein chains with spiral structures that can also dissolve in water, two desirable traits not often found together. Such structures could have applications as building blocks for self-assembling nanostructures and as agents for drug and gene delivery.

25 Feb 2011

PACAP hormone levels linked to post-traumatic stress disorder

High blood levels of a hormone produced in response to stress are linked to post-traumatic stress disorder in women but not men, a study from researchers at Emory University and the University of Vermont has found.

25 Feb 2011

Scientists find p27Kip1 protein expression in adult and aged human inner ear

In collaboration with scientists and clinicians from the University of California Los Angeles, scientists from Sound Pharmaceuticals have found p27Kip1 to be expressed in the adult and aged human inner ear including the auditory and vestibular sensory organs.

25 Feb 2011

Maternal fructose intake during pregnancy leads to sex-specific changes in fetal, neonatal endocrinology

A recent study accepted for publication in Endocrinology, a publication of The Endocrine Society, reports for the first time that maternal fructose intake during pregnancy results in sex-specific changes in fetal and neonatal endocrinology.

25 Feb 2011

Study: Heparin plays a key role in mast cell-driven allergic and inflammatory reactions

Heparin plays a key role in allergic and inflammatory reactions driven by mast cells, scientists from Karolinska Institutet in Sweden shows in an international collaboration involving colleagues from Germany and Switzerland. The study is published in the recent issue of Immunity, and sheds some new light on the biological function of heparin.

25 Feb 2011

Study: AEG-1 expression predicts erlotinib treatment response in patients with EGFR-mutant lung cancer

Spanish researchers have identified a gene whose expression level strongly predicts how well certain lung cancer patients will respond to treatment with the drug erlotinib.

25 Feb 2011

Role of serotonin in autism spectrum disorders

Mouse models are yielding important clues about the nature of autism spectrum disorders, which impact an estimated one in 110 children in the U.S. In labs at the UT Health Science Center San Antonio, researchers are studying strains of mice that inherently mimic the repetitive and socially impaired behaviors present in these disorders.

25 Feb 2011

Medical Science News

U.S.-Chile collaborate to study new long-acting local anesthetic derived from algae

New study discloses mechanism controlling Rb2/p130 gene expression in lung cancer cells

Discovery highlights unexpected role for killer protein in 'autophagy'

Stallergenes inaugurates new pollen-production factory

Researchers explain genetic differences that distinguish early-transmitting HIVs-viruses

Journal of Clinical Virology publishes positive outcome from CMX001 treatment against AdV infection

Meditation leads to stronger mind-body connection than dancing

Evolutionary changes may have influenced metabolism and increased risk of diabetes

Research sheds new light on problem of insulin resistance in type 2 diabetes

Study demonstrates ability of cobas HPV Test to detect HPV-16, HPV-18 genotypes linked to cervical cancer

Researchers capture complexities of breast cancer tumours to improve treatment, diagnostics

Radioactive tracing agent can identify tumor-draining sentinel nodes in breast cancer, melanoma patients

More than one way to silence gene activity

Simpler method of making water-soluble short protein chains with spiral structures

PACAP hormone levels linked to post-traumatic stress disorder

Scientists find p27Kip1 protein expression in adult and aged human inner ear

Maternal fructose intake during pregnancy leads to sex-specific changes in fetal, neonatal endocrinology

Study: Heparin plays a key role in mast cell-driven allergic and inflammatory reactions

Study: AEG-1 expression predicts erlotinib treatment response in patients with EGFR-mutant lung cancer

Role of serotonin in autism spectrum disorders

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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