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Natural killer cells promote induction of dry eye disease: New discovery

If you are one of the millions of people around the world who struggle with dry eye disease, good news is on the way. A new research discovery published in the Journal of Leukocyte Biology offers hope for new drugs that treat the cellular cause of the disease rather than its symptoms.

1 Jun 2011

SMPX gene mutation causes hereditary hearing impairment

Excessive noise is not the only thing that causes damage to hearing. In many cases, genetic factors are responsible for the loss of hearing at a young age. Researchers at the Max Planck Institute for Molecular Genetics in Berlin together with colleagues from Nijmegen have discovered a previously unknown genetic cause of progressive hearing impairment: the disease is caused by mutations of the SMPX gene, which is located on the X chromosome.

1 Jun 2011

Women with ovarian cancer could benefit from new targeted testing

Women with ovarian cancer could be helped by a new test that identifies the specific type of tumour they have, a conference will hear this week.

1 Jun 2011

IPSOGEN announces two studies on Genomic Grade test to be presented at ASCO 2011

IPSOGEN SA today announces that two studies on the Genomic Grade test will be presented at the American Society for Clinical Oncology Annual Meeting, that will take place June 3-7, 2011, in Chicago, Ill, USA.

1 Jun 2011

E64d reduces Aβ levels and improves memory function in brains of Alzheimer's disease mice

Researchers at the University of California, San Diego, the Medical University of South Carolina and American Life Science Pharmaceuticals of San Diego have demonstrated that oral administration of a cysteine protease inhibitor, E64d, not only reduces the build-up of β-amyloid in the brains of animal models for Alzheimer's disease, but also results in a substantial improvement in memory deficit.

1 Jun 2011

Suberoylanilide hydroxamic acid holds promise against familial frontotemporal dementia

A drug already approved for people with cancer shows early potential as a therapy for a common form of dementia, UT Southwestern Medical Center researchers report.

1 Jun 2011

Sleep loss reduces healthy young man's testosterone levels

Cutting back on sleep drastically reduces a healthy young man's testosterone levels, according to a study published in the June 1 issue of the Journal of the American Medical Association.

1 Jun 2011

Groundbreaking study identifies neural system responsible for facial recognition

Each time you see a person that you know, your brain rapidly and seemingly effortlessly recognizes that person by his or her face.

1 Jun 2011

Researchers discover new drug target that may effectively prevent onset of Huntington's disease

McMaster University researchers have discovered a new drug target that may be effective at preventing the onset of Huntington's disease, working much the same way heart medications slow the progression of heart disease and reduce heart attacks.

1 Jun 2011

Research: Gene mutation causes eye disease glaucoma

It is a mutation in a gene that causes the eye disease glaucoma, according to collaborative research conducted by Swedish, Tunisian, and American researchers. The findings were recently published in the journal Nature Genetics.

31 May 2011

Almac's main research projects on ovarian, breast cancer to be presented at ASCO 2011

Two of Almac's main research projects have been selected for presentation at the 2011 ASCO meeting. Both of these studies are based on Almac's approach of profiling large clinical datasets and analysing the data for molecular subgroups that can aid in improved diagnosis of cancer by identifying molecular subtypes and by identifying molecular subgroups which are of clinical and therapeutic relevance.

31 May 2011

Scientists develop carbohydrate-based vaccine against C. difficile infection

There is now a promising vaccine candidate for combating the pathogen which causes one of the most common and dangerous hospital infections. An international team of scientists from the Max Planck Institute of Colloids and Interfaces in Potsdam has developed a vaccine based on a carbohydrate against the Clostridium difficile bacterium, which is known to cause serious gastrointestinal diseases mainly in hospitals.

31 May 2011

Heptares, AstraZeneca partner to discover and develop new GPCR drug targets

AstraZeneca and Heptares Therapeutics today announced they have entered a four-year collaboration focused on the potential discovery and development of new medicines targeting G-protein coupled receptors.

31 May 2011

Scientists study key malaria protein structure to demonstrate how cells grow and move

Researchers from the Walter and Eliza Hall Institute have overturned conventional wisdom on how cell movement across all species is controlled, solving the structure of a protein that cuts power to the cell 'motor'. The protein could be a potential drug target for future malaria and anti-cancer treatments.

31 May 2011

Study finds novel site within MS4A gene cluster, confirms presence of SNP linked with Alzheimer's

Recently the number of genes known to be associated with Alzheimer's disease has increased from four to eight, including the MS4A gene cluster on chromosome 11.

31 May 2011

Cancer drug helps prevent hypertensive heart disease

A promising cancer treatment drug can restore function of a heart en route to failure from high blood pressure, researchers at UT Southwestern Medical Center have found.

31 May 2011

CMAJ report outlines challenges, approaches to manage and identify NDM-1 antibiotic resistant enzyme

An enzyme associated with extensive antibiotic resistance called New Delhi metallo---lactamase-1 (NDM-1), endemic in India and Pakistan and spreading worldwide, has been found in two people in the Toronto area, one of whom acquired it in Canada, states a case report in CMAJ.

31 May 2011

Small noncoding RNA spurs Alzheimer's development

Researchers pinpoint a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease or other types of neurodegeneration.

31 May 2011

Study: E-waste linked to adverse effects on human health

In addition to its damaging effect on the environment and its illegal smuggling into developing countries, researchers have now linked e-waste to adverse effects on human health, such as inflammation and oxidative stress - precursors to cardiovascular disease, DNA damage and possibly cancer.

31 May 2011

Mouse Phylogeny Viewer

Laboratory research has always been limited in terms of what conclusions scientists can safely extrapolate from animal experiments to the human population as a whole. Many promising findings in mice have not held up under further experimentation, in part because laboratory animals, bred from a limited genetic foundation, don't provide a good representation of how genetic diversity manifests in the broader human population.

30 May 2011

Medical Science News

Natural killer cells promote induction of dry eye disease: New discovery

SMPX gene mutation causes hereditary hearing impairment

Women with ovarian cancer could benefit from new targeted testing

IPSOGEN announces two studies on Genomic Grade test to be presented at ASCO 2011

E64d reduces Aβ levels and improves memory function in brains of Alzheimer's disease mice

Suberoylanilide hydroxamic acid holds promise against familial frontotemporal dementia

Sleep loss reduces healthy young man's testosterone levels

Groundbreaking study identifies neural system responsible for facial recognition

Researchers discover new drug target that may effectively prevent onset of Huntington's disease

Research: Gene mutation causes eye disease glaucoma

Almac's main research projects on ovarian, breast cancer to be presented at ASCO 2011

Scientists develop carbohydrate-based vaccine against C. difficile infection

Heptares, AstraZeneca partner to discover and develop new GPCR drug targets

Scientists study key malaria protein structure to demonstrate how cells grow and move

Study finds novel site within MS4A gene cluster, confirms presence of SNP linked with Alzheimer's

Cancer drug helps prevent hypertensive heart disease

CMAJ report outlines challenges, approaches to manage and identify NDM-1 antibiotic resistant enzyme

Small noncoding RNA spurs Alzheimer's development

Study: E-waste linked to adverse effects on human health

Mouse Phylogeny Viewer

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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