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New computer application automatically detects subtle epileptic brain lesions in MRI scans

Researchers from the Department of Neurology at NYU Langone Medical Center identified potential benefits of a new computer application that automatically detects subtle brain lesions in MRI scans in patients with epilepsy. In a study published in the February 2011 issue of PLoS ONE, the authors discuss the software's potential to assist radiologists in better identifying and locating visually undetectable, operable lesions.

17 Feb 2011

Muscle, aptly enough, is born of cellular bullying, and not mutual consent

In fact, according to new research from Johns Hopkins, the fusion of muscle cells is a power struggle that involves a smaller mobile antagonist that points at, pokes and finally pushes into its larger, stationary partner using a newly identified finger-like projection.

17 Feb 2011

New method may eliminate colonoscopies

Nobody enjoys colonoscopies, including mice. University of Missouri researchers are excited about the potential of using genetic biomarkers to predict colon cancer caused by inflammation. A new method developed at the MU Research Animal Diagnostic Laboratory (RADIL) could eventually lead to a method that might eliminate colonoscopies altogether.

17 Feb 2011

Avesthagen completes development of microalgae based vegetarian DHA omega 3 essential fatty acid

Avesthagen Limited announced completion of a landmark project for the development of AvestaDHA(TM) - a vegetarian source of DHA (docohexanoic acid) omega 3 essential fatty acid based on an innovative approach using naturally occurring microalgae.

17 Feb 2011

Study sheds light on novel functions of certain PCSK enzymes

Recent studies conducted at the Institut de recherches cliniques de Montr-al on a group of PCSK enzymes could have a positive impact on health, from cholesterol to osteoporosis.

17 Feb 2011

Silver nanoparticle coated 'killer paper' for food packaging

Scientists are reporting development and successful lab tests of "killer paper," a material intended for use as a new food packaging material that helps preserve foods by fighting the bacteria that cause spoilage. The paper, described in ACS's journal, Langmuir, contains a coating of silver nanoparticles, which are powerful anti-bacterial agents.

17 Feb 2011

Potential biomarkers for early diagnosis of ectopic pregnancy

A long, urgent search for proteins in the blood of pregnant women that could be used in early diagnosis of ectopic pregnancy (EP) has resulted in discovery of biomarkers that seem to be specific enough to begin testing in clinical trials, scientists are reporting in a new study in ACS's Journal of Proteome Research.

17 Feb 2011

Impaired brain insulin action may worsen type 2 diabetes

Researchers from Mount Sinai School of Medicine have discovered a novel function of brain insulin, indicating that impaired brain insulin action may be the cause of the unrestrained lipolysis that initiates and worsens type 2 diabetes in humans. The research is published this month in the journal Cell Metabolism.

17 Feb 2011

New fully human monoclonal antibodies to battle Chikungunya

The Singapore Immunology Network (SIgN), an institute of the Agency of Science, Technology and Research (A*STAR), and VIVALIS, a French biopharmaceutical company, announced today the discovery of two new fully human monoclonal antibodies which could battle Chikungunya, a disease that currently has no available vaccine or specific treatment.

16 Feb 2011

Mutations in gene linked to structure of the heart seen in Ebstein's anomaly patients

Ebstein's anomaly is a rare congenital valvular heart disease. Now, in patients with this disease, researchers of the Academic Medical Center Amsterdam in the Netherlands, the University of Newcastle, UK and the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have identified mutations in a gene which plays an important role in the structure of the heart.

16 Feb 2011

Break-induced Replication more likely to cause genetic mutation than normal cell repair

Researchers from Indiana University-Purdue University Indianapolis and Umea- University report in a study published in the February 15, 2011, issue of PLoS Biology that a method by which cells repair breaks in their DNA, known as Break-induced Replication, is up to 2,800 times more likely to cause genetic mutation than normal cell repair.

16 Feb 2011

Bone remodeling inflammatory protein linked to metastatic lung cancer development in mice with breast cancer

When doctors discover high concentrations of regulatory T cells in the tumors of breast cancer patients, the prognosis is often grim, though why exactly has long been unclear.

16 Feb 2011

Assessment of child's learning strategies can reveal signs of vision problems

Parents across Ontario will be soon receiving the second round of newly formatted report cards emphasizing the importance of how students work and how this contributes to their overall academic success. As parents and teachers review each child's progress they may want to consider whether vision problems might be a contributing factor to performance and behaviour in class.

16 Feb 2011

IMGM Labs purchases Fluidigm Access Array system to use in re-sequencing applications

IMGM Laboratories GmbH has purchased a Fluidigm Access Array System to use in its development and validation of targeted re-sequencing applications services.

16 Feb 2011

Study explores role of proline containing peptides in inhibiting anti-apoptotic function of XIAP

Basic and translational research on cancer, and development of new cancer therapeutics, has focused on different aspects of cancer cellular function. One area of focus is the life and death of a cancer cell. Apoptosis, also known as programmed cell death, is a fundamental process of cells including cancer cells. The signal transduction pathways of apoptosis involve many different proteins and their interactions with each other.

16 Feb 2011

WINCS detects and measures serotonin levels in brain through deep brain stimulation

Mayo Clinic researchers have concluded that, through deep brain stimulation, a Wireless Instantaneous Neurotransmitter Concentration System (WINCS) can detect and measure serotonin levels in the brain. The findings suggest that in the future such measurements of serotonin may help establish a therapeutic mechanism of deep brain stimulation for psychiatric disease.

16 Feb 2011

WaferGen offers SNP Genotyping screening with new SmartChip PCR System

WaferGen Biosystems, Inc. a leading developer of state-of-the-art genomic analysis systems, today announced that it is offering an early access program for high-throughput Single Nucleotide Polymorphism Genotyping through its new SmartChip Real-Time PCR System.

16 Feb 2011

Deactivation of tau gene may help reverse memory loss in Alzheimer disease

Amyloid-beta and tau protein deposits in the brain are characteristic features of Alzheimer disease. The effect on the hippocampus, the area of the brain that plays a central role in learning and memory, is particularly severe. However, it appears that the toxic effect of tau protein is largely eliminated when the corresponding tau gene is switched off.

16 Feb 2011

Patient on artificial heart receives heart and kidney transplant

Charles Okeke, the Phoenix husband and father of three, made headlines in May 2010 when he became the first patient in the U.S. to be discharged from a hospital with an artificial heart. With the latest technology, the "Freedom Driver," the man without a heart was able to resume his family life and to be free of the confines of a hospital room.

16 Feb 2011

Novel molecular approach using biomarker can predict colorectal cancer staging, recurrence

A quantitative, molecular analysis of lymph nodes in patients deemed colorectal cancer-free was found to be an effective predictor of recurrence, according to a study from researchers at the Kimmel Cancer Center at Jefferson and published online Feb 9. in Clinical Cancer Research.

16 Feb 2011

Medical Science News

New computer application automatically detects subtle epileptic brain lesions in MRI scans

Muscle, aptly enough, is born of cellular bullying, and not mutual consent

New method may eliminate colonoscopies

Avesthagen completes development of microalgae based vegetarian DHA omega 3 essential fatty acid

Study sheds light on novel functions of certain PCSK enzymes

Silver nanoparticle coated 'killer paper' for food packaging

Potential biomarkers for early diagnosis of ectopic pregnancy

Impaired brain insulin action may worsen type 2 diabetes

New fully human monoclonal antibodies to battle Chikungunya

Mutations in gene linked to structure of the heart seen in Ebstein's anomaly patients

Break-induced Replication more likely to cause genetic mutation than normal cell repair

Bone remodeling inflammatory protein linked to metastatic lung cancer development in mice with breast cancer

Assessment of child's learning strategies can reveal signs of vision problems

IMGM Labs purchases Fluidigm Access Array system to use in re-sequencing applications

Study explores role of proline containing peptides in inhibiting anti-apoptotic function of XIAP

WINCS detects and measures serotonin levels in brain through deep brain stimulation

WaferGen offers SNP Genotyping screening with new SmartChip PCR System

Deactivation of tau gene may help reverse memory loss in Alzheimer disease

Patient on artificial heart receives heart and kidney transplant

Novel molecular approach using biomarker can predict colorectal cancer staging, recurrence

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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