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Nitrate boosts efficiency of mitochondria

The spinach-eating cartoon character Popeye has much to teach us, new research from the Swedish medical university Karolinska Institutet shows. The muscles' cellular power plants - the mitochondria - are boosted by nitrate, a substance found in abundance in vegetables such as lettuce, spinach and beetroot.

2 Feb 2011

Aphios enters subcontract with SAIC-Frederick to develop phospholipid nanoencapsulated camptothecin

Aphios® Corporation today announced that it has entered into a subcontract with SAIC-Frederick, a subsidiary of Science Applications International Corporation, to develop phospholipid nanoencapsulated camptothecin, Camposomes™, for the treatment of pancreatic and other cancers, supporting the NCI Alliance for Nanotechnology.

2 Feb 2011

Multi-national group of researchers announce launch of International Genomics of Alzheimer's Project

The launch of the International Genomics of Alzheimer's Project (IGAP) - a collaboration formed to discover and map the genes that contribute to Alzheimer's disease - was announced today by a multi-national group of researchers including Drs. Lindsay Farrer and Sudha Seshadri at Boston University School of Medicine (BUSM). The collaborative effort, spanning universities from both sides of the Atlantic, will combine the knowledge, staff and resources of four consortia that work on Alzheimer's disease genetics.

2 Feb 2011

Nanotechnology and nanotoxicology

The rapid development of nanotechnology has increased fears about the health risks of nano-objects. Are these fears justified? Do we need a new discipline, nanotoxicology, to evaluate the risks? Empa scientists Harald F. Krug and Peter Wick discuss these questions in the new edition of the journal Angewandte Chemie.

2 Feb 2011

Higher intake of monounsaturated, polyunsaturated fatty acids reduce risk of mild cognitive impairment

Mayo Clinic researchers found that the prevalence of mild cognitive impairment decreased with an increase in the consumption of monounsaturated and polyunsaturated fatty acids. Monounsaturated fatty acids are commonly found in olive oil and canola oils, and polyunsaturated fatty acids, such as Omega 3 or Omega 6 fatty acids, are commonly found in most varieties of nuts, seeds and fish.

2 Feb 2011

Zebrafish research findings may provide potential to improve kidney function in humans

It is estimated that up to 10 percent of the U.S. population may have some form of renal disease, with 450,000 patients with end stage renal disease requiring hemodialysis. Researchers at Brigham and Women's Hospital, Massachusetts General Hospital and the University of Pittsburgh have identified a cell in zebrafish that can be transplanted from one fish to another to regenerate nephrons, providing the potential to improve kidney function.

2 Feb 2011

First commercially available full length human MTOR protein with superior biological activity released

OriGene Technologies, Inc., a gene-centric life sciences company, releases the first commercially available full length human MTOR protein with superior biological activity.

2 Feb 2011

Defective nucleoli linked to Parkinson's disease

"Nucleolus", or small nucleus, is the term coined by early biologists for the tiny structure within the nucleus which they saw under the microscope. In this structure within the nucleus, RNA molecules and proteins are assembled to form ribosomes, the true protein factories of cells.

2 Feb 2011

Drugs affecting brain noradrenaline levels could improve breathing in sleep apnea patients

New research from the University of Toronto could provide some restful nights for the 18 million North Americans who suffer from obstructive sleep apnea.

2 Feb 2011

Researchers find better way to create iPS cells from blood samples

Researchers at Johns Hopkins have found a better way to create induced pluripotent stem cells-adult cells reprogrammed with the properties of embryonic stem cells-from a small blood sample. This new method, described last week in Cell Research, avoids creating DNA changes that could lead to tumor formation.

2 Feb 2011

Microbubble contrast- enhanced ultrasound improves identification of sentinel lymph node in breast biopsies

Using "microbubbles" and ultrasound can mean more targeted breast biopsies for patients with early breast cancer, helping to determine treatment and possibly saving those patients from undergoing a second breast cancer surgery, a new study in shows.

2 Feb 2011

Study finds treatment-related mortality with bevacizumab in cancer patients

Cancer patients treated with the chemotherapy agent bevacizumab may be at an increased risk of treatment-related death when the drug is used in combination with other therapies.

2 Feb 2011

Bioengineers and physician-scientists zap tumors with light-activated nanoparticles

Rice University bioengineers and physician-scientists at Baylor College of Medicine and Texas Children's Hospital have successfully destroyed tumors of human brain cancer cells in the first animal tests of a minimally invasive treatment that zaps glioma tumors with heat. The tests involved nanoshells, light-activated nanoparticles that are designed to destroy tumors with heat and avoid the unwanted side effects of drug and radiation therapies.

2 Feb 2011

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

Scientists discovered a new way breast cancer cells dodge the immune system and promote tumor growth, providing a fresh treatment target in the fight against the disease. While comparable mechanisms to avoid the immune system have been identified in mice with breast and other cancers, the study tested human breast tumor cells, putting researchers closer to understanding how the disease progresses in real patients.

2 Feb 2011

Scientists test new dry powder measles vaccine that can be inhaled

Sustained high vaccination coverage is key to preventing deaths from measles. Despite the availability of a vaccine, measles remains an important killer of children worldwide, particularly in less-developed regions where vaccination coverage is limited. A team of researchers, led by scientists at the Johns Hopkins Bloomberg School of Public Health and the University of Colorado, developed and successfully tested a dry powder, live-attenuated measles vaccine that can be inhaled.

2 Feb 2011

Research discovers new role of TRPV1 receptors in regulation of locomotor activity

Research by a Barrow Neurological Institute scientist on the thermoregulatory effects of a receptor more commonly studied for its role in pain is the cover story in the Feb. 2 issue of the Journal of Neuroscience.

2 Feb 2011

EA sponsors research grant to investigate specific cancers and kinase mutations

Expression Analysis today announced a jointly sponsored research grant for up to eight American Cancer Society Grantees to investigate and draw parallels between specific cancers and recurring mutations in specific kinases, using targeted genome sequencing.

2 Feb 2011

New compound appears to prevent pain crises in sickle cell disease: GHSU

A new compound appears to prevent the traffic jam of cells that causes debilitating pain crises and associated mortality in sickle cell disease, Georgia Health Sciences University researchers report.

1 Feb 2011

PET imaging may play a role in early evaluation of vandetanib response in thyroid cancer

Positron emission tomography can image metabolic changes following treatment with the protein kinase inhibitor vandetanib, helping to define the therapy response or the effectiveness of the therapeutic agent, according to research published in the February issue of The Journal of Nuclear Medicine.

1 Feb 2011

Fluidigm launches new BioMark HD Real-time PCR System for genomic analysis

Fluidigm today introduced the new BioMark HD Real-time PCR System, the company's most advanced instrument for genomic analysis ever. The BioMark HD System is designed for researchers who require the sensitivity and throughput needed to study gene expression down to the single-cell level -- especially those who have limited amounts of sample or study rare populations of cells.

1 Feb 2011

Medical Science News

Nitrate boosts efficiency of mitochondria

Aphios enters subcontract with SAIC-Frederick to develop phospholipid nanoencapsulated camptothecin

Multi-national group of researchers announce launch of International Genomics of Alzheimer's Project

Nanotechnology and nanotoxicology

Higher intake of monounsaturated, polyunsaturated fatty acids reduce risk of mild cognitive impairment

Zebrafish research findings may provide potential to improve kidney function in humans

First commercially available full length human MTOR protein with superior biological activity released

Defective nucleoli linked to Parkinson's disease

Drugs affecting brain noradrenaline levels could improve breathing in sleep apnea patients

Researchers find better way to create iPS cells from blood samples

Microbubble contrast- enhanced ultrasound improves identification of sentinel lymph node in breast biopsies

Study finds treatment-related mortality with bevacizumab in cancer patients

Bioengineers and physician-scientists zap tumors with light-activated nanoparticles

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

Scientists test new dry powder measles vaccine that can be inhaled

Research discovers new role of TRPV1 receptors in regulation of locomotor activity

EA sponsors research grant to investigate specific cancers and kinase mutations

New compound appears to prevent pain crises in sickle cell disease: GHSU

PET imaging may play a role in early evaluation of vandetanib response in thyroid cancer

Fluidigm launches new BioMark HD Real-time PCR System for genomic analysis

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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