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Two defective genes may cause telomere elongations in cancer cells: Study

Scientists at Johns Hopkins have provided more clues to one of the least understood phenomena in some cancers: why the "ends caps" of cellular DNA, called telomeres, lengthen instead of shorten.

1 Jul 2011

Genetic mutations in abnormal bone marrow can predict mortality of MDS patients

For patients with myelodysplastic syndromes (MDS), choosing the appropriate treatment depends heavily on the prognosis. Those patients at the highest risk of dying from their disease are typically offered the most aggressive therapies, while patients at lower risk could live several years with MDS, needing only supportive care or other relatively side-effect free treatments.

1 Jul 2011

Scientists discover enzyme that can regulate breast cancer development

Researchers at Cold Spring Harbor Laboratory (CSHL) have identified an enzyme that appears to be a significant regulator of breast cancer development. Called PTPN23, the enzyme is a member of a family called protein tyrosine phosphatases, or PTPs, that plays a fundamental role in switching cell signaling on and off.

1 Jul 2011

Research sheds light on well-documented 'other-race effect'

Northwestern University researchers have provided new biological evidence suggesting that the brain works differently when memorizing the face of a person from one's own race than when memorizing a face from another race.

1 Jul 2011

New analytical approach can organize large amounts of varied cancer genetic data

The technology that allows scientists to profile the entire genome of individual tumors offers new hope for discovering ways to select the best treatment for each patient's particular type of cancer. However, these profiles produce huge amounts of data, and the volume alone creates unique analytical problems.

1 Jul 2011

Erratic investment responses can make a smart portfolio richer

Playing the stock market can be a risky game. And when the market behaves unpredictably, public fear can lead to erratic investment responses and market chaos.

1 Jul 2011

Epigenetics affects whether or not stem cells differentiate

Adult stem cells and progenitor cells may not come with a clean genetic slate after all. That's because a new report in the FASEB Journal shows that adult stem or progenitor cells have their own unique "epigenetic signatures," which change once a cell differentiates. This is important because epigenetic changes do not affect the actual make up in a cell's DNA, but rather, how that DNA functions.

1 Jul 2011

Study reveals unique pattern of brain activity when false memories are formed

How easy is it to falsify memory? New research at the Weizmann Institute shows that a bit of social pressure may be all that is needed. The study, which appears Friday in Science, reveals a unique pattern of brain activity when false memories are formed - one that hints at a surprising connection between our social selves and memory.

1 Jul 2011

Researchers identify altered expression of endogenous retroviruses in BSE-infected macaques

Prion diseases such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy (BSE) in cattle are transmissible neurodegenerative diseases linked to the aggregation of the prion protein in the central nervous system.

1 Jul 2011

Nicotine receptors play crucial role in social interaction

If you think nicotine receptors are only important to smokers trying to kick the tobacco habit, think again. New research published in the FASEB Journal (http://www.fasebj.org) suggests that these receptors also play an important role in social interaction and the ability to choose between competing motivations.

1 Jul 2011

Genetic variation associated with increased risk of sudden cardiac arrest

A study by a global consortium of physician-scientists has identified a genetic variation that may predispose people to double the risk of having a sudden cardiac arrest, a disorder that gives little warning and is fatal in about 95 percent of cases.

1 Jul 2011

Roche introduces new real-time PCR system

With "Size: Reduced. Fun: Amplified.", Roche Applied Science launched its new real-time PCR system on June 27th, 2011. The small, silent, sleek LightCycler Nano Instrument supports state-of-the-art technology for fast PCR protocols featuring leading edge thermal resolution and reproducibility.

1 Jul 2011

Researchers predict human's desired movements using brain signals

Bringing the real world into the brain scanner, researchers at The University of Western Ontario from The Centre for Brain and Mind (http://www.uwo.ca/its/brain/) can now determine the action a person was planning, mere moments before that action is actually executed.

30 Jun 2011

Exposure to mobile phone derived electromagnetic fields can influence learning processes

High frequency non-ionizing radiation, emitted by mobile phones, is redundantly matter of discussions. The effects of high frequency electromagnetic fields derived from mobile phones have been discussed since the 1950's.

30 Jun 2011

Lotus Tissue Repair to develop DEB protein replacement therapy with $26 million Series A financing

Lotus Tissue Repair, Inc. today announced the closing of a $26 million Series A financing led by Third Rock Ventures. Proceeds of the financing will be used to advance the company's proprietary recombinant collagen type VII (rC7) technology as the first and only protein replacement therapy in development for the treatment of dystrophic epidermolysis bullosa (DEB), an orphan disease that causes devastating skin blisters, morbidity and early mortality.

30 Jun 2011

Study about U.S. attitudes toward human embryonic stem cell research

While research using human embryonic stem cells has roused political controversy for almost two decades, little has been done to scientifically assess American attitudes on the subject. New research from the University of Nevada, Reno provides decision-makers with a much clearer picture of how their constituents truly feel about the subject.

30 Jun 2011

Researchers discover Foxj1 genetic 'conductor' responsible for new brain cell production

A team of North Carolina State University researchers has discovered more about how a gene connected to the production of new brain cells in adults does its job. Their findings could pave the way to new therapies for brain injury or disease.

30 Jun 2011

Serum-free media with growth factors can improve MSCs' cell fate regulation

Mensenchymal stem cells (MSCs), multipotent cells identified in bone marrow and other tissues, have been shown to be therapeutically effective in the immunosuppression of T-cells, the regeneration of blood vessels, assisting in skin wound healing, and suppressing chronic airway inflammation in some asthma cases.

30 Jun 2011

Anabasis, Scil Proteins enter license deal for rhNGF to treat eye diseases

Scil Proteins, a private biopharmaceutical company specialized in the research, development and production of recombinant proteins, today announced that it has signed an agreement with Anabasis Pharma.

30 Jun 2011

Sensitivity of bladder cancer cells linked to chemotherapy and expression of miR-34a gene

Researchers at the UC Davis Cancer Center have discovered a way of sensitizing muscle-invasive bladder cancer cells so that they succumb to the toxic effects of chemotherapy. The finding adds to mounting evidence that tiny strands of RNA - called microRNA - play key roles in some of the deadliest types of cancer.

30 Jun 2011