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First-ever selective irreversible inhibition of viral protease using targeted covalent drug

Avila Therapeutics, Inc., a biotechnology company developing novel targeted covalent drugs, has published research in Nature Chemical Biology demonstrating the first-ever selective irreversible inhibition of a viral protease using a targeted covalent drug.

30 Nov 2010

Genetic screening for Lynch syndrome as cost-effective as other cancer screening procedures

Myriad Genetics, Inc. today said results from a major health economics study in Cancer Prevention Research, a journal of the American Association for Cancer Research (AACR), found that screening for inherited gene mutations in the genes that cause a major colorectal cancer syndrome called Lynch Syndrome, is both medically and cost effective.

30 Nov 2010

New review from JASN highlights hazards of fructose

More and more people have become aware of the dangers of excessive fructose in diet. A new review on fructose in an upcoming issue of the Journal of the American Society of Nephrology (JASN) indicates just how dangerous this simple sugar may be.

30 Nov 2010

Neuroplasticity helps children with learning disabilities improve cognitive functioning capacities

Brain School, a new book from Eaton Arrowsmith School's (EAS) founder and director, Howard Eaton, tells the amazing story of how children with learning disabilities such as Dyslexia, Nonverbal Learning Disabilities and ADHD overcame educational obstacles by reorganizing their brains.

30 Nov 2010

Majority of Americans and Canadians are getting enough vitamin D and calcium, says report

The majority of Americans and Canadians are getting enough vitamin D and calcium to meet their needs, says a new report from the Institute of Medicine. Most people up to age 70 need no more than 600 international units, or IUs, of vitamin D per day, and those 71 and older may need as much as 800 IUs, the report finds. The amount of calcium needed ranges, based on age, from 700 to 1,300 milligrams per day.

30 Nov 2010

CAMH neuroscientists develop novel protein peptide for targeted treatment of depression

Neuroscientists at the Centre for Addiction and Mental Health (CAMH) have developed a protein peptide that may be a novel type of highly targeted treatment for depression with a low side-effect profile. Depression affects one in ten Canadians at some time in their lives and is a leading cause of disability worldwide.

30 Nov 2010

Molecular switch plays crucial role in addictive behavior and memory processes

Learning and memory formation are based on the creation of new connections between neurons in the brain. Also, behaviors such as nicotine addiction manifest themselves in long-term changes of neuronal connectivity and can - at least in this respect - be viewed as a form of learning.

30 Nov 2010

GeoVax supports Bionor's Phase 2b trial of therapeutic HIV/AIDS vaccine

GeoVax Labs, Inc., an Atlanta-based, biopharmaceutical company developing human vaccines for HIV/AIDS (HIV-1, Human Immunodeficiency Virus), announced it was pleased to learn of the partial success observed in the recently completed Phase 2b trial of a therapeutic HIV/AIDS vaccine produced by Bionor Immuno AS of Oslo, Norway.

30 Nov 2010

New findings could drive medical advances in genetic disorders that cause infertility

A hormone responsible for the onset of puberty can end up stuck in the wrong part of the body if the nerve pathways responsible for its transport to the brain fail to develop properly, according to research funded by the Biotechnology and Biological Sciences Research Council (BBSRC).

30 Nov 2010

New study may lead to non-medicinal methods of eradicating Hamburger disease

Hamburger disease, a debilitating form of food poisoning, may be a thing of the past. New findings from an international research collaboration conducted by the French National Institute for Agronomic Research (INRA), involving the Universit- de Montr-al are the first to show how the contaminating E.coli bacterium is able to survive in the competitive environment of a cow's intestine by scavenging specific food sources.

30 Nov 2010

IOM report updates DRIs levels of Vitamin D, calcium

Vitamin D and calcium have been the focus of much research since the Institute of Medicine set nutritional reference values for them in 1997. Known as Dietary Reference Intakes, the values for these and other nutrients serve as a guide for good nutrition and provide the scientific basis for the development of food guidelines in both the United States and Canada. Updated DRIs for these two nutrients are presented in a new IOM report, Dietary Reference Intakes for Calcium and Vitamin D, which will be released on Tuesday, Nov. 30.

30 Nov 2010

Scientists discover a new method to produce gold nanoparticles

Gold nanoparticles, tiny pieces of gold so small that they can't be seen by the naked eye, are used in electronics, healthcare products and as pharmaceuticals to fight cancer. Despite their positive uses, the process to make the nanoparticles requires dangerous and extremely toxic chemicals. While the nanotechnology industry is expected to produce large quantities of nanoparticles in the near future, researchers have been worried about the environmental impact of the global nanotechnological revolution.

30 Nov 2010

Children with autism improve creative skills by playing with building blocks

In an attempt to help children with autism learn the building blocks of creativity, researchers at the University of Rochester Medical Center (URMC) tapped a toy box staple for help - legos. By building lego structures in new and unique ways, children with autism spectrum disorders (ASD) learned to use creativity, an important skill that they had seen as very challenging prior to the study.

30 Nov 2010

Scientists uncover new regulatory mechanism in body's response to eliminate pathogens

A team of scientists from The Scripps Research Institute have uncovered a previously unknown regulatory mechanism in the body's response to eliminate pathogens, such as bacteria and viruses. The findings challenge a long-held dogma in the field of immunology and have potential implications for far-ranging topics from how vaccines should be administered to the origin of autoimmunity.

30 Nov 2010

Research finds alteration in KBTBD13 protein causes nemaline myopathy

Researchers from the Department of Anesthesiology, Uniformed Services University of the Health Sciences (USU), along with research teams from the National Institutes of Health and from Australia, the Netherlands and Spain, have identified a novel gene on chromosome 15q that, when altered, causes nemaline myopathy with cores, a rare inherited muscle disorder. The gene encodes a member of the BTB/Kelch family of proteins.

30 Nov 2010

Drugs that target DNA in later-stage cancers could be effective in treating breast tumors

Breast cancers that arise sporadically, rather than through inheritance of certain genes, likely start with defects of DNA repair mechanisms that allow environmentally triggered mutations to accumulate, according to researchers at the University of Pittsburgh School of Medicine, Magee-Womens Hospital of UPMC and the University of Pittsburgh Cancer Institute.

30 Nov 2010

New tool to trace metabolism of carotenoids in human body

The University of Illinois scientists who linked eating tomatoes with a reduced risk of prostate cancer have developed a tool that will help them trace the metabolism of tomato carotenoids in the human body. And they've secured funding from the National Institutes of Health to do it.

30 Nov 2010

Study confirms difference in coronary artery disease pathways among Caucasians, African Americans

In a study being presented today at the annual meeting of the Radiological Society of North America (RSNA), researchers say they may have an explanation as to why African Americans, despite having lower amounts of coronary artery calcification, are at increased risk for heart attacks and other cardiovascular events compared with Caucasians.

30 Nov 2010

Study: Mature blood cells communicate with parent stem cells

A new study by researchers at the Walter and Eliza Hall Institute in Melbourne, Australia, has shown that mature blood cells can communicate with, and influence the behaviour of, their stem cell 'parents'.

30 Nov 2010

Overexpression of microRNA 125b can cause leukemia: Research

Whitehead Institute researchers have shown in mouse models that overexpression of the microRNA 125b (miR-125b) can independently cause leukemia and accelerate the disease's progression. Their results are published in this week's online edition of the Proceedings of the National Academy of Sciences (PNAS).

30 Nov 2010

Medical Science News

First-ever selective irreversible inhibition of viral protease using targeted covalent drug

Genetic screening for Lynch syndrome as cost-effective as other cancer screening procedures

New review from JASN highlights hazards of fructose

Neuroplasticity helps children with learning disabilities improve cognitive functioning capacities

Majority of Americans and Canadians are getting enough vitamin D and calcium, says report

CAMH neuroscientists develop novel protein peptide for targeted treatment of depression

Molecular switch plays crucial role in addictive behavior and memory processes

GeoVax supports Bionor's Phase 2b trial of therapeutic HIV/AIDS vaccine

New findings could drive medical advances in genetic disorders that cause infertility

New study may lead to non-medicinal methods of eradicating Hamburger disease

IOM report updates DRIs levels of Vitamin D, calcium

Scientists discover a new method to produce gold nanoparticles

Children with autism improve creative skills by playing with building blocks

Scientists uncover new regulatory mechanism in body's response to eliminate pathogens

Research finds alteration in KBTBD13 protein causes nemaline myopathy

Drugs that target DNA in later-stage cancers could be effective in treating breast tumors

New tool to trace metabolism of carotenoids in human body

Study confirms difference in coronary artery disease pathways among Caucasians, African Americans

Study: Mature blood cells communicate with parent stem cells

Overexpression of microRNA 125b can cause leukemia: Research

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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