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New research sheds light on how neurons make connections with one another

Newly published research led by Professor Z. Josh Huang, Ph.D., of Cold Spring Harbor Laboratory sheds important new light on how neurons in the developing brain make connections with one another.

22 Dec 2010

New online tool helps scientists to find gene promoters

Researchers at The Wistar Institute announce the release of an online tool that will help scientists find "gene promoters"—regions along a DNA strand that tell a cell's transcription machinery where to start reading in order to create a particular protein.

22 Dec 2010

Spinal Botox injection reduces pain

Botulinum neurotoxin type A (BoNT/A)—better known as Botox—reduces responses to an inflammation-related pain stimulus when injected into the spinal canal in mice, reports a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

22 Dec 2010

UH scientist evaluates microRNAs as potential treatment strategy for ovarian cancer

The day when an ovarian cancer patient can treat her tumor with a single, painless pill instead of a toxic drug cocktail is the ultimate goal of the pioneering research of a University of Houston scientist.

22 Dec 2010

Altering balance among immune system cells could hold potential for T2D-associated inflammation treatment

Researchers from Boston University School of Medicine (BUSM) have demonstrated that certain T cells require input from monocytes in order to maintain their pro-inflammatory response in people with type 2 diabetes (T2D). The study also showed, for the first time, how a loss in homeostasis in this group of T cells most likely promotes chronic inflammation associated with T2D.

22 Dec 2010

Popular Science magazine honors ONR-funded researchers on 2010 'Brilliant 10' list

Dubbed the "Brilliant 10" by Popular Science, two researchers on the magazine's recently released 2010 list of top young scientists have received funding from the Office of Naval Research (ONR).

22 Dec 2010

People with type 1 diabetes could grow their own insulin-producing cells, say researchers

At the annual meeting of the American Society for Cell Biology last week in Philadelphia, researchers from Georgetown University Medical Center in Washington, D.C., announced that it may be possible for people with type 1 diabetes to grow their own insulin-producing cells, a breakthrough that could lead to a cure for the disease.

22 Dec 2010

AIDS patients with serum biomarkers are predisposed to immune reconstitution inflammatory syndrome

A study in this week's PLoS Medicine suggests that AIDS patients with cryptococcal meningitis who start HIV therapy are predisposed to immune reconstitution inflammatory syndrome - an exaggerated inflammatory immune response that kills up to one-third of affected people - if they have biomarkers in their blood showing evidence of a damaged immune system that is not capable of clearing the fungal infection.

22 Dec 2010

High LSC scores associated with adverse outcomes in AML patients

In an examination of leukemic stem cells (LSC), researchers have found that patients with acute myeloid leukemia who had higher activity of certain LSC genes had worse overall, event-free and relapse-free survival, according to a study in the December 22/29 issue of JAMA.

21 Dec 2010

Spirulina dietary supplement may provide clinical benefits for ALS patients

Nutritional supplementation with Spirulina, a nutrient-rich, blue-green algae, appeared to provide neuroprotective support for dying motor neurons in a mouse model of amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, University of South Florida neuroscientists have found.

21 Dec 2010

New genetic alteration predisposes individuals to Cowden syndrome

Researchers have identified a new genetic alteration that predisposes individuals to Cowden syndrome, a rare disorder that is characterized by high risks of breast, thyroid and other cancers, according to preliminary research published in the December 22/29 issue of JAMA.

21 Dec 2010

Study on why whole orange is better than components

In time for Christmas, BYU nutritionists are squeezing all the healthy compounds out of oranges to find just the right mixture responsible for their age-old health benefits.

21 Dec 2010

Whites with mutations more likely to be susceptible to cocaine abuse

Nearly one in five whites could carry a genetic variant that substantially increases their odds of being susceptible to severe cocaine abuse, according to new research.

21 Dec 2010

Study provides evidence on prevalence of two separate mosquito species which carry malaria parasite

In notable back-to-back papers appearing in the prestigioous journal Science in October, teams of researchers, one led by Nora Besansky, a professor of biological sciences and a member of the Eck Institute for Global Health at the University of Notre Dame, provided evidence that Anopheles gambiae, which is one of the major mosquito carriers of the malaria parasite in Sub-Saharan Africa, is evolving into two separate species with different traits.

21 Dec 2010

Researchers present definitive explanation of how fibrotic cells destroy human liver

In the latest of a series of related papers, researchers at the University of California, San Diego School of Medicine, with colleagues in Austria and elsewhere, present a new and more definitive explanation of how fibrotic cells form, multiply and eventually destroy the human liver, resulting in cirrhosis. In doing so, the findings upend the standing of a long-presumed marker for multiple fibrotic diseases and reveal the existence of a previously unknown kind of inflammatory white blood cell.

21 Dec 2010

Biomagnification of nanomaterials in simple food chain demonstrated

An interdisciplinary team of researchers at UC Santa Barbara has produced a groundbreaking study of how nanoparticles are able to biomagnify in a simple microbial food chain.

21 Dec 2010

XFELs technology can track damaged membrane protein structure

Australian researchers have identified a way to measure the structure of membrane proteins despite being damaged when using X-ray Free-Electron Lasers, a discovery that will help fast track the development of targeted drugs using emerging XFELs technology.

21 Dec 2010

Exiqon completes discovery phase program for early detection of colorectal cancer in blood

Exiqon A/S today announced the completion of the discovery phase in its program for early detection of colorectal cancer in blood.

21 Dec 2010

Researchers develop new malaria vaccine strategy based on ingestion of genetically modified starch

Researchers from two laboratories in northern France have successfully vaccinated and protected mice by feeding them starch derived from green algae and genetically modified to carry vaccine proteins.

21 Dec 2010

Study reveals novel role of adenosine signaling in sickle cell disease

Metabolon, Inc., the leader in metabolomics, biomarker discovery and analysis, announces the publication of "Novel Role of Adenosine Signaling in Sickle Cell Disease", in Nature Medicine. Application of non-targeted biochemical profiling (metabolomics) to a mouse model of sickle cell disease (SCD) revealed a detrimental role of adenosine signaling in SCD and suggested novel therapeutic targets. The study was carried out in collaboration with The University of Texas Health Science Center at Houston.

21 Dec 2010

Medical Science News

New research sheds light on how neurons make connections with one another

New online tool helps scientists to find gene promoters

Spinal Botox injection reduces pain

UH scientist evaluates microRNAs as potential treatment strategy for ovarian cancer

Altering balance among immune system cells could hold potential for T2D-associated inflammation treatment

Popular Science magazine honors ONR-funded researchers on 2010 'Brilliant 10' list

People with type 1 diabetes could grow their own insulin-producing cells, say researchers

AIDS patients with serum biomarkers are predisposed to immune reconstitution inflammatory syndrome

High LSC scores associated with adverse outcomes in AML patients

Spirulina dietary supplement may provide clinical benefits for ALS patients

New genetic alteration predisposes individuals to Cowden syndrome

Study on why whole orange is better than components

Whites with mutations more likely to be susceptible to cocaine abuse

Study provides evidence on prevalence of two separate mosquito species which carry malaria parasite

Researchers present definitive explanation of how fibrotic cells destroy human liver

Biomagnification of nanomaterials in simple food chain demonstrated

XFELs technology can track damaged membrane protein structure

Exiqon completes discovery phase program for early detection of colorectal cancer in blood

Researchers develop new malaria vaccine strategy based on ingestion of genetically modified starch

Study reveals novel role of adenosine signaling in sickle cell disease

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

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