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Caspase inhibition can prevent brain inflammation in neurological diseases

Neurodegenerative diseases like Alzheimer's and Parkinson's are partly attributable to brain inflammation. Researchers at Karolinska Institutet now demonstrate in a paper published in Nature that a well-known family of enzymes can prevent the inflammation and thus constitute a potential target for drugs.

10 Mar 2011

St. Joseph's Hospital launches new neuromodulation center in Barrow

St. Joseph's Hospital and Medical Center's Barrow Neurological Institute has received a $10.1 million donation, the largest single gift in the organization's history and one of the biggest ever given to any Arizona hospital.

10 Mar 2011

First recording of cortically induced neural activity of basal ganglia in Parkinson's disease, dystonia during DBS

Movement disorders such as Parkinson's diseases and dystonia are caused by abnormal neural activity of the basal ganglia located deep in the brain. The basal ganglia are connected to the cerebral cortex in the brain surface through complex neural circuits.

10 Mar 2011

New study sheds 'light' on intricate brain cell connections responsible for anxiety

A new study sheds light--both literally and figuratively--on the intricate brain cell connections responsible for anxiety.

10 Mar 2011

Study: High volume music players can cause neurophysiological changes

Growing numbers of people enjoy listening to music on portable music players or cell phones, and many tend to turn up the volume, especially in noisy surroundings. In a study published March 2, 2011 in the open-access journal PLoS ONE, researchers explore the potential effects of this behavior on hearing.

10 Mar 2011

Experimental drug effectively shuts off MCL1 gene and induces apoptosis

Predictive Biomarker Sciences (PBS-Bio) has uncovered how the experimental drug UNBS1450, produced by Unibioscreen, kills cancer cells.

10 Mar 2011

Swine flu virus may evolve into a deadlier form

In the fall of 1917, a new strain of influenza swirled around the globe. At first, it resembled a typical flu epidemic: Most deaths occurred among the elderly, while younger people recovered quickly. However, in the summer of 1918, a deadlier version of the same virus began spreading, with disastrous consequence. In total, the pandemic killed at least 50 million people - about 3 percent of the world's population at the time.

10 Mar 2011

Blood biomarker may help decide intake of aspirin or NSAIDs for reduction of cancer risk

The reduced risk of colorectal cancer associated with taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) may be confined to individuals already at risk because of elevations in a particular inflammatory factor in the blood.

10 Mar 2011

Novel sortase-based techniques allow modification of a large variety of different proteins

Whitehead Institute scientists have created a method that site-specifically modifies proteins to exert control over their properties when administered therapeutically. The technique should be useful to increase potency, slow metabolism, and improve thermal stability of therapeutically useful proteins, such as interferon alpha 2 (IFN-alpha 2), which is used to treat variety of diseases, including leukemia, melanoma, and chronic hepatitis C.

10 Mar 2011

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

Neena Singh, MD, PhD and colleagues at Case Western Reserve University School of Medicine have identified the first disease-specific biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a universally fatal, degenerative brain disease for which there is no cure. sCJD is one of the causes of dementia and typically leads to death within a year of disease onset.

10 Mar 2011

CRT, ICR sign deal with ZoBio to discover and develop cancer drugs

Cancer Research Technology and The Institute of Cancer Research have signed a deal with Dutch drug discovery company, ZoBio BV, to discover and develop drugs to block a DNA repair target which may play a role in cancer cell survival.

10 Mar 2011

Immunologists identify key cell component that triggers allergic responses to cat dander

A breakthrough by scientists at The University of Nottingham could provide hope for any allergy sufferers who have ever had to choose between their health and their household pet.

10 Mar 2011

Researchers pinpoint a protein responsible for fat storage in the body

Scientists have shed light on why some people are apple-shaped and others are pear-shaped.

10 Mar 2011

Study finds synapses between retinal ganglion cells and starburst amacrine cells distributed asymmetrically

The sensory cells in the retina of the mammalian eye convert light stimuli into electrical signals and transmit them via downstream interneurons to the retinal ganglion cells which, in turn, forward them to the brain. The interneurons are connected to each other in such a way that the individual ganglion cells receive visual information from a circular area of the visual field known as the receptive field.

10 Mar 2011

ITCs in vegetables appear to target and block p53 gene linked with cancer

Scientists are reporting discovery of a potential biochemical basis for the apparent cancer-fighting ability of broccoli and its veggie cousins. They found for the first time that certain substances in the vegetables appear to target and block a defective gene associated with cancer.

10 Mar 2011

Study reveals flexibility of neuronal processes underlying conscious perception

Our brains process many more stimuli than we become aware of. Often images enter our brain without being noticed: visual information is being processed, but does not reach consciousness, that is, we do not have an impression of it. Then, what is the difference between conscious and unconscious perception, and can both forms of perception be changed through practice?

10 Mar 2011

CUBN gene mutation linked with albuminuria in individuals with or without diabetes

A team of researchers from the United States and Europe has identified a single genetic mutation in the CUBN gene that is associated with albuminuria both with and without diabetes. Albuminuria is a condition caused by the leaking of the protein albumin into the urine, which is an indication of kidney disease.

9 Mar 2011

Predictability can improve multitasking

Researchers from Rice University and Georgia Institute of Technology have found support for the theory that the brain has three concentric layers of working memory where it stores readily available items. Memory researchers have long debated whether there are two or three layers and what the capacity and function of each layer is.

9 Mar 2011

KineMed extends collaboration with BMY to identify and characterize Alzheimer's biomarkers

KineMed, Inc. announced today the extension of its collaboration with Bristol-Myers Squibb in the area of Alzheimer's disease and other neurodegenerative conditions.

9 Mar 2011

Atherotech announces Sponsorship Agreement with NLA

Aiming to boost advanced lipoprotein testing in lipid education and management, Atherotech Diagnostics Lab announces its Sponsorship Agreement with the National Lipid Association.

9 Mar 2011

Medical Science News

Caspase inhibition can prevent brain inflammation in neurological diseases

St. Joseph's Hospital launches new neuromodulation center in Barrow

First recording of cortically induced neural activity of basal ganglia in Parkinson's disease, dystonia during DBS

New study sheds 'light' on intricate brain cell connections responsible for anxiety

Study: High volume music players can cause neurophysiological changes

Experimental drug effectively shuts off MCL1 gene and induces apoptosis

Swine flu virus may evolve into a deadlier form

Blood biomarker may help decide intake of aspirin or NSAIDs for reduction of cancer risk

Novel sortase-based techniques allow modification of a large variety of different proteins

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

CRT, ICR sign deal with ZoBio to discover and develop cancer drugs

Immunologists identify key cell component that triggers allergic responses to cat dander

Researchers pinpoint a protein responsible for fat storage in the body

Study finds synapses between retinal ganglion cells and starburst amacrine cells distributed asymmetrically

ITCs in vegetables appear to target and block p53 gene linked with cancer

Study reveals flexibility of neuronal processes underlying conscious perception

CUBN gene mutation linked with albuminuria in individuals with or without diabetes

Predictability can improve multitasking

KineMed extends collaboration with BMY to identify and characterize Alzheimer's biomarkers

Atherotech announces Sponsorship Agreement with NLA

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