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A20 protein plays protective role in diseases associated with chronic bowel inflammation: Scientists

Scientists associated with VIB (Flanders Institute for Biotechnology) and Ghent University have discovered that A20 protein plays an important protective role in diseases associated with chronic bowel inflammation. This makes A20 into a promising therapeutic target for the development of new anti-inflammatory drugs.

5 Jul 2010

EMBL scientists develop Fly Digital Embryo to film development of fruit fly, zebrafish's eyes and brain

The scientists at the European Molecular Biology Laboratory in Heidelberg, Germany, who 'fathered' the Digital Embryo have now given it wings, creating the Fly Digital Embryo. In work published today in Nature Methods, they were able to capture fruit fly development on film, and were the first to clearly record how a zebrafish's eyes and midbrain are formed.

5 Jul 2010

Study finds structural similarities in neocortices of humans and chickens

For more than a century, neuroscientists believed that the brains of humans and other mammals differed from the brains of other animals, such as birds (and so were presumably better). This belief was based, in part, upon the readily evident physical structure of the neocortex, the region of the brain responsible for complex cognitive behaviors.

3 Jul 2010

Transplanted beta cells protect themselves by adapting to their new homes

For transplanted beta cells, life is tough. Not only are the insulin-producing cells in a stranger's body, tucked into the liver rather than the pancreas, they are a bit short on oxygen and blood, and they are often exposed to raised levels of glucose.

3 Jul 2010

Karolinska Institutet researchers contribute at ESOF 2010

Researchers and staff from Karolinska Institutet are contributing to Europe's largest cross-disciplinary gathering place with news of everything from neuroscience to bioentrepreneurship. Carl Johan Sundberg, university lecturer and associate professor at Karolinska Institutet, is the founder and initiator of ESOF.

3 Jul 2010

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

Mount Sinai Hospital researchers including Drs. Andras Nagy and Jeff Wrana have discovered new insights into the genesis of stem cells, which will improve the efficiency of stem cell creation for use in tissue regeneration and in the development of new drugs.

3 Jul 2010

Study finds EPB41L3 'protector gene' inactivated in 65% of ovarian cancers

A new gene that normally protects against ovarian cancer is switched-off in two-thirds of cases of the disease, reveals a study published in the journal Neoplasia today.

3 Jul 2010

Rogue stem cells capable of kick-starting melanoma skin cancer development discovered

Researchers at Stanford University School of Medicine in the US have discovered that rogue stem cells appear to be capable of kick-starting the development of melanoma skin cancer in humans.

3 Jul 2010

Heart patients treated for lymphoma at increased risk of cardiac problems

Older patients with Hodgkin lymphoma (HL) and a history of heart disease face a high risk of hospitalization for cardiac complications after completing treatment, according to research published online today in Blood, the journal of the American Society of Hematology. HL is a form of cancer of arising in the lymph nodes, and approximately 8,500 people were diagnosed with the disease in 2009, according to the American Cancer Society.

3 Jul 2010

MabCent finds extraordinary life forms in the Arctic

During its short existence the Centre on Marine Bioactives and Drug Discovery (MabCent) in Tromsø has analysed some 70,000 fractions of Arctic marine organisms. Patents on two molecules have been applied for and applications for another 20 will soon follow.

3 Jul 2010

Further analysis on Bcl11b gene and T-cell behaviouur from Caltech Biologists

When does a cell decide its particular identity? According to biologists at the California Institute of Technology (Caltech), in the case of T cells-immune system cells that help destroy invading pathogens-the answer is when the cells begin expressing a particular gene called Bcl11b.

3 Jul 2010

People with high levels of vitamin B6 and methionine less likiely to develop lung cancer

People with higher blood levels of vitamin B6 and the amino acid methionine appear to have a lower risk of lung cancer, a French study has found. But more research is needed to understand if higher levels of the nutrients directly protect against the disease.

3 Jul 2010

Fluidigm's IFC platform products help perform digital-PCR measurements on single gene

Utilizing Fluidigm Corporation's Dynamic Array™ and Digital Array™ integrated fluidic circuits (IFCs), Stanford University researchers to have discovered a much larger spectrum of differences between individual cells than has previously been demonstrated. Among these differences are the communication capabilities that emerge from the interactions of genetic circuitry that mediates cell-to-cell communication.

2 Jul 2010

Modified Citrus Pectin holds promise against prostate cancer

Researchers at Columbia University recently analyzed the positive effects of Modified Citrus Pectin (MCP) on human and mouse prostate cancer cell lines. The results, as reported by lead researcher Dr. Aaron Katz in the most recent publication of Integrative Cancer Therapies, show that MCP inhibits cell proliferation and induces apoptosis (programmed cell death) in both androgen-dependent and androgen-independent cancer cells in a time and dose-dependent manner.

2 Jul 2010

Twelve type 2 diabetes susceptibility loci identified

An international team co-led by scientists from the University of Michigan have discovered 12 more regions on the genome with DNA variants that are associated with increased risk of type 2 diabetes, bringing the number to 38.

2 Jul 2010

IBM, University of Missouri collaborate to develop cloud computing environment for genomics research

IBM and the University of Missouri today announced a life sciences research initiative using IBM high performance computing technologies to advance the school's bioinformatics research projects. The goal of the initiative is to develop a first-of-a-kind cloud computing environment for genomics research collaboration at a regional level.

2 Jul 2010

Clemizole can yield high-level synergy with protease inhibitor class: Research

Eiger BioPharmaceuticals, Inc., a biotechnology company developing antiviral therapies, announced today the publication of research from the lab of Stanford scientist and Eiger Founder, Dr. Jeffrey Glenn, M.D., Ph.D. and colleagues entitled, "The Hepatitis C Virus (HCV) NS4B RNA Binding Inhibitor Clemizole is Highly Synergistic with HCV Protease Inhibitors".

2 Jul 2010

QR Pharma to present clinical data from mechanism of action study in MCI patients at ICAD 2010

QR Pharma, Inc., a developer of novel drugs to treat Alzheimer's disease (AD), announced today that it has been accepted to present a poster on clinical data from its recent mechanism of action study in mild cognitive impaired (MCI) patients at the International Congress on Alzheimer's Disease (ICAD 2010).

2 Jul 2010

Researchers develop first model of hormone-induced human prostate cancer initiation and progression

Progress toward understanding the role of sex hormones in the growth of prostate cancer—the most common cancer in U.S. men—has been hindered by the lack of a suitable laboratory research model. Now researchers say they have developed the first model of hormone-induced human prostate cancer initiation and progression.

2 Jul 2010

Virus related to hepatitis C discovered in Asian bats

Viral hepatitis affects more than 500 million people worldwide and is a cause of liver failure and liver cancer. While vaccines are available for hepatitis A and B, this is not the case for hepatitis C, which affects as much as two percent of the population in the U.S. Scientists today are reporting discovery of a virus related to hepatitis C in Asian bats, which may provide insights into the origins of the hepatitis C virus and into the mechanisms by which infectious diseases move from other species to humans.

2 Jul 2010

Medical Science News

A20 protein plays protective role in diseases associated with chronic bowel inflammation: Scientists

EMBL scientists develop Fly Digital Embryo to film development of fruit fly, zebrafish's eyes and brain

Study finds structural similarities in neocortices of humans and chickens

Transplanted beta cells protect themselves by adapting to their new homes

Karolinska Institutet researchers contribute at ESOF 2010

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

Study finds EPB41L3 'protector gene' inactivated in 65% of ovarian cancers

Rogue stem cells capable of kick-starting melanoma skin cancer development discovered

Heart patients treated for lymphoma at increased risk of cardiac problems

MabCent finds extraordinary life forms in the Arctic

Further analysis on Bcl11b gene and T-cell behaviouur from Caltech Biologists

People with high levels of vitamin B6 and methionine less likiely to develop lung cancer

Fluidigm's IFC platform products help perform digital-PCR measurements on single gene

Modified Citrus Pectin holds promise against prostate cancer

Twelve type 2 diabetes susceptibility loci identified

IBM, University of Missouri collaborate to develop cloud computing environment for genomics research

Clemizole can yield high-level synergy with protease inhibitor class: Research

QR Pharma to present clinical data from mechanism of action study in MCI patients at ICAD 2010

Researchers develop first model of hormone-induced human prostate cancer initiation and progression

Virus related to hepatitis C discovered in Asian bats

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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