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Scientists develop humanized mouse model to study typhoid fever

Better treatments and prevention for typhoid fever may emerge from a laboratory model that has just been developed for the disease. The model is based on transplanting human immune stem cells from umbilical cord blood into mice that are susceptible to infections.

23 Sep 2010

Metabolon publishes biomarker validation study results for periodontal diseases

Metabolon, Inc., leaders in global metabolomics, biomarker discovery and biochemical analysis, announces the publication of "Assessment of Dentifrice on Periodontal Disease Biomarkers in Gingival Crevicular Fluid", in the Journal of Periodontology.

23 Sep 2010

Northwestern Medicine participates in world's first human embryonic stem cell clinical trial for spinal cord injury

Northwestern Medicine is the first site open for enrollment in a national clinical research trial of a human embryonic stem cell-based therapy for participants with a subacute thoracic spinal cord injury. Following the procedure, participants will receive rehabilitation treatment at The Rehabilitation Institute of Chicago (RIC).

23 Sep 2010

Study may help develop preventative treatments for womb infections

Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have established in mice the mechanism that detects and responds to the presence of bacteria in the womb a discovery that opens up the possibility of new preventative treatments for diseases like pelvic inflammatory disease and Chlamydia.

23 Sep 2010

Scientists create human liver cells using stem cells

Emerging Healthcare Solutions President and CEO Cindy Morrissey said Tuesday that a recent study at the University of Cambridge seems to indicate that realistic stem cell therapies to replace diseased or damaged tissues may be closer than ever.

23 Sep 2010

Beta-Pro donates human pancreatic islet cells to diabetes researcher

The cellular services company Beta-Pro LLC, announced today that it donated more than 300,000 human pancreatic islet cells to nationally renowned diabetes researcher Raghavendra G. Mirmira, M.D., Ph.D., the Eli Lilly & Co. Professor of Pediatric Diabetes, Indiana University School of Medicine, Herman B.

23 Sep 2010

Diagenode releases two monoclonal antibodies to enrich 5-hmC epigenetics research

Diagenode announced today that it has released two additional 5-hmC antibodies to complement its original 5-hmC (rat) monoclonal antibody. The two new 5-hmC monoclonal antibody (mouse) and polyclonal antibody (rabbit) antibodies give researchers additional choices for enriching and analyzing 5-hmC in their methylation studies.

23 Sep 2010

GATC Biotech to purchase PacBio real-time sequencing technology

GATC Biotech announced today that it has agreed to purchase the PacBio RS platform, a single molecule, real-time (SMRT™) sequencing technology. The new PacBio RS will be the fifth sequencing technology for GATC Biotech. The system is planned for installation in early 2011.

22 Sep 2010

Scientists develop new therapy for treatment of skin, lung cancer

Scientists at the University of Granada have developed a new therapy for the treatment of skin and lung cancer. This therapy involves the use of a suicide coliphage-gene (gene E) that can induce death to cells transfected with it.. Their studies have demostrated that this technique is not only effective in vitro (using tumour cell cultures), but also in vivo through the use of experimental animals in which tumours were induced.

22 Sep 2010

Forensic DNA World Map Project launched

United States-based firm Gordon Thomas Honeywell Governmental Affairs (GTH-GA) announced the launch of the Forensic DNA World Map Project (WMP), a new component to GTH-GA's popular DNAResource.com, which monitors developments in forensic DNA policy. GTH-GA's president, Tim Schellberg, made the announcement in Lyon, France during INTERPOL's 6th International DNA User's Conference.

22 Sep 2010

George Higginson Professor to receive 2010 Warren Alpert Foundation Prize

Howard Green, a founding father of regenerative medicine and the George Higginson Professor of Cell Biology at Harvard Medical School, will receive the 2010 Warren Alpert Foundation Prize for developing methodologies leading directly to permanent skin restoration therapy which is saving the lives of thousands of burn patients around the world.

22 Sep 2010

Telomere length associated with higher rate of relapse and lower overall survival in aplastic anemia patients

Among patients receiving immunosuppressive therapy for severe aplastic anemia (a condition in which the bone marrow is unable to produce blood cells), the length of telomeres (chromosome markers of biological aging) was not related to the response to treatment but was associated with a higher rate of relapse (return to low blood cell counts) and lower overall survival, according to a study in the September 22/29 issue of JAMA.

22 Sep 2010

$Spanish researchers confirm genetic risk factor for osteoporosis and bone fractures$

Spanish researchers confirm genetic risk factor for osteoporosis and bone fractures

Spanish researchers have confirmed there is a genetic risk factor for osteoporosis and bone fractures. Although more studies are still needed, these findings will make it possible to take preventive measures.

22 Sep 2010

Protein zyxin necessary for maintenance and repair of cell's cytoskeleton

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have discovered that a protein, zyxin, is necessary for the maintenance and repair of the cell's cytoskeleton, or internal framework, which serves as the muscle and bone of the cell. The research has implications for cancer, as well as other diseases, since alterations in the cytoskeleton are often associated with disease. The research was published in the Sep. 14, 2010, issue of the journal Developmental Cell.

22 Sep 2010

Delphi Genetics licences StabyExpress technology for production of protein vaccines to GSK

Delphi Genetics SA has announced today the signature of a licensing agreement with GlaxoSmithKline for the use of the patented StabyExpress technology for the production of protein vaccines for human use.

22 Sep 2010

Shrink Nanotechnologies leases laboratory space inside TechPortal

Shrink Nanotechnologies, Inc., an innovative nanotechnology company developing products and licensing opportunities in the alternative energy industry, medical diagnostics and sensors, and biotechnology research and development tools businesses, announced today that it has leased laboratory space (the "NanoShrink Lab") inside the TechPortal, an innovative and brand new technology facilitator center for commercial bioscience research companies which are in most cases based on University of California, Irvine research.

22 Sep 2010

Agilent, ISB and ETH Zurich enter second phase of mapping complete human proteome

Ninth Annual World Conference of the Human Proteome Organization -- Agilent Technologies Inc. (NYSE:A) today announced that its collaboration with the Institute for Systems Biology (ISB) and the Swiss Federal Institute of Technology (ETH Zurich) for the mapping of the complete human proteome by mass spectrometry is entering its second phase.

22 Sep 2010

Dr. Shlomo Melmed awarded 9th Endocrine Regulation Prize of the Fondation Ipsen

The international jury under the presidency of Professor Iain Robinson (National Institute for Medical Research, London, UK) awarded today the 9th Endocrine Regulation Prize of the Fondation Ipsen (20.000€) to Dr. Shlomo Melmed (Cedars-Sinai Medical Center, Los Angeles, USA) during the annual congress of the ENEA (European NeuroEndocrine Association) in Liège (Belgium), for his translational approach to endocrinology. Shlomo Melmed is an internationally recognized endocrinologist and an authority on pituitary medicine.

22 Sep 2010

Synthetic lethality boosts effectiveness of molecularly targeted therapies against tumors

Molecularly targeted therapies can reduce tumors rapidly. However, not all tumors respond to the drugs, and even those that do often develop resistance over time. Looking for a way to combat the problem of resistance, researchers at Fox Chase Cancer Center hypothesized that hitting already weakened cancer cells with a second targeted agent could kill them-but only if it was the right second agent.

22 Sep 2010

Study links progressive osteoarthritis to IL-1Ra gene variations

Scientists from University of North Carolina at Chapel Hill School of Medicine and Interleukin Genetics, Inc. announced today findings from a large clinical study to evaluate the role played by genetic factors in the worsening of osteoarthritis.

22 Sep 2010